Energy Transfer (EnT)-Mediated Stereoselective Aryl-Heterofunctionalization of Unactivated Alkynes via Radical Rearrangement

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

In this study, we present a novel catalyst-free energy transfer mediated radical rearrangement strategy for the aryl-heterofunctionalization of unactivated alkynes, leading to synthesis polyfunctional olefins with exceptional stereoselectivity. This innovative approach, driven by visible light, exemplifies green chemistry principles eliminating reliance on transition metals, external oxidants, and photocatalysts. The broad applicability our method is demonstrated through successful diverse array compounds, including vinyl sulfones, selenides, sulfides. Preliminary mechanistic insights suggest an mechanism, highlighting efficiency selectivity strategy.

Language: Английский

Photoinduced Carbamoylarylation of Alkynes with N-Aryl Oxamic Acids

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

1,2-Difunctionalization of alkynes is an attractive synthetic protocol, because it can achieve a high step economy and provide various complex organic molecules. This study demonstrates the visible-light-induced carbamoylarylation terminal using N-aryl oxamic acids as bifunctional reagents. The transformation involves addition carbamoyl radicals to alkenes, resulting in 1,4-aryl migration via C(aryl)-N bond cleavage afford corresponding arylacrylamides moderate good yields.

Language: Английский

Efficient and regioselective C=S bond difunctionalization through a three-component radical relay strategy

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110424 - 110424

Published: Sept. 1, 2024

Language: Английский