Lipid Production From Waste Materials in Seawater-Based Medium by the Yeast Yarrowia lipolytica DOI Creative Commons
Adam Dobrowolski, Katarzyna Drzymała, Dorota A. Rzechonek

et al.

Frontiers in Microbiology, Journal Year: 2019, Volume and Issue: 10

Published: March 18, 2019

The global limitation of fossil fuels impels scientists to search for new energy sources. A good alternative is biodiesel produced from crop plants. However, its production requires huge quantities farmland, fertilizers and fresh water, which in conflict with the human demand water consumption land food production. Thus, single cell oil (SCO) by oleaginous microorganisms remains best solution coming years. Whereas most require proper metabolism, this study we demonstrate that unconventional yeast Yarrowia lipolytica able produce fatty acid seawater-based medium. Here shown Y. acids medium based on seawater crude glycerol as main carbon source, allows low-cost SCO, beneficial industrial application ecologically friendly.

Language: Английский

An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications DOI Open Access

Uday Hossain,

Abhishek Das, Sumit Ghosh

et al.

Food and Chemical Toxicology, Journal Year: 2020, Volume and Issue: 145, P. 111738 - 111738

Published: Sept. 9, 2020

Language: Английский

Citations

291
Natural Sweeteners: The Relevance of Food Naturalness for Consumers, Food Security Aspects, Sustainability and Health Impacts DOI Open Access
Ariana Saraiva, Conrado Carrascosa, Dele Raheem

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(17), P. 6285 - 6285

Published: Aug. 28, 2020

At a moment when the population is increasingly aware and involved in what it eats, both consumers food sector are showing more interest natural foods. This review work discusses, addresses provides details of most important aspects consumer’s perceptions attitudes to foods in-depth research into sweeteners. It also includes issues about their use development as regards health impacts, security sustainability. In line with our main outcome, we can assume that very keen on choosing clean labelling, ingredients, preferably other functional properties, without loss taste. response such phenomenon, industry offers alternative sweeteners advantage added benefits. noteworthy Nature superb source desirable substances, many have sweet taste, still need be studied. Finally, must stress being does not necessarily guarantee market success.

Language: Английский

Citations

156
Erythritol: An In-Depth Discussion of Its Potential to Be a Beneficial Dietary Component DOI Open Access
Tagreed A. Mazi, Kimber L. Stanhope

Nutrients, Journal Year: 2023, Volume and Issue: 15(1), P. 204 - 204

Published: Jan. 1, 2023

The sugar alcohol erythritol is a relatively new food ingredient. It naturally occurring in plants, however, produced commercially by fermentation. also endogenously via the pentose phosphate pathway (PPP). Consumers perceive as less healthy than sweeteners extracted from including sucrose. This review evaluates that perspective summarizing current literature regarding erythritol's safety, production, metabolism, and health effects. Dietary 30% sweet sucrose, but contains negligible energy. Because it almost fully absorbed excreted urine, better tolerated other alcohols. Evidence shows has potential beneficial replacement for diabetic subjects exerts no effects on glucose or insulin induces gut hormone secretions modulate satiety to promote weight loss. Long-term rodent studies show consumption lowers body adiposity. However, observational indicate positive association between plasma obesity cardiometabolic disease. unlikely dietary mediating these associations, rather they reflect dysregulated PPP due impaired glycemia glucose-rich diet. long-term clinical trials investigating of chronic risk metabolic diseases are needed. Current evidence suggests will document compared caloric sugars allay consumer misperceptions.

Language: Английский

Citations

51
The dynamic analysis of non-targeted metabolomics and antioxidant activity of Dendrobium officinale Kimura et Migo by the synergistic fermentation of bacteria and enzymes DOI Creative Commons

Jing Wu,

Tao He,

Zhenzhen Wang

et al.

LWT, Journal Year: 2024, Volume and Issue: 203, P. 116354 - 116354

Published: June 15, 2024

The fermentation metabolites of Dendrobium officinale Kimura et Migo (D. officinale) exists a crucial influence on its antioxidant activity which further affects the comprehensive utilization D. products. In this research, multiple proteases were selected for synergistic with Lactobacillus plantarum and Saccharomyces cerevisiae. GC-MS-based untargeted metabolomics was employed to analyze metabolite characteristics predict metabolic pathways fermented liquid (FDL). vitro chemical assay cellular oxidative stress model evaluate FDL. contents phenols, flavonoids B vitamins significantly increased during bacteria enzymes. A total 45 key differential identified, consisting primarily 16 sugars, 15 organic acids 5 polyols. Furthermore, changes in their types shaped by 6 critical pathways. As progressed, scavenging capability FDL free radicals notably augmented, it had ability enhance intracellular enzymes suppressing generation ROS MDA. beneficial exhibited efficient activity.

Language: Английский

Citations

22
A review of polyols – biotechnological production, food applications, regulation, labeling and health effects DOI
Tom Rice, Emanuele Zannini, Elke K. Arendt

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2019, Volume and Issue: 60(12), P. 2034 - 2051

Published: June 18, 2019

Food research is constantly searching for new ways to replace sugar. This due the negative connotations of sugar consumption on health which has driven consumer demand healthier products and reflected a national level by taxation sugary beverages. Sugar alcohols, class polyols, are present in varying levels many fruits vegetables also added foods as low calorific sweeteners. The most commonly used polyols food include sorbitol, mannitol, xylitol, erythritol, maltitol, lactitol isomalt. Of these, microorganisms can produce xylitol erythritol either naturally or through genetic engineering. Production microbes been focus lot its potential an alternative current industrial scale production chemical synthesis but be situ natural sweeteners fermented using approved use foods. review generation these sweetening compounds examines understanding methods microbial that applicable industry. considers benefits effects polyol usage discusses regulations use.

Language: Английский

Citations

145
Aseptic production of citric and isocitric acid from crude glycerol by genetically modified Yarrowia lipolytica DOI
Dorota A. Rzechonek, Adam Dobrowolski, Waldemar Rymowicz

et al.

Bioresource Technology, Journal Year: 2018, Volume and Issue: 271, P. 340 - 344

Published: Sept. 23, 2018

Language: Английский

Citations

96
Sugar Alcohols and Organic Acids Synthesis in Yarrowia lipolytica: Where Are We? DOI Creative Commons
Patrick Fickers, Hairong Cheng, Carol Sze Ki Lin

et al.

Microorganisms, Journal Year: 2020, Volume and Issue: 8(4), P. 574 - 574

Published: April 15, 2020

Sugar alcohols and organic acids that derive from the metabolism of certain microorganisms have a panoply applications in agro-food, chemical pharmaceutical industries. The main challenge their production is to reach productivity threshold allow process be profitable. This relies on construction efficient cell factories by metabolic engineering development low-cost processes using industrial wastes or cheap widely available raw materials as feedstock. non-conventional yeast Yarrowia lipolytica has emerged recently potential producer such metabolites owing its low nutritive requirements, ability grow at high densities bioreactor ease genome edition. review will focus current knowledge synthesis most important sugar Y. lipolytica.

Language: Английский

Citations

71
Mannitol: physiological functionalities, determination methods, biotechnological production, and applications DOI
Ming Chen, Wenli Zhang, Hao Wu

et al.

Applied Microbiology and Biotechnology, Journal Year: 2020, Volume and Issue: 104(16), P. 6941 - 6951

Published: June 29, 2020

Language: Английский

Citations

71
Yarrowia lipolytica as an Alternative and Valuable Source of Nutritional and Bioactive Compounds for Humans DOI Creative Commons
Monika Elżbieta Jach, Anna Malm

Molecules, Journal Year: 2022, Volume and Issue: 27(7), P. 2300 - 2300

Published: April 1, 2022

Yarrowia lipolytica, an oleagineous species of yeast, is a carrier various important nutrients. The biomass this yeast extensive source protein, exogenous amino acids, bioavailable essenctial trace minerals, and lipid compounds as mainly unsaturated fatty acids. also contains B vitamins, including vitamin B12, many other bioactive components. Therefore, Y. lipolytica can be used in food supplements for humans safe nutritional additives maintaining the homeostasis organism, vegans vegetarians, athletes, people after recovery, at risk deficiencies.

Language: Английский

Citations

60
Hydrodeoxygenation of potential platform chemicals derived from biomass to fuels and chemicals DOI
Keiichi Tomishige, Mizuho Yabushita, Ji Cao

et al.

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(15), P. 5652 - 5690

Published: Jan. 1, 2022

This review summarizes a variety of catalytic systems to achieve the selective hydrodeoxygenation potent biomass-derived platform chemicals with focus on features including performance, active sites, and mechanism.

Language: Английский

Citations

53