Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: April 17, 2025
Essential
oils,
often
referred
to
as
"liquid
gold,"
are
renowned
for
their
broad
biological
activity.
Ancient
Egyptians
used
essential
oils'
antibacterial
and
antiseptic
effects
preserve
mummies,
ancient
Greeks
olive
oil
sun
protection,
Chinese
oils
treat
wounds.
When
applied
the
facial
skin,
potent
anti-inflammatory,
antioxidant,
pharmacological
characteristics
provide
various
benefits,
including
sunscreen,
skin-whitening,
anti-aging
effects.
This
paper
aims
summarize
application
of
plant
in
skin
whitening,
antioxidant
recent
years,
deeply
analyzes
internal
relationship
between
modern
drug
delivery
system,
expounds
how
overcome
limitations
through
specific
enhance
its
activity
stability,
realize
sustained
release
reduce
potential
toxicity,
also
discusses
positive
on
brain
function
olfactory
pathway,
emphasizes
possible
safety
risks
use
oil,
puts
forward
corresponding
suggestions
use.
Using
keywords
such
"essential
oils,"
"antioxidant,"
"anti-tyrosinase,"
Antibacterial
Effects
anti-inflammatory,"
"anti-anxiety,"
"drug
carrier
systems,"
a
comprehensive
search
was
conducted
PubMed,
CNKI,
Baidu,
Wanfang
databases
articles
from
past
5
years.
Further
screening
performed
select
studies
demonstrating
efficacy
topical
or
external
application.
Various
showed
strong
oxidants,
agents,
anti-inflammatory
skin-whitening
agents.
Combined
with
new
it
not
only
enhances
but
reduces
inherent
defects
volatility,
irritation,
has
targeted
effect.
At
same
time,
integration
into
care
products
can
make
dual
functions
smell
epidermal
system
nourish
repair
maximize
oil.
review
delves
systems,
advocating
broader
natural
resources
technology.
By
strategically
utilizing
we
promote
sustainable
development
global
economy.
However,
extensive
clinical
trials
still
required
evaluate
effectiveness
systems.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(4), P. 1019 - 1019
Published: Feb. 17, 2023
Chronic
obstructive
pulmonary
disease
(COPD)
is
an
irreversible
inflammatory
respiratory
characterized
by
frequent
exacerbations
and
symptoms
such
as
cough
wheezing
that
lead
to
airway
damage
hyperresponsiveness.
The
primary
risk
factor
for
COPD
chronic
cigarette
smoke
exposure,
which
promotes
oxidative
stress
a
general
pro-inflammatory
condition
stimulating
pro-oxidant
pathways
and,
simultaneously,
inactivating
anti-inflammatory
antioxidant
detoxification
pathways.
These
events
cause
progressive
resulting
in
impaired
cell
function
progression.
Treatments
available
are
generally
aimed
at
reducing
the
of
exacerbation.
Failure
regulate
inflammation
results
lung
damage.
In
quest
innovative
treatment
strategies,
phytochemicals,
complex
plant
extracts
agarwood
essential
oil
promising
sources
molecules
with
activity.
However,
their
clinical
use
limited
issues
low
solubility
poor
pharmacokinetic
properties.
can
be
overcome
encapsulating
therapeutic
using
advanced
drug
delivery
systems
polymeric
nanosystems
nanoemulsions.
this
study,
nanoemulsion
(agarwood-NE)
was
formulated
tested
its
potential
extract
(CSE)-treated
BCi-NS1.1
basal
epithelial
cells.
findings
suggest
successful
counteractivity
agarwood-NE
against
CSE-mediated
effects
expression
cytokines
IL-1α,
IL-1β,
IL-8,
GDF-15.
addition,
induced
mediators
IL-10,
IL-18BP,
TFF3,
GH,
VDBP,
relaxin-2,
IFN-γ,
PDGF.
Furthermore,
also
genes
GCLC
GSTP1,
simultaneously
activating
PI3K
pro-survival
signalling
pathway.
This
study
provides
proof
dual
activity
agarwood-NE,
highlighting
enormous
treatment.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(3), P. 683 - 683
Published: Feb. 4, 2025
Insect
infestation
and
microbial,
particularly
mold
contamination,
are
the
major
causes
of
stored
grain
deterioration
during
postharvest
storage,
which
results
in
a
significant
loss
quality
quantity,
formation
toxic
chemicals
such
as
mycotoxins.
Pesticides,
together
with
physical
protection
strategies,
have
been
widely
used
to
control
insects
molds
grains,
but
their
uses
present
environmental
health
problems.
This
has
led
exploration
safer
pesticide
alternatives.
Essential
oils
(EOs)
highly
concentrated
materials
extracted
from
leaves,
stems,
flowers,
seeds,
roots,
fruit
rinds,
resins,
or
barks.
They
multifunctional
due
complex
chemical
composition.
Thus,
EOs
frequently
for
therapeutic,
antimicrobial,
odoriferous,
flavor
properties
wide
range
products
like
medicine,
cosmetics,
foods.
review
provides
comprehensive
information
on
compositions
commonly
food
industry,
factors
influencing
EO
composition,
recent
studies
potential
alternatives
synthetic
pesticides
fungicides
protection.
The
relationship
between
anti-insects
antimicrobial
potentials,
well
current
approaches/technologies
using
preservation,
also
covered.
However,
this
highlights
need
research
development
feasible
affordable
methodologies
apply
effective
encapsulated
storage
settings,
organic
OpenNano,
Journal Year:
2022,
Volume and Issue:
9, P. 100115 - 100115
Published: Dec. 14, 2022
A
huge
number
of
plant-derived
essential
oils
(EOs)
are
reported
to
have
lots
ethnomedicinal
and
biological
properties
with
excellent
antibacterial
activities.
Approximately
three
hundred
EOs
(ajowan,
anise,
basil,
camphor,
chamomile,
clove,
citronella,
coriander,
cumin,
eucalyptus,
lavender,
lemon,
orange,
peppermint,
thyme
oils,
etc.)
documented
under
economic
class
based
on
commercial
pharmaceutical
values.
However,
most
active
crude
their
constituents
like
carvacrol,
eugenol,
geraniol,
linalool,
thymol,
1,8-cineole,
etc.
not
found
in
mainstream
drug
development
modules
due
low
solubility,
poor
bioavailability,
rapid
volatility
profiles,
which
reduce
potency,
half-life,
pharmacokinetics
achieve
the
ideal
drug-ability
profiles.
To
improve
use
via
nanotechnology,
we
first
gathered
more
information
plant
sources,
extraction
methods,
potency
mode
action,
importance
EOs.
Further,
various
nanotechnology
platforms,
such
as
nanocarriers,
nanoemulsions,
liposomes,
cyclodextrins
chemical
structure
conjugation
concept
relevant
examples
were
described.
Technically,
through
optimization
particle
size
morphology
a
platform,
enhance
without
losing
any
sensitive
properties,
easily
penetrate
cross
bacterial
cell
membrane,
protect
from
by
coating
biocompatible
materials,
aqueous
ensure
sustainable
release,
We
hope
that
detailed
analyses
platforms
will
encourage
academic
researchers
antibacterials
overcoming
inadequate
profiles
potent
agents
drugs,
food,
nutrition,
beverages,
packaging,
materials.
Foods,
Journal Year:
2022,
Volume and Issue:
11(23), P. 3756 - 3756
Published: Nov. 22, 2022
Essential
oils
have
unique
functional
properties,
but
their
environmental
sensitivity
and
poor
water
solubility
limit
applications.
Therefore,
we
encapsulated
oregano
essential
oil
(OEO)
in
chitosan
nanoparticles
(CSNPs)
used
tripolyphosphate
(TPP)
as
a
cross-linking
agent
to
produce
(OEO-CSNPs).
The
optimized
conditions
obtained
using
the
Box-Behnken
design
were:
concentration
of
1.63
mg/mL,
TPP
1.27
OEO
0.30%.
OEO-CSNPs
had
particle
size
182.77
±
4.83
nm,
polydispersity
index
(PDI)
0.26
0.01,
zeta
potential
40.53
0.86
mV,
an
encapsulation
efficiency
92.90%.
success
was
confirmed
by
Fourier
transform
infrared
spectroscopy
(FT-IR)
thermogravimetric
analysis
(TGA).
scanning
electron
microscope
(SEM)
showed
that
regular
distribution
spherical
shape.
vitro
release
profile
at
pH
=
7.4
initial
burst
followed
sustained
OEO.
antibacterial
activity
before
after
measured
agar
disk
diffusion
method.
In
conclusion,
can
be
future
food
processing
packaging
applications
because
its
high
biological
excellent
stability
when
encapsulated.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2023,
Volume and Issue:
64(20), P. 6990 - 7003
Published: Feb. 19, 2023
With
higher
standards
in
terms
of
diet
and
leisure
enjoyment,
spices
essential
oils
aromatic
plants
(APEOs)
are
no
longer
confined
to
the
food
industry.
The
(EOs)
produced
from
them
active
ingredients
that
contribute
different
flavors.
multiple
odor
sensory
properties
their
taste
characteristics
APEOs
responsible
for
widespread
use.
research
on
flavor
is
an
evolving
process
attracting
attention
among
scientists
past
decades.
For
APEOs,
which
used
a
long
time
catering
industries,
it
necessary
analyze
components
associated
with
aromas
tastes.
It
important
identify
volatile
assure
quality
order
expand
application.
worth
celebrating
means
by
loss
can
be
retarded
practice.
Unfortunately,
relatively
little
has
been
done
structure
mechanisms
APEOs.
This
also
points
way
future
APEOs.Therefore,
this
paper
reviews
principles
flavor,
identification
pathways
humans
Moreover,
article
outlines
increasing
efficiency
using
Finally,
respect
applications
review
focuses
practical
application
sector
aromatherapy.
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(4), P. e14985 - e14985
Published: March 31, 2023
Plants
from
the
Asteraceae
family
are
widely
used
as
ethno
medicines
to
treatment
parasitic,
malaria,
hematemesis,
pruritus,
pyretic,
anthelmintic,
wound
healing.
The
aim
of
this
review
is
provide
an
overview
plants
antimicrobial
activity.
most
relevant
results
published
studies
summarized
and
discussed.
species
in
genus
Artemisia,
Echinacea,
Centaurea,
Baccharis,
Calendula
showed
Most
these
usually
treat
infection,
inflammation,
parasitics.
effective
part
or
component
for
was
essential
oil
crude
extract,
attracted
more
attention.
It
also
reported
that
nanoparticles
coated
with
extract
were
against
multidrug
resistant
bacteria.
For
bacteria
study,
Armtemisia
investigated,
Staphylococcus
aureus
Escherichia
coli
studied
strains.
activity
evaluated
mainly
based
on
minimum
inhibitory
concentration
(MIC).
Few
reports
have
been
bactericide
(MBC)
its
antibacterial
mechanisms.
According
study
results,
some
potential
be
developed
bacteriostatic
agents
However,
still
vitro,
further
clinical
applied
needed.
Journal of Agricultural Production,
Journal Year:
2024,
Volume and Issue:
5(1), P. 55 - 72
Published: March 31, 2024
"Nano",
which
derives
from
the
Latin
word
nanus
and
means
dwarf,
refers
to
a
very
small
unit
of
measurement
equal
one
billionth
meter.
Nanotechnology,
deals
with
manipulation
matter
at
atomic
molecular
level,
has
an
application
area
in
animal
husbandry
as
well
many
fields.
Nano-sized
feed
additives,
have
come
forefront
livestock
sector
recent
years,
become
innovative
used
increase
nutritional
value
feeds
optimize
health
performance.
Since
these
additives
are
nano-sized
particles
increased
specific
surface
area,
they
can
positive
effect
on
number
factors
such
digestibility,
nutrient
absorption,
immune
system,
growth
development.
Minerals
form
nanoparticles
bioavailability
by
passing
through
intestinal
wall
body
cells
faster
compared
larger
particles.
The
nano
level
substance
not
only
increases
productivity
animals,
but
also
brings
potential
improve
functionality
molecules.
Nano
digestion
absorption
feed,
allowing
animals
benefit
more
effectively.
However,
there
several
challenges
associated
this
approach.
These
include
for
endotoxin
production,
reduced
due
interaction
natural
nutrients,
possibility
nanoparticle
accumulation
body,
risks,
ethical
considerations,
environmental
concerns
some
negative
effects
interference
nutrients
that
be
avoided
encapsulation.
This
article
discusses
studies
offer
benefits
nutrition.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(7), P. 625 - 625
Published: July 4, 2024
In
the
current
era
of
widespread
antimicrobial
resistance,
utilization
essential
oils
(EOs)
derived
from
plants
has
emerged
as
a
promising
alternative
in
combating
pathogens
that
have
developed
resistance
to
antibiotics.
This
review
explores
therapeutic
potential
valuable
tools
restoring
efficacy
antibiotics,
highlighting
their
unique
ability
affect
bacteria
multiple
ways
and
target
various
cellular
systems.
Despite
challenge
elucidating
precise
mode
action,
EOs
shown
remarkable
results
rigorous
testing
against
diverse
range
bacteria.
multifaceted
role
bacterial
microorganisms,
emphasizing
extraction
methods,
mechanisms
comparative
synthetic
Key
findings
underscore
strategies
deploy
counter
bacteria,
significant
differences
conventional
The
extends
advanced
coating
solutions
for
medical
devices,
exploring
integration
EO
formulations
into
these
coatings.
Challenges
developing
effective
coatings
are
addressed,
along
with
innovative
approaches
implementation.
An
evaluation
reveals
formidable
alternatives
traditional
antibacterial
agents
device
applications.
renaissance
natural
remedies
emphasizes
need
combine
wisdom
modern
scientific
advancements
address
urgent
post-antibiotic
era.
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Aug. 10, 2024
Antibiotics
in
poultry
feed
to
boost
growth
performance
are
becoming
increasingly
contentious
due
concerns
over
antimicrobial
resistance
development.
Essential
oils
(EOs),
as
natural,
plant-derived
compounds,
have
demonstrated
and
antioxidant
properties.
EOs
may
potentially
improve
health
when
included
feed.
Nevertheless,
the
incorporation
of
nutritional
additives
is
hindered
by
their
high
volatility,
low
water
solubility,
poor
intestinal
absorption,
sensitivity
environmental
conditions.
Recently,
nanoencapsulation
strategies
using
nanoformulations
emerged
a
potential
solution
these
challenges,
improving
stability
bioavailability
EOs,
enabling
targeted
delivery
This
review
provides
an
overview
antibacterial
properties
current
limitations
applications
feed,
recent
advancements
nano-engineering
overcome
limitations.
Furthermore,
we
outline
future
research
direction
on
EO
nanoformulations,
emphasizing
promising
role
advancing
sustainable
nutrition.Highlights•
(EOs)
known
powerful
antioxidants
agents.•
replace
antibiotics
additives.•
Nanoformulations
shown
improved
bioactivity
storage
EOs.•
Nanoformulation
promotes
gut
adsorption
additives.