Green synthesis and Characterization of Acacia nilotica derived silver nanoparticles and their insecticidal potential against three important mosquito vectors DOI Creative Commons

R. Bruntha,

S Lokeshwaran,

Subramanian Panchu Ravindra Rajan Subala

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

Abstract In the present study, bark extract of Acacia nilotica plant was used to green synthesis and Characterization Silver nanoparticles check their insecticidal potential against three important mosquito vectors such as Aedes aegyptii, Anopheles stephensi Culex quinquefasciatus. Our research aims investigate therapeutic combined with nanoparticles. The synthesized silver were characterized by UV-Visible spectroscopy (UV-Vis), Fourier transform infrared Spectroscopy (FT-IR), scanning electron microscopy (SEM) EDax techniques (EDAX) X-ray diffraction (XRD). UV-Vis confirms peak at 420 nm showed SEM spherical shape EDAX revealed chemical components Ag, N, Oxygen a strong elemental signal in association distinct for Ag confirmed 3.15keV. XRD determined crystalline properties (AgNP). antioxidant using AgNP DPPH, hydroxyl ABTS free radical scavenging assays. DPPH activities highest inhibition 63% 84%, while analysis 58%. Antibacterial activity shows level S. pyrogens, P. aeruginosa P.vulgaris. Larvicidal AgNPs recorded good mortality rate aegypti., Anopheles stephensi., Culex This study maximum acts larvicidal, adulticidal, antimicrobial, agents.

Language: Английский

New Insights into the Latest Advancement in α-Amylase Inhibitors of Plant Origin with Anti-Diabetic Effects DOI Creative Commons
Hamdy Kashtoh, Kwang-Hyun Baek

Plants, Journal Year: 2023, Volume and Issue: 12(16), P. 2944 - 2944

Published: Aug. 14, 2023

The rising predominance of type 2 diabetes, combined with the poor medical effects seen commercially available anti-diabetic medications, has motivated development innovative treatment approaches for regulating postprandial glucose levels. Natural carbohydrate digestion enzyme inhibitors might be a viable option blocking dietary absorption fewer side than manufactured medicines. Alpha-amylase is metalloenzyme that facilitates by breaking down polysaccharides into smaller molecules such as maltose and maltotriose. It also contributes to elevated blood levels hyperglycemia. As result, scientists are being urged target α-amylase create can slow release from chains prolong its absorption, thereby resulting in lower plasma derived plants have gained popularity safe cost-effective alternatives. bioactive components responsible inhibitory actions various plant extracts been identified through phytochemical research, paving way further application. majority findings, however, based on vitro investigations. Only few animal experiments very human investigations confirmed these findings. Despite some promising results, additional investigation needed develop feasible drugs plant-derived pancreatic inhibitors. This review summarizes most recent findings research inhibitors, including compounds. Furthermore, it offers insights structural aspects crucial therapeutic target, α-amylases, addition their interactions

Language: Английский

Citations

59
Plant polysaccharides: sources, structures, and antidiabetic effects DOI
Haitao Wang, Hongliang Li,

Yitong Hou

et al.

Current Opinion in Food Science, Journal Year: 2023, Volume and Issue: 51, P. 101013 - 101013

Published: Feb. 23, 2023

Language: Английский

Citations

32
Regulation of glycose and lipid metabolism and application based on the colloidal nutrition science properties of konjac glucomannan: A comprehensive review DOI

Pengkui Xia,

Ying Zheng, Li Sun

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 331, P. 121849 - 121849

Published: Feb. 1, 2024

Language: Английский

Citations

10
Effects of ultrasonic-enzymatic-assisted ethanol precipitation method on the physicochemical characteristics, antioxidant and hypoglycemic activities of Tremella fuciformis polysaccharides DOI Creative Commons
Yixuan Li, Yan He, Hua Zhang

et al.

Ultrasonics Sonochemistry, Journal Year: 2023, Volume and Issue: 101, P. 106682 - 106682

Published: Nov. 6, 2023

This investigation involved the extraction of a novel polysaccharide from spore fermentation broth Tremella fuciformis using method that combined ultrasonic and enzymatic assistance with ethanol precipitation. It was then compared methods. The objective this research is to offer reference point for expanding application ultrasonic-assisted technology in T. polysaccharides (TFPs). Based on single-factor experiments, Box-Behnken used optimize conditions TFPs by ultrasonic-enzymatic-assisted precipitation extraction. results revealed an optimal combination enzymes, cellulase-to-papain ratio 2:1, enzyme addition 4000U/100 mL, enzymolysis temperature 49 °C, ultrasonicpower at 3 W/mL ultrasonictime 20 min. rate α- amylase inhibition rates were 23.94 % 61.44 %, respectively. Comparing physicochemical properties, structural characterization vitro activity extracted through different methods, showed treatment significantly influences apparent morphology could enhance its biological activity. However, techniques exhibit insubstantial impact chemical composition, glycosidic bonds or ring configurations within polysaccharides. Among them, has highest lowest viscosity. significant effects ABTS+ scavenging activity, glucose dialysis retardation index, treated ultrasonic-enzymatic best performance. These findings suggest can activities TFPs, thereby providing valuable insight their future development application.

Language: Английский

Citations

18
Unveiling the breadmaking transformation: Structural and functional insights into Arabinoxylan DOI
Meng Xiao,

Xing Jia,

Ji Kang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 330, P. 121845 - 121845

Published: Jan. 23, 2024

Language: Английский

Citations

7
Natural polysaccharides: The potential biomacromolecules for treating diabetes and its complications via AGEs-RAGE-oxidative stress axis DOI
Jie Sun, Na Wei, Chenxi Yu

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 143, P. 113426 - 113426

Published: Oct. 30, 2024

Language: Английский

Citations

4
Effect of ultrasonic modification on physicochemical properties and bioactivity of polysaccharides from mycelium of Sanghuangporus vaninii DOI
Nengbin Gao, Jingxuan Wang,

Shuang Zhao

et al.

Journal of Food Measurement & Characterization, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Language: Английский

Citations

0
Ultrasonic/microwave-assisted extraction and properties of polysaccharides from Elaeagnus angustifolia DOI
Jinfeng Li, Yan Chen, Yan Qi

et al.

Preparative Biochemistry & Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: Jan. 31, 2025

This study aimed to optimize the ultrasonic/microwave-assisted extraction (UAME) technique of Elaeagnus angustifolia polysaccharides (EAP-UM) by response surface methodology (RSM). The optimum conditions include: solid-liquid ratio 1:23 g/mL, ultrasonic power 252 W, microwave 417 and time 11 min. Under these conditions, yield reached 7.87%, superior ultrasound-assisted (UAE, 5.74%), microwave-assisted (MAE, 6.86%), hot water (HWE, 4.91%). UAME could also result in higher carbohydrate, protein, uronic acid contents compared other methods. properties EAP-UM were further analyzed infrared spectra (IR) scanning electron microscopy (SEM). Moreover, exhibited a remarkable free radical scavenging ability (DPPH, IC50, 79 µg/mL) reduced power. showed α-amylase inhibiting activity (IC50, 2.826 mg/mL). has advantage high rate short time, obtained polysaccharide had better properties. These findings may serve as reference for development application E. angustifolia.

Language: Английский

Citations

0
Hydrogen and Methane Detection in Breath in Response to Two Different Types of Dietary Fiber and Its Relationship to Postprandial Glucose Concentration in Obese Patients with Type 2 Diabetes and Normoglycemic Subjects DOI Open Access
И. В. Мисникова, Yulia A. Kovaleva, Svetlana Y Shokur

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 917 - 917

Published: March 6, 2025

Background: The aim of this study was to investigate the relationship between postprandial glycemic levels based on flashmonitoring and production intestinal hydrogen (H2) methane (CH4) gases measurement amount these in exhaled air. Materials Methods: We studied 14 subjects with type 2 diabetes mellitus (T2DM) individuals without (control) two food load tests, including types dietary fiber (inulin guar gum), simultaneous determination air assessment glucose levels. Results: All control group had a significant increase H2. OR for increased patients T2DM 0.17 (95% CI 0.031-0.93, p = 0.043). level H2 breath after lower than normoglycemic subjects. There an inverse correlation maximum rise (r -0.569, 0.034). Patients direct correlations CH4 parameters glycemia lactulose test (p < 0.05). Conclusions: confirmation causal decreased production, more severe may identify new therapeutic targets correction T2DM.

Language: Английский

Citations

0
Larvicidal, bactericidal, antioxidant, hypoglycemic effects and anti-proliferative activity of phyto-synthesized Ag-ZnO nanocomposites using Eranthemum roseum (Vahl) R.Br. leaf extract against Aedes aegypti and Culex quinquefasciatus mosquito vectors DOI Creative Commons

Ramachandran Adhavan,

Kuppusamy Selvam,

Palanisamy Prakash

et al.

Journal of Natural Pesticide Research, Journal Year: 2024, Volume and Issue: 10, P. 100093 - 100093

Published: Aug. 6, 2024

This research is conducted using zinc doped silver nanocomposite on Eranthemum roseum leaf extract. E. has its own medicinal properties due bioactive compounds. Silver and Zinc also to microbial properties. Our work aimed combine nanoparticles with plant extract explore the The synthesized Ag-ZnO NCs characterized X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscopy energy-dispersive (SEM-EDAX) Transmission Electron Microscopy (TEM) analysis. XRD analysis confirms crystal nature of NCs. average shape was obtained SEM as spherical, EDAX confirming presence Ag, Zn Oxygen TEM conforms oval Antibacterial activity shows highest level against K. pneumoniae B. subtilis. DPPH Activity inhibition 52.56 % while ABTS 54.28 %. Hypoglycemic α-amylase α- glucosidase assay good maximum 63 60 Anti-proliferative cancer causing cells in HepG2 human liver line 67.11 Larvicidal potential recorded mortality rate Aedes aegypti Culex quinquefasciatus. study acts Larvicidal, Anti-proliferative, Antioxidant, agents.

Language: Английский

Citations

3