Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 351, P. 123102 - 123102
Published: Dec. 3, 2024
Language: Английский
Deleted Journal, Journal Year: 2025, Volume and Issue: 7(2)
Published: Feb. 13, 2025
Abstract There is an increase in infectious diseases every year. Heterocyclic compounds have been use as drugs for a long time. Amongst many heterocyclic derivatives, the containing pyrazole core has limelight because of its relative ease synthesis and excellent biological activities. Pyrazoles are aromatic consisting ring structure where two nitrogen atoms adjacent to each other contain three carbon atoms. Over years pyrazoles explored variety pharmacological applications. Herein, this review overviews information related industrially important pyrazoline scaffolds their applications, recent literature on synthesizing providing explanation activity by focusing structural relationship hence affording ideas design scaffolds. Graphical abstract
Language: Английский
Citations
0
The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 27, 2025
We present a novel base-mediated [3+2] cycloaddition for the regioselective synthesis of polysubstituted pyrazoles using 2-alkynyl-1,3-dithianes and sydnones. By exploiting umpolung nucleophilic properties 2-alkynyl-1,3-dithianes, this method achieves efficient pyrazole construction under mild conditions with excellent regioselectivity, broad functional group tolerance, diverse substrate compatibility. Furthermore, unique reactivity dithianyl enables facile derivatization highly functionalized pyrazoles.
Language: Английский
Citations
0
European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 282, P. 117081 - 117081
Published: Nov. 20, 2024
Language: Английский
Citations
2
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 351, P. 123102 - 123102
Published: Dec. 3, 2024
Language: Английский
Citations
0