Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 132128 - 132128

Published: May 7, 2024

Language: Английский

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Long-Term Effects of SARS-CoV-2 Infection on Metal Homeostasis

Journal of Trace Elements in Medicine and Biology, Journal Year: 2025, Volume and Issue: 88, P. 127625 - 127625

Published: Feb. 27, 2025

Language: Английский

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Integration of metalloproteome and immunoproteome reveals a tight link of iron-related proteins with COVID-19 pathogenesis and immunity

Clinical Immunology, Journal Year: 2024, Volume and Issue: 263, P. 110205 - 110205

Published: April 2, 2024

Language: Английский

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Metal-detection based techniques and their applications in metallobiology

Chemical Science, Journal Year: 2024, Volume and Issue: 15(27), P. 10264 - 10280

Published: Jan. 1, 2024

This perspective summarizes the latest progress in advanced metal-detection based techniques, along with examples of their successful applications as drivers for novel insights elucidating roles metals biology and medicine.

Language: Английский

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Selenium metabolism and selenoproteins function in brain and encephalopathy

Science China Life Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Language: Английский

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Metallomic analysis of urine from individuals with and without Covid-19 infection reveals extensive alterations in metal homeostasis

Journal of Trace Elements in Medicine and Biology, Journal Year: 2024, Volume and Issue: 86, P. 127557 - 127557

Published: Oct. 30, 2024

Language: Английский

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The interaction effect of dietary selenium intake and the IL10 rs1800871 polymorphism on the risk of colorectal cancer: a case–control study in Korea

British Journal Of Nutrition, Journal Year: 2024, Volume and Issue: 131(12), P. 2039 - 2048

Published: March 21, 2024

The importance of Se in human health has received much attention due to its antioxidant properties when it is consumed at an appropriate level. However, the existing evidence limited obtain effective conclusion for colorectal cancer (CRC). Notably, adequate intake was reported Koreans. Furthermore, cytokine secretion and immune function may be affected by dietary Se. Our study aimed explore whether potentially reduces CRC risk

Language: Английский

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Metallomic analysis of urine from individuals with and without Covid-19 infection reveals extensive alterations in metal homeostasis

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: April 19, 2024

Metal ions perform important functions in the body and their concentrations cells tissues are tightly controlled. Alterations metal homeostasis can occur certain disease states including infection. In this study urinary excretion of several metals calcium, cadmium, cobalt, copper, iron, magnesium, nickel, selenium, zinc Covid-19 patients (n=35) control (n=60) individuals, spanning ages sexes. Urinary samples were analysed using ICP-MS differences between Covid-19-infected groups assessed multivariate data analysis univariate employing Student's t-test Pearson's correlation, with significance set at p<0.05. The all significantly higher Covid-infected group (compared to controls), exception which was markedly reduced. increase calcium lower magnesium greater Covid-19-positive individuals aged 41 or over compared those 40 lower. Whilst iron lower, cobalt males females. highlights significant alterations handling a range during It also both age sex-specific homeostasis. results suggest an role for copper infection suggests that other may serve as markers predict progression disease.

Language: Английский

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Lighting Up and Identifying Metal-Binding Proteins in Cells

JACS Au, Journal Year: 2024, Volume and Issue: 4(12), P. 4628 - 4638

Published: Nov. 29, 2024

Metal ions, either essential or therapeutic, play critical roles in life processes the treatment of diseases. Proteins and enzymes are involved metal homeostasis action metallodrugs. Imaging identifying these metal-binding proteins will facilitate elucidation metal-mediated processes. The emerging research field metallomics metalloproteomics has significantly advanced our understanding that metals biology medicine. Fluorescence-based offers possibility not only visualization but also identification living cells tissues. Herein, we summarize different strategies labeling tracking with aid fluorescent probes. We highlight several examples as showcases how this fluorescence-based approach could be utilized metallobiology chemical biology. In conclusion, discuss advantages limitations approaches point out future directions including development more sensitive selective fluorescence probes, integration other omics approaches, well application super-resolution imaging techniques utilize molecules proteins. aim to attract scientists engage exciting field.

Language: Английский

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Selenoproteome depletion enhances oxidative stress and alters neutrophil functions in Citrobacter rodentium infection leading to gastrointestinal inflammation

Free Radical Biology and Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

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