Metabolism and Target Organ Damage,
Journal Year:
2023,
Volume and Issue:
3(1), P. 4 - 4
Published: Jan. 1, 2023
The
persistence
of
Covid-19
infection
for
more
than
four
weeks
after
the
acute
phase
is
defined
as
long
syndrome.
This
condition,
otherwise
by
signs
and
symptoms
12
weeks,
shares
several
features
with
diabetes
mellitus:
mellitus
infections
have
a
pandemic
dimension,
are
characterized
an
inflammatory
milieu,
show
bidirectional
relationship.
Diabetic
patients
appear
likely
to
develop
syndrome
non-diabetic
individuals.
chronicity
favors
development
new
cases
diabetes.
In
this
short
review,
we
discuss
evidence
supporting
link
between
mellitus,
focusing
on
epidemiological
pathophysiological
aspects
dangerous
Deleted Journal,
Journal Year:
2022,
Volume and Issue:
1(1), P. 21 - 28
Published: Dec. 5, 2022
Currently,
studies
have
shown
that
one
in
three
people
infected
with
coronavirus
disease-19
(COVID-19)
is
likely
to
had
long-term
exposure
COVID-19,
known
as
COVID-19.
Clinical
indicate
many
the
severe
acute
respiratory
syndrome
Coronavirus-2
(SARS-CoV-2)
COVID-19
pandemic
exposure.
According
study,
it
has
been
said
diabetes
and
obesity,
who
received
organ
transplants,
are
more
suffer
from
this
effect
of
In
article,
effects
on
neurological
disability
patients
analyzed
help
a
neuromachine
learning
model.
The
proposed
model
also
shows
COVID
problem
does
not
depend
factors
such
race,
age,
gender,
socioeconomic
status
those
people.
model,
suffering
problems
continue
physical
fatigue
shortness
breath
regularly
monitored
classified
per
instructions.
Even
after
they
recover
disease,
various
side
seen.
Deleted Journal,
Journal Year:
2023,
Volume and Issue:
1(1), P. 22 - 29
Published: Jan. 1, 2023
Currently,
studies
have
shown
that
one
in
three
people
infected
with
coronavirus
disease-19
(COVID-19)
is
likely
to
had
long-term
exposure
COVID-19,
known
as
COVID-19.
Clinical
indicate
many
the
severe
acute
respiratory
syndrome
Coronavirus-2
(SARS-CoV-2)
COVID-19
pandemic
exposure.
According
study,
it
has
been
said
diabetes
and
obesity,
who
received
organ
transplants,
are
more
suffer
from
this
effect
of
In
article,
effects
on
neurological
disability
patients
analyzed
help
a
neuromachine
learning
model.
The
proposed
model
also
shows
COVID
problem
does
not
depend
factors
such
race,
age,
gender,
socioeconomic
status
those
people.
model,
suffering
problems
continue
physical
fatigue
shortness
breath
regularly
monitored
classified
per
instructions.
Even
after
they
recover
disease,
various
side
seen.
International Journal of Environmental Research and Public Health,
Journal Year:
2024,
Volume and Issue:
21(3), P. 325 - 325
Published: March 11, 2024
The
COVID-19
pandemic
has
resulted
in
a
growing
number
of
patients
experiencing
persistent
symptoms
and
physiological
changes
after
recovering
from
acute
SARS-CoV-2
infection,
known
as
Long
COVID.
COVID
is
characterized
by
recurring
inflammation
across
multiple
organ
systems.
Diagnosis
can
be
challenging,
influenced
factors
like
demographics,
comorbidities,
immune
responses.
impacts
various
systems
have
neuropsychological
effects.
Health
disparities,
particularly
related
to
race,
contribute
higher
burden
infection
ongoing
minority
populations.
Managing
entails
addressing
spectrum
that
encompass
physical,
cognitive,
psychological
aspects.
recovery
period
for
with
vary
significantly,
the
severity
disease,
hospitalization,
age.
Currently,
there
are
no
universally
effective
treatments,
although
certain
interventions
show
promise,
necessitating
further
research.
Self-management
rehabilitation
programs
provide
relief,
but
more
research
needed
establish
their
effectiveness.
Preventive
measures
such
vaccination
use
antiviral
medications
metformin.
It
imperative
conduct
develop
evidence-based
guidelines
gain
better
understanding
long-term
implications
COVID-19.
could
substantial
economic
impact
on
labor
market,
productivity,
healthcare
expenditures,
overall
growth.
To
address
challenges
complications
face,
focus
strategies
promoting
telework
flexible
work
arrangements
accommodate
diverse
symptoms,
chronic
fatigue
other
In
conclusion,
this
review
emphasizes
multifaceted
complexity
need
its
potential
health
impacts.
EClinicalMedicine,
Journal Year:
2023,
Volume and Issue:
66, P. 102345 - 102345
Published: Dec. 1, 2023
BackgroundThe
association
of
COVID-19
with
the
development
new-onset
diabetes
has
been
recently
investigated
by
several
groups,
yielding
controversial
results.
Population
studies
currently
available
in
literature
are
mostly
focused
on
type
1
(T1D),
comparing
patients
a
SARS-CoV-2
positive
test
to
individuals
without
COVID-19,
especially
paediatric
populations.
In
this
study,
we
sought
determine
incidence
2
(T2D)
before
and
during
pandemic.MethodsIn
longitudinal
cohort
analysed
followed
up
over
6-year
period
using
an
Interrupted
Time
Series
approach,
i.e.
3-years
pandemic.
We
data
obtained
from
>200,000
adults
Naples
(Italy)
January
1st
2017
December
31st
2022.
manner,
had
opportunity
compare
newly
diagnosed
T2D
(2017–2019)
(2020–2022)
The
key
inclusion
criteria
were
age
>18-year-old
availability
for
observation;
diagnosis
excluded.
main
outcome
study
was
new
T2D,
as
defined
International
Classification
Diseases
10
(ICD-X),
including
prescription
antidiabetic
therapies
more
than
30
days.FindingsA
total
234,956
subjects
followed-up
at
least
or
pandemic
included
study;
among
these,
216,498
pre-pandemic
years
216,422
years.
rate
4.85
(95%
CI,
4.68–5.02)
per
1000
person-years
2017–2019,
vs
12.21
11.94–12.48)
2020–2022,
increase
about
twice
half.
Moreover,
doubling
time
number
diagnoses
estimated
unadjusted
Poisson
model
97.12
40.51–153.75)
months
prepandemic
23.13
16.02–41.59)
Interestingly,
these
findings
also
confirmed
when
examining
prediabetes.InterpretationOur
200,000
adult
participants
indicate
that
significantly
higher
compared
pre-COVID-19
phase.
As
consequence,
epidemiology
disease
may
change
terms
rates
outcomes
well
public
health
costs.
survivors,
prediabetes,
require
specific
clinical
programs
prevent
T2D.FundingThe
US
National
Institutes
Health
(NIH:
NIDDK,
NHLBI,
NCATS),
Diabetes
Action
Research
Education
Foundation,
Weill-Caulier
Hirschl
Trusts.
Frontiers in Immunology,
Journal Year:
2023,
Volume and Issue:
14
Published: Dec. 22, 2023
Significance
This
review
discusses
the
coronavirus
disease
2019
(COVID-19)
pathophysiology
in
context
of
diabetes
and
intracellular
reactions
by
COVID-19,
including
mitochondrial
oxidative
stress
storms,
ROS
long
COVID.
Recent
advances
The
COVID
is
suffered
~10%
COVID-19
patients.
Even
virus
does
not
exist,
patients
suffer
for
even
over
a
year,
could
be
mitochondria
dysregulation
disease.
Critical
issues
Patients
who
recover
from
can
develop
new
or
persistent
symptoms
multi-organ
complications
lasting
weeks
months,
called
underlying
mechanisms
involved
still
unclear.
Once
persist,
they
cause
significant
damage,
leading
to
numerous,
symptoms.
Future
directions
A
comprehensive
map
stages
pathogenetic
related
effective
drugs
treat
prevent
it
are
required,
which
will
aid
development
future
treatments
symptom
relief.
Journal of Pharmacology and Experimental Therapeutics,
Journal Year:
2024,
Volume and Issue:
389(1), P. 34 - 39
Published: Feb. 9, 2024
Emerging
evidence
indicates
that
the
relationship
between
coronavirus
disease
2019
(COVID-19)
and
diabetes
is
2-fold:
1)
it
known
presence
of
other
metabolic
alterations
poses
a
considerably
high
risk
to
develop
severe
COVID-19;
2)
patients
who
survived
acute
respiratory
syndrome
2
(SARS-CoV-2)
infection
have
an
increased
developing
new-onset
diabetes.
However,
mechanisms
underlying
this
association
are
mostly
unknown,
there
no
reliable
biomarkers
predict
development
In
present
study,
we
demonstrate
specific
microRNA
(miR-34a)
contained
in
circulating
extracellular
vesicles
released
by
endothelial
cells
reliably
predicts
COVID-19.
This
was
independent
age,
sex,
body
mass
index
(BMI),
hypertension,
dyslipidemia,
smoking
status,
D-dimer.
SIGNIFICANCE
STATEMENT:
We
for
first
time
able
after
having
contracted
(COVID-19).
Our
findings
also
relevant
when
considering
emerging
importance
post-acute
sequelae
COVID-19,
with
systemic
manifestations
observed
even
months
viral
negativization
(long
COVID).
Diseases,
Journal Year:
2024,
Volume and Issue:
12(5), P. 95 - 95
Published: May 6, 2024
Long
COVID
affects
both
children
and
adults,
including
subjects
who
experienced
severe,
mild,
or
even
asymptomatic
SARS-CoV-2
infection.
We
have
provided
a
comprehensive
overview
of
the
incidence,
clinical
characteristics,
risk
factors,
outcomes
persistent
COVID-19
symptoms
in
encompassing
vulnerable
populations,
such
as
pregnant
women
oncological
patients.
Our
objective
is
to
emphasize
critical
significance
adopting
an
integrated
approach
for
early
detection
appropriate
management
long
COVID.
The
incidence
severity
can
significant
impact
on
quality
life
patients
course
disease
case
pre-existing
pathologies.
Particularly,
fragile
patients,
presence
PASC
related
significantly
worse
survival,
independent
from
vulnerabilities
treatment.
It
important
try
achieve
recognition
management.
Various
mechanisms
are
implicated,
resulting
wide
range
presentations.
Understanding
specific
factors
involved
crucial
tailoring
effective
interventions
support
strategies.
Management
approaches
involve
biopsychosocial
assessments
treatment
comorbidities,
autonomic
dysfunction,
well
multidisciplinary
rehabilitation.
overall
one
gradual
improvement,
with
recovery
observed
majority,
though
not
all,
As
research
long-COVID
continues
evolve,
ongoing
studies
likely
shed
more
light
intricate
relationship
between
chronic
diseases,
status,
cardiovascular
psychiatric
disorders,
effects
This
information
could
guide
healthcare
providers,
researchers,
policymakers
developing
targeted
interventions.
