Population bottlenecks constrain host microbiome diversity and genetic variation impeding fitness DOI Creative Commons
Michael Ørsted, Erika Yashiro, Ary A. Hoffmann

et al.

PLoS Genetics, Journal Year: 2022, Volume and Issue: 18(5), P. e1010206 - e1010206

Published: May 23, 2022

It is becoming increasingly clear that microbial symbionts influence key aspects of their host’s fitness, and vice versa . This may fundamentally change our thinking about how microbes hosts interact in influencing fitness adaptation to changing environments. Here we explore reductions population size commonly experienced by threatened species microbiome diversity. Consequences such are normally interpreted terms a loss genetic variation, increased inbreeding associated depression. However, effects bottlenecks might also be mediated through diversity, as functionally important microbes. utilise 50 Drosophila melanogaster lines with different histories these questions. The were phenotyped for egg-to-adult viability genomes sequenced estimate variation. bacterial 16S rRNA gene was amplified investigate We found 1) host constrained richness 2) core microbiomes low variation constituted from subsets flies higher 3) both diversity contributed 4) connectivity robustness networks the inbred regardless 5) reduced weaker evolutionary responses stressful environments, 6) unrelated Wolbachia density. These findings suggest reduce hologenomic (combined variation). Thus, while current biodiversity crisis focuses on sizes eukaryotes, an additional focal point should carried which turn adaptability consequences persistence populations.

Language: Английский

Continuously fluctuating selection reveals fine granularity of adaptation DOI
Mark C. Bitter, Skyler Berardi,

H. Oken

et al.

Nature, Journal Year: 2024, Volume and Issue: 634(8033), P. 389 - 396

Published: Aug. 14, 2024

Language: Английский

Citations

5
Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation inDrosophila DOI Creative Commons
Heather E. Machado, Alan O. Bergland, Ryan W. Taylor

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2018, Volume and Issue: unknown

Published: June 3, 2018

Abstract To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures seasonal occurring in parallel among Drosophila melanogaster populations. Specifically, estimated allele frequencies genome-wide from flies sampled early and late the growing season 20 widely dispersed We frequency shifts across North America Europe, demonstrating that is a general phenomenon temperate fly Seasonally fluctuating polymorphisms are enriched large chromosomal inversions find broad concordance between spatial change. The direction change at seasonally variable can be predicted by weather conditions weeks prior sampling, linking environment genomic response selection. Our results suggest an important evolutionary force affecting patterns genetic variation .

Language: Английский

Citations

40
Phylosymbiosis across Deeply Diverging Lineages of Omnivorous Cockroaches (Order Blattodea) DOI
Kara Tinker, Elizabeth A. Ottesen

Applied and Environmental Microbiology, Journal Year: 2020, Volume and Issue: 86(7)

Published: Jan. 20, 2020

The gut microbiome plays a key role in host health. Therefore, it is important to understand the evolution of microbiota and how impacts, impacted by, evolution. In this study, we explore relationship between phylogeny composition omnivorous, gregarious cockroaches within Blattodea order, an ancient lineage that spans 300 million years evolutionary divergence. We demonstrate strong species identity found weaker but significant for determining similarity over extended periods time. This study advances our understanding shaping different distances.

Language: Английский

Citations

36
The stability of traits conception of the hologenome: An evolutionary account of holobiont individuality DOI
Javier Suárez

History & Philosophy of the Life Sciences, Journal Year: 2020, Volume and Issue: 42(1)

Published: Feb. 26, 2020

Language: Английский

Citations

36
Population bottlenecks constrain host microbiome diversity and genetic variation impeding fitness DOI Creative Commons
Michael Ørsted, Erika Yashiro, Ary A. Hoffmann

et al.

PLoS Genetics, Journal Year: 2022, Volume and Issue: 18(5), P. e1010206 - e1010206

Published: May 23, 2022

It is becoming increasingly clear that microbial symbionts influence key aspects of their host’s fitness, and vice versa . This may fundamentally change our thinking about how microbes hosts interact in influencing fitness adaptation to changing environments. Here we explore reductions population size commonly experienced by threatened species microbiome diversity. Consequences such are normally interpreted terms a loss genetic variation, increased inbreeding associated depression. However, effects bottlenecks might also be mediated through diversity, as functionally important microbes. utilise 50 Drosophila melanogaster lines with different histories these questions. The were phenotyped for egg-to-adult viability genomes sequenced estimate variation. bacterial 16S rRNA gene was amplified investigate We found 1) host constrained richness 2) core microbiomes low variation constituted from subsets flies higher 3) both diversity contributed 4) connectivity robustness networks the inbred regardless 5) reduced weaker evolutionary responses stressful environments, 6) unrelated Wolbachia density. These findings suggest reduce hologenomic (combined variation). Thus, while current biodiversity crisis focuses on sizes eukaryotes, an additional focal point should carried which turn adaptability consequences persistence populations.

Language: Английский

Citations

22