Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
10
Published: Jan. 16, 2024
There
is
a
huge
gap
between
food
production
and
the
exploding
population
demands
in
various
parts
of
world,
especially
developing
countries.
This
increases
chances
malnutrition,
leading
to
increased
disease
incidence
need
for
functional
foods
reduce
mortality.
Pleurotus
ostreatus
are
edible
mushrooms
that
cheaply
sourced
rich
nutrient
with
potential
be
harnessed
toward
addressing
present
future
crisis
while
serving
as
prevention
treatment.
study
evaluated
nutritional,
proximate,
vitamins
amino
acids
contents
.
The
proximate
composition
this
revealed
it
contains
43.42%
carbohydrate,
23.63%
crude
fiber,
17.06%
protein,
8.22%
ash,
1.21%
lipid
moisture
content
91.01
6.46%
fresh
dry
samples
ostreatus,
respectively
monosaccharide
disaccharide
profile
presence
glucose
(55.08
g/100
g),
xylose
(7.19
fructose
(19.70
galactose
(17.47
trehalose
(7.37
chitobiose
(11.79
maltose
(29.21
sucrose
(51.60
g)
lower
amounts
cellobiose
(0.01
erythrose
(0.48
other
unidentified
sugars.
Potassium,
Iron
Magnesium
were
highest
minerals
12.25
mg,
9.66
mg
7.00
amounts,
respectively.
vitamin
A
(2.93
IU/100
C
(16.46
mg/100
E
(21.50
B
B2
having
concentration
92.97
mg/kg.
acid
scores
showed
had
more
non-essential
(564.17
than
essential
(67.83
ratio
0.11.
Lysine
(23.18
was
aspartic
(492.12
mg/kg)
It
higher
acidic
acids,
492.12
g
(77.87%),
followed
by
neutral
106.66
(16.88%)
least
basic
23.18
(3.67%).
Based
on
nutritional
assessment
analyzed
study,
can
concluded
serve
an
important
source
exploited
meet
increasing
micronutrient
deficiencies
many
Frontiers in Immunology,
Journal Year:
2020,
Volume and Issue:
11
Published: Nov. 30, 2020
The
intestinal
microbiota,
composed
of
a
large
population
microorganisms,
is
often
considered
"forgotten
organ"
in
human
health
and
diseases.
Increasing
evidence
indicates
that
dysbiosis
the
microbiota
closely
related
to
colorectal
cancer
(CRC).
roles
for
microorganisms
initiated
facilitated
CRC
process
are
becoming
increasingly
clear.
Hypothesis
models
have
been
proposed
illustrate
complex
relationship
between
CRC.
Recent
studies
identified
Streptococcus
bovis,
enterotoxigenic
Bacteroides
fragilis,
Fusobacterium
nucleatum,
Enterococcus
faecalis,
Escherichia
coli,
Peptostreptococcus
anaerobius
as
candidate
pathogens.
In
this
review,
we
summarized
mechanisms
involved
microbiota-related
carcinogenesis,
including
inflammation,
pathogenic
bacteria,
their
virulence
factors,
genotoxins,
oxidative
stress,
bacterial
metabolites,
biofilm.
We
also
described
clinical
values
novel
strategies
preventing
treating
Advanced Drug Delivery Reviews,
Journal Year:
2020,
Volume and Issue:
163-164, P. 65 - 83
Published: Jan. 1, 2020
Significant
research
and
preclinical
investment
in
cancer
nanomedicine
has
produced
several
products,
which
have
improved
care.
Nevertheless,
there
exists
a
perception
that
'has
not
lived
up
to
its
promise'
because
the
number
of
approved
products
their
clinical
performance
are
modest.
Many
these
analyses
do
consider
long
history
many
developed
from
iron
oxide
nanoparticles.
Iron
nanoparticles
enjoyed
use
for
about
nine
decades
demonstrating
safety,
considerable
utility
versatility.
FDA-approved
applications
include
diagnosis,
hyperthermia
therapy,
deficiency
anemia.
For
nanomedicine,
this
wealth
experience
is
invaluable
provide
key
lessons
highlight
pitfalls
pursuit
nanotechnology-based
therapeutics.
We
review
with
systemic
liposomal
drug
delivery
parenteral
therapy
anemia
(IDA)
note
success
injectable
exploits
inherent
interaction
between
(innate)
immune
system,
designers
seek
avoid.
Magnetic
fluid
hyperthermia,
harnesses
magnetic
hysteresis
heating
treating
humans
only
Despite
successful
demonstration
enhance
overall
survival
trials,
thermal
medicine
struggles
establish
presence.
physical
biological
attributes
approach,
suggest
reasons
barriers
acceptance.
Finally,
despite
extensive
new
exciting
points
surprising
immune-modulating
potential.
Recent
data
demonstrate
interactions
cells
can
induce
anti-tumor
responses.
These
present
opportunities
explore
additional
venerable
technology.
Clinical
poignant
case
studies
opportunities,
complexities,
challenges
nanomedicine.
They
also
illustrate
need
revised
paradigms
multidisciplinary
approaches
develop
translate
nanomedicines
into
BMC Medicine,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Feb. 21, 2023
Abstract
Background
Evidence
from
observational
studies
and
clinical
trials
suggests
that
the
gut
microbiota
is
associated
with
cancer.
However,
causal
association
between
cancer
remains
to
be
determined.
Methods
We
first
identified
two
sets
of
based
on
phylum,
class,
order,
family,
genus
level
information,
data
were
obtained
IEU
Open
GWAS
project.
then
performed
two-sample
Mendelian
randomisation
(MR)
determine
whether
causally
eight
types.
Furthermore,
we
a
bi-directional
MR
analysis
examine
direction
relations.
Results
11
relationships
genetic
liability
in
microbiome
cancer,
including
those
involving
Bifidobacterium
.
found
17
strong
associations
Moreover,
24
using
multiple
datasets.
Conclusions
Our
revealed
was
cancers
may
useful
providing
new
insights
for
further
mechanistic
microbiota-mediated
Advanced Materials,
Journal Year:
2021,
Volume and Issue:
33(38)
Published: Aug. 4, 2021
Abstract
Bacteria
are
one
of
the
main
groups
organisms,
which
dynamically
and
closely
participate
in
human
health
disease
development.
With
integration
chemical
biotechnology,
bacteria
have
been
utilized
as
an
emerging
delivery
system
for
various
biomedical
applications.
Given
unique
features
such
their
intrinsic
biocompatibility
motility,
bacteria‐based
systems
drawn
wide
interest
diagnosis
treatment
diseases,
including
cancer,
infectious
kidney
failure,
hyperammonemia.
Notably,
at
interface
biotechnology
bacteria,
many
research
opportunities
initiated,
opening
a
promising
frontier
application.
Herein,
current
synergy
design
principles
systems,
microbial
modulation,
clinical
translation
reviewed,
with
special
focus
on
advances
therapy.
