Examining the relationship between public stigma, models of addiction, and addictive disorders DOI
Samantha Rundle, Abby L. Goldstein, Jeffrey D. Wardell

et al.

Addiction Research & Theory, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 7

Published: June 21, 2024

Background The stigmatization of addiction has been identified as a barrier to treatment-seeking among individuals with substance use concerns. Although some evidence exists that beliefs in different models (MOAs) are associated stigma, the research is limited several ways. aim current study understand relationship between MOAs and public stigma toward disorders behavioral addictions.

Language: Английский

Improving translation of animal models of addiction and relapse by reverse translation DOI
Marco Vènniro, Matthew L. Banks, Markus Heilig

et al.

Nature reviews. Neuroscience, Journal Year: 2020, Volume and Issue: 21(11), P. 625 - 643

Published: Oct. 6, 2020

Language: Английский

Citations

181
Candidate biomarkers in psychiatric disorders: state of the field DOI Open Access
Anissa Abi‐Dargham, Scott J. Moeller, Farzana Ali

et al.

World Psychiatry, Journal Year: 2023, Volume and Issue: 22(2), P. 236 - 262

Published: May 9, 2023

The field of psychiatry is hampered by a lack robust, reliable and valid biomarkers that can aid in objectively diagnosing patients providing individualized treatment recommendations. Here we review critically evaluate the evidence for most promising psychiatric neuroscience literature autism spectrum disorder, schizophrenia, anxiety disorders post‐traumatic stress major depression bipolar substance use disorders. Candidate reviewed include various neuroimaging, genetic, molecular peripheral assays, purposes determining susceptibility or presence illness, predicting response safety. This highlights critical gap biomarker validation process. An enormous societal investment over past 50 years has identified numerous candidate biomarkers. However, to date, overwhelming majority these measures have not been proven sufficiently reliable, useful be adopted clinically. It time consider whether strategic investments might break this impasse, focusing on limited number candidates advance through process definitive testing specific indication. Some N170 signal, an event‐related brain potential measured using electroencephalography, subgroup identification within disorder; striatal resting‐state functional magnetic resonance imaging (fMRI) measures, such as connectivity index (SCI) abnormalities (FSA) index, prediction schizophrenia; error‐related negativity (ERN), electrophysiological first onset generalized structural connectomic social disorder. Alternate forms classification may conceptualizing Collaborative efforts allowing inclusion biosystems beyond genetics neuroimaging are needed, online remote acquisition selected naturalistic setting mobile health tools significantly field. Setting benchmarks well‐defined target application, along with development appropriate funding partnership mechanisms, would also crucial. Finally, it should never forgotten that, actionable, will need clinically predictive at individual level viable clinical settings.

Language: Английский

Citations

161
Choosing appropriate language to reduce the stigma around mental illness and substance use disorders DOI Open Access
Nora D. Volkow, Joshua A. Gordon, George F. Koob

et al.

Neuropsychopharmacology, Journal Year: 2021, Volume and Issue: 46(13), P. 2230 - 2232

Published: July 19, 2021

Language: Английский

Citations

115
The stigma of alcohol-related liver disease and its impact on healthcare DOI
Georg Schomerus, Anya Leonhard, Jakob Manthey

et al.

Journal of Hepatology, Journal Year: 2022, Volume and Issue: 77(2), P. 516 - 524

Published: May 5, 2022

Language: Английский

Citations

105
Hazardous drinking and alcohol use disorders DOI

James MacKillop,

Roberta Agabio, Sarah W. Feldstein Ewing

et al.

Nature Reviews Disease Primers, Journal Year: 2022, Volume and Issue: 8(1)

Published: Dec. 22, 2022

Language: Английский

Citations

98
HIV-Related Stigma Research as a Priority at the National Institutes of Health DOI
Gregory L. Greenwood, Amber Wilson, Geetha P. Bansal

et al.

AIDS and Behavior, Journal Year: 2021, Volume and Issue: 26(S1), P. 5 - 26

Published: April 22, 2021

Language: Английский

Citations

64
Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Care Professionals DOI Creative Commons
Alene Kennedy‐Hendricks,

Emma E. McGinty,

Amber Summers

et al.

JAMA Network Open, Journal Year: 2022, Volume and Issue: 5(2), P. e2146971 - e2146971

Published: Feb. 4, 2022

Importance

Stigma toward people with opioid use disorder (OUD) is pervasive in clinical settings, impeding delivery of high-quality care. To date, no study has evaluated the effect different stigma-reduction messages or messengers among health care professionals.

Objective

evaluate OUD-related delivered by on stigma and attitudes OUD

Design, Setting, Participants

This randomized trial examined effects a visual campaign alone combination written narrative vignette from perspective 1 3 messengers. Health professionals US were recruited 2 national online survey panels (Ipsos KnowledgePanel SurveyHealthcareGlobus). A total 1842 participants completed web-based measuring November 13 to 30, 2020.

Interventions

Eight groups exposed message frames. One frame (Words Matter) emphasized harm stigmatizing language, other (Medication Treatment Works) focused effectiveness medications approved Food Drug Administration for treatment OUD. Message frames communicated through either simulated patient OUD, clinician, system administrator.

Main Outcomes Measures

Dimensions measured 5-point Likert scales that included items about desire social distance perception individual blame as medical condition, support increased governmental spending treatment. The level warmth felt was feeling thermometer (range, 0-100 points).

Results

Among participants, mean (SD) age 47 (13) years; 1324 (71.9%) female, 145 (7.9%) Hispanic, 140 (7.6%) non-Hispanic Black, 1344 (73.0%) White, 213 (11.6%) race (ie, individuals who did not self-report Black White ethnicity Hispanic). Compared nonexposure, exposure communicating importance nonstigmatizing language associated lower probability (difference, −16.8 percentage points, 95% CI, −26.1 −7.4;P < .001) unwillingness have person marry into family (a measure preference) 7.2-point (95% 3.2-11.1;P higher rating. Participants combined value medication also had significantly levels compared those nonexposed control group (eg, neighbor: difference, −15.3 points; −24.6 −6.0;P = .001).

Conclusions Relevance

In this study, effective reduced Stigma-reduction efforts targeting may improve capacity serve

Trial Registration

ClinicalTrials.gov Identifier:NCT05127707

Language: Английский

Citations

40
Stigmatization of people with addiction by health professionals: Current knowledge. A scoping review DOI Creative Commons

Anthony Cazalis,

Laura Lambert, Marc Auriacombe

et al.

Drug and Alcohol Dependence Reports, Journal Year: 2023, Volume and Issue: 9, P. 100196 - 100196

Published: Oct. 24, 2023

Stigma of people with substance and non-substance use disorders (SNSUD) is a long-known phenomenon. The aim this review was to assess the stigmatization, by health professionals, SNSUD, its characteristics change over time. A scoping literature reviews conducted systematic search PubMed, Scopus PsycINFO databases. From 19 selected reviews, all focused on SUD (PWSUD) only 20% 51% professionals had negative attitudes/beliefs about SUD. Addiction training clinical experience PWSUD were associated less attitude. Health professionals' beliefs, lack time or support involvement in addiction care. Tobacco disorder, SUDs other than alcohol tobacco, relapse, psychiatric comorbidity criminal records more influence several variables potentially related stigmatization inconsistent across reviews. evolution not systematically assessed showed mixed results. has an impact their care, some could reduce importance: moral model addiction, training, time, role support. Teaching what according medical chronic disease model, developing stigma-focused improve caregivers' attitudes further stigma. Further studies are needed determine whether stigma changed characterize for disorders.

Language: Английский

Citations

26
Management of alcohol use disorder in patients with chronic liver disease DOI Creative Commons
Jessica L. Mellinger, Anne C. Fernandez, Gerald Scott Winder

et al.

Hepatology Communications, Journal Year: 2023, Volume and Issue: 7(7)

Published: June 14, 2023

Alcohol use disorder (AUD) rates have risen dramatically in the United States, resulting increasing of alcohol-associated liver disease (ALD), but many patients struggle to access alcohol treatment. AUD treatment improves outcomes, including mortality, and represents most urgent means by which care can be improved for those with (including ALD others) AUD. involves 3 steps: detecting use, diagnosing AUD, directing Detecting involve questioning during clinical interview, standardized surveys, biomarkers. Identifying are interview-based processes that should ideally performed a trained addiction professional, nonaddiction clinicians surveys determine severity hazardous drinking. Referral formal made, especially where more severe is suspected or identified. Therapeutic modalities numerous include different forms one-on-one psychotherapy, such as motivational enhancement therapy cognitive behavior therapy, group community mutual aid societies (such Alcoholics Anonymous), inpatient treatment, relapse prevention medications. Finally, integrated approaches build strong relationships between professionals hepatologists medical providers caring crucial improving this population.

Language: Английский

Citations

23
“The post-COVID era”: challenges in the treatment of substance use disorder (SUD) after the pandemic DOI Creative Commons
Hugo López‐Pelayo, Henri‐Jean Aubin, Colin Drummond

et al.

BMC Medicine, Journal Year: 2020, Volume and Issue: 18(1)

Published: July 31, 2020

Abstract Background Citizens affected by substance use disorders are high-risk populations for both SARS-CoV-2 infection and COVID-19-related mortality. Relevant vulnerabilities to COVID-19 in people who suffer described previous communications. The pandemic offers a unique opportunity reshape update addiction treatment networks. Main body Renewed systems should be based on these seven pillars: (1) telemedicine digital solutions, (2) hospitalization at home, (3) consultation-liaison psychiatric services, (4) harm-reduction facilities, (5) person-centered care, (6) promote paid work improve quality of life with disorders, (7) integrated care. three “best buys” the World Health Organization (reduce availability, increase prices, ban advertising) still valid. Additionally, new strategies must implemented systematically deal (a) fake news concerning legal illegal drugs (b) controversial scientific information. Conclusion heroin four decades ago was last time that were updated many western countries. A revised modernized network include improved access facilitated where appropriate technology; more care specialists supporting non-specialists; reducing stigma experienced SUDs.

Language: Английский

Citations

62