Optothermal Raman analysis of thermal conductance and boundary resistance in a subwavelength single nanoparticle DOI Creative Commons

Nourhan Barakat,

F. El Haj Hassan, M. Kazan

et al.

Journal of Applied Physics, Journal Year: 2025, Volume and Issue: 137(12)

Published: March 26, 2025

We present optothermal Raman spectroscopy as a powerful technique for characterizing the thermal properties of individual subwavelength nanoparticles. This method enables extraction intrinsic conductance an nanoparticle with average size representative inclusion population and resistance at interface between its surrounding matrix. By overcoming spatial resolution limitations conventional techniques, such scanning microscopy, eliminating need complex nanoscale heat transfer modeling, provides direct, size-independent measurements high accuracy. The involves measuring target nanoparticles embedded in matrix smaller, low-density particles varying mass fractions. These are then fitted to effective medium theory extract both boundary Validation studies were conducted on monoclinic gallium oxide (β-Ga₂O₃, 590 nm) zinc (ZnO, 500 granular silicon matrix, well (Si, 100 carbon β-Ga₂O₃ ZnO particles, bulk-like properties, served benchmarks, while Si exhibited size-dependent behavior. Measurements relied resonance frequency precise thermometric signal, results corroborated by first-principles calculations. providing reliable without intricate offers significant advantages property characterization. versatile holds great promise advancing research materials science nanotechnology.

Language: Английский

A comprehensive review of challenges and advances in exosome-based drug delivery systems DOI Creative Commons

Sushesh Srivatsa Palakurthi,

Brijesh Shah, Sumedha Kapre

et al.

Nanoscale Advances, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Key challenges in exosomal based therapies.

Language: Английский

Citations

18

Revolution in Cancer Treatment Methods: Perspective Review of Factors Affecting the Final Results of Nanoparticles Used in Magnetic Fluid Hyperthermia DOI Creative Commons

parisa oskoui,

Maryam Rezvani

Health Sciences Review, Journal Year: 2025, Volume and Issue: unknown, P. 100212 - 100212

Published: Jan. 1, 2025

Language: Английский

Citations

2

Nanozyme-Based Cancer Nanotheranostics: Emerging Applications and Challenges in Brain Cancer Therapeutics DOI Creative Commons
Alexandra A.P. Mansur, Herman S. Mansur

Journal of Nanotheranostics, Journal Year: 2025, Volume and Issue: 6(1), P. 4 - 4

Published: Jan. 31, 2025

Regrettably, despite undeniable advances in cancer diagnosis and therapy, primary brain (or cancer) remains one of the deadliest forms malignant tumors, where glioblastoma (GBM) is known as most diffuse glioma astrocytic lineage. Fortunately, to improve this scenario, remarkable progress nanotechnology has brought new promise raised expectations treatment. Nanomedicine, principally an area amalgamating with biology medicine, demonstrated a pivotal role, starting earliest detection while also offering novel multimodal therapy alternatives. In vast realm nanotechnology, nanozymes, type nanomaterial intrinsic enzyme-like activities characteristics connecting fields nanocatalysts, enzymology, biology, have emerged powerful nanotools for theranostics. Hence, fascinating field research experienced exponential growth recent years. As it virtually impossible cover all literature on broad domain science paper, review focuses presenting multidisciplinary approach, its content extending from fundamental knowledge nanozymes enzyme-mimicking catalysis targeting cancers. Although we are at very early stages research, can be envisioned that strategic development theranostics will positively offer disruptive nanoplatforms future nano-oncology.

Language: Английский

Citations

2

A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks DOI
Ali Khorasani, Seyed Morteza Naghib

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141394 - 141394

Published: Feb. 1, 2025

Language: Английский

Citations

2

Nanogels in Biomedical Engineering: Revolutionizing Drug Delivery, Tissue Engineering, and Bioimaging DOI

Atieh Janmaleki Dehchani,

Aliakbar Jafari,

Farangis Shahi

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(10)

Published: Oct. 1, 2024

ABSTRACT Nanogels represent a significant innovation in the fields of nanotechnology and biomedical engineering, combining properties hydrogels nanoparticles to create versatile platforms for drug delivery, tissue bioimaging, other applications. These nanoscale hydrogels, typically ranging from 10 1000 nm, possess unique characteristics such as high water content, biocompatibility, ability encapsulate both hydrophilic hydrophobic molecules. The review explores synthesis, structural configurations, stimuli‐responsive nature nanogels, highlighting their adaptability targeted including across challenging barriers like blood–brain barrier. Furthermore, paper delves into applications particularly delivery systems, demonstrating potential revolutionize these fields. Despite promising preclinical results, challenges remain translating technologies clinical practice, issues related stability, scalability, regulatory approval. concludes by discussing future perspectives, emphasizing need further research optimize ultimately aiming enhance efficacy safety settings.

Language: Английский

Citations

11

Thermoresponsive Nanocarriers Transduced by Inorganic Nanoparticles: Design Considerations and Applications in Drug Delivery DOI Creative Commons
Anamarija Nikoletić, Mirela Maleković, Gül Kozalak

et al.

Helvetica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Abstract Thermoresponsive polymers, which undergo phase transitions within physiologically tolerated temperatures, are key to developing drug delivery systems (DDS) with precise spatial and temporal control, potentially addressing challenges associated the treatment of complex diseases. Inorganic nanoparticles unique optical, electronic, magnetic properties serve as efficient transducers, converting external stimuli into localized heat trigger thermoresponsive nanocarriers. This review explores design application nanocarriers transduced by inorganic DDS. Following a brief description temperature‐triggered transition polymers generation mechanisms nanoparticles, strategies integrate these components hybrid described. Examples demonstrating utility advanced DDS discussed, highlighting their potential for release alongside theranostic capabilities combining therapy imaging. Despite in design, synthesis, biological applications, polymer‐inorganic hybrids hold immense promise transforming biomedical innovations.

Language: Английский

Citations

0

Magnetically Triggered Drug-Release System and Magnetic Caged Calcium Using Iron Oxide Nanoparticles and Hydrogels DOI
Satoshi Okada,

Yuka Takashima,

Hiroyuki Nakamura

et al.

ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Language: Английский

Citations

0

A Compendium of Magnetic Nanoparticle Essentials: A Comprehensive Guide for Beginners and Experts DOI Creative Commons
Carlos O. Amorim

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(1), P. 137 - 137

Published: Jan. 20, 2025

Magnetic nanoparticles (MNPs) are advanced materials that combine the unique properties of magnetic and nanoscale dimensions, enabling a wide range applications in biomedicine, environmental science, information technology. This review provides comprehensive yet accessible introduction to fundamental principles, characterization techniques, diverse MNPs, with focus on their properties, such as superparamagnetism, single-domain behavior, surface effects. It also delves into classification critical role parameters like anisotropy blocking temperature. Emphasis is placed routine methods, including X-ray diffraction, electron microscopy, magnetometry, well concepts hyperthermia self-regulated heating. Designed for newcomers experts alike, this serves both an educational guide quick-reference resource, ensuring clarity while maintaining scientific rigor.

Language: Английский

Citations

0

Application and advances of multifunctional magnetic nanoparticles in cross-disciplinary research: From design to detection, imaging, and therapy DOI
Yujie Zhao, Liyi Zhou, Jiali Ren

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216590 - 216590

Published: March 4, 2025

Language: Английский

Citations

0

Functional mixed metal oxide nanomaterials: a comprehensive review of their hyperthermic potential in cancer therapy DOI
Amol B. Pandhare, Swapnajit V. Mulik, Santosh S. Patil

et al.

New Journal of Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review provides a comprehensive and well-structured analysis of magnetic hyperthermia therapy (MHT) as potential cancer treatment.

Language: Английский

Citations

0