Photoinduced Ligand-to-Metal Charge Transfer (LMCT) in Organic Synthesis: Reaction Modes and Research Advances DOI
Yingying Yang, Xinxiang Huang, Yi Jin

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

In recent years, visible light-induced ligand-to-metal charge transfer (LMCT) has emerged as an attractive approach for synthesizing a range of functionalized molecules. Compared to conventional photoredox reactions, photoinduced LMCT activation does not depend on redox potential and offers diverse reaction pathways, making it particularly suitable the inert bonds functional modification complex organic This review highlights indispensable role in synthetic chemistry, with focus advancements LMCT-mediated hydrogen atom (HAT), C-C bond cleavage, decarboxylative transformations, radical ligand (RLT) reactions.

Language: Английский

Visible-light induced direct C(sp3)–H functionalization: recent advances and future prospects DOI
Jia‐Lin Tu, Yining Zhu, Pengcheng Li

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(18), P. 5278 - 5305

Published: Jan. 1, 2024

This review summarizes the latest methodological advances in photocatalytic C(sp 3 )–H functionalization, with a particular emphasis on formation of C–P, C–B, C–S bonds, etc ., and some prominent efforts asymmetric C–H functionalization.

Language: Английский

Citations

15
Unleashing the potentiality of metals: synergistic catalysis with light and electricity DOI
Zhengjia Shen, Jia‐Lin Tu, Binbin Huang

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(14), P. 4024 - 4040

Published: Jan. 1, 2024

This review provides a comprehensive overview of metal catalysis in photo-electrochemical systems, discussing reaction mechanisms and offering prospects for this triadic catalytic mode.

Language: Английский

Citations

13
Towards a more Sustainable Photocatalysis using Copper and Iron DOI Creative Commons
Youssef Abderrazak, Oliver Reiser

Current Opinion in Green and Sustainable Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 100998 - 100998

Published: Jan. 1, 2025

Language: Английский

Citations

1
C(sp<sup>3</sup>)‐H Functionalization Using Chlorine Radicals DOI
Masoud Sadeghi

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(13), P. 2898 - 2918

Published: May 18, 2024

Abstract Converting any desired C−H bond to the intended C−Z in a given organic molecule could be final peak of functionalization methodology. Among three types bonds, ubiquitous C( sp 3 )−H has gained particular attention, especially last two decades. There are different ways transform bonds into bonds. The use chlorine radicals is one these methods with promising future. literature review shows that sources have been used for chlorine, including chloride ions (HCl or salts), coordinated chlorides (transition metal complexes), and (organochlorine compounds). However, HCl FeCl most attention among sources. major convert from radicals: 1) oxidation hydrogen salts, 2) photolysis chloride, 3) transition insertion C−Cl This summarizes published research papers on functionalization. Therefore, chlorination reactions which do not play direct role cleavage within scope this review.

Language: Английский

Citations

8
Construction of C–P Bonds from Free Cyclobutanone Oximes and Chlorophosphines via Radical–Radical Coupling DOI
Lulu Yang, Jiale Wu, Yang Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(15), P. 3208 - 3212

Published: April 10, 2024

Herein, we report a catalyst-free reaction of cyclobutanone oximes with chlorophosphines (R2PCl), which forms fragile C═N–O–PR2 species that undergoes N–O homolysis, fragmentation, and radical–radical coupling, leading to the formation cyano-containing phosphine oxides in good yields. The features an situ activation for radical generation, R2PCl plays dual role as both activator reactant.

Language: Английский

Citations

4
Iron Photoredox Catalysis as an Effective Tool for Organic Synthesis via Visible‐Light‐Induced Homolysis (VLIH) DOI
Vishal Srivastava, Praveen P. Singh, Surabhi Sinha

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(4)

Published: Jan. 1, 2025

Abstract Owing to its possible advantages for the environment and economy, photoredox catalysis of organic processes fueled by iron has garnered a lot interest recently. The potential photo‐induced single‐electron transfer (SET) events occurring outside sphere is now well acknowledged. Currently, focus shifted newly discovered photoactivation method that based on an inner‐sphere mode reactivity caused population visible‐light‐induced homolysis (VLIH) states. VLIH activation, in contrast photoredox, specific complexes, offers distinct profiles, does not require redox potentials coincide. These attractive properties have prompted development strategies use this blueprint manufacture highly reactive open‐shell species mild environments. purpose contribution promote novel synthetic techniques sustainable chemical transformations offer educational instrument understanding evolving idea.

Language: Английский

Citations

0
Iron-Catalyzed Multicomponent C–H Alkylation of in Situ Generated Imines via Photoinduced Ligand-to-Metal Charge Transfer DOI
Pengcheng Li, Jia‐Lin Tu,

Ao-Men Hu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(30), P. 6347 - 6352

Published: July 22, 2024

Herein, we describe a novel photoinduced iron-catalyzed strategy for multicomponent C-H alkylation of in situ generated imines. By utilizing the alkyl radicals through iron-mediated photocatalytic activation, imines formed are further subjected to addition reactions, resulting synthesis various secondary and tertiary amine products. This method is simple operate does not require additional oxidants. It applicable inert alkane substrates such as cyclic alkanes, ethers, toluene, ketones. The reaction also compatible with aromatic amines, halogenated well aldehydes, cinnamaldehyde, among other different types aldehydes.

Language: Английский

Citations

1
Recent Progress in Metal-Catalyzed C(sp³)-P Bond Formation DOI
Jia‐Lin Tu, Zhengjia Shen, Binbin Huang

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 168, P. 134352 - 134352

Published: Nov. 1, 2024

Language: Английский

Citations

1
Photoinduced Ligand-to-Metal Charge Transfer (LMCT) in Organic Synthesis: Reaction Modes and Research Advances DOI
Yingying Yang, Xinxiang Huang, Yi Jin

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

In recent years, visible light-induced ligand-to-metal charge transfer (LMCT) has emerged as an attractive approach for synthesizing a range of functionalized molecules. Compared to conventional photoredox reactions, photoinduced LMCT activation does not depend on redox potential and offers diverse reaction pathways, making it particularly suitable the inert bonds functional modification complex organic This review highlights indispensable role in synthetic chemistry, with focus advancements LMCT-mediated hydrogen atom (HAT), C-C bond cleavage, decarboxylative transformations, radical ligand (RLT) reactions.

Language: Английский

Citations

1