Mycosynthesis and Characterization of Zinc Oxide Nanoparticles from Shiitake Mushrooms (Lentinula edodes): Potential Antidiabetic, Antimicrobial and Antioxidant Efficacy DOI Open Access

M. Yuvarani,

S. Kiruthika,

G. Shiyamala

et al.

Asian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 36(9), P. 2191 - 2196

Published: Aug. 30, 2024

Zinc oxide nanoparticles (ZnO NPs) are widely used because they affordable, reliable and easy to produce. They have special characteristics which render them useful in different medicines. Due their health benefits, affordability minimal impact on the environment, mushrooms a highly favourable option for biomedical applications. In this study, we water-soluble component of methanolic extract Lentinula edodes produce ZnO NPs. The biosynthetic approach utilized flavonoids, polyphenols other constituents from L. edodes, possess reduction encapsulation capabilities, transform metal ions into Various analytical methods, including UV-Vis, FTIR SEM, been characterize biogenic analysis identified presence hydroxyl (OH) group based functional observed at 3425.08 cm–1, moreover, peaks 1631.32 cm–1 indicated C=O carboxylic stretch bonds. Scanning electron microscopy (SEM) demonstrated porous shape with diameters 35-200 nm. biologically produced NPs showed promising antibacterial, antioxidant antidiabetic properties. At specific concentrations, it strong (70.51 ± 0.35%) (82.36 0.41%) effects, indicating that could be therapeutically treatment diabetic conditions suitable incorporation food nutritional supplements.

Language: Английский

Mushrooms in innovative food products: challenges and potential opportunities as meat substitutes, snacks and functional beverages DOI
Alex Graça Contato, Carlos Adam Conte‐Júnior

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 104868 - 104868

Published: Jan. 1, 2025

Language: Английский

Citations

5
Recent advances in Mushroom-mediated nanoparticles: A critical review of mushroom biology, nanoparticles synthesis, types, characteristics and applications DOI
Naheem Adekilekun Tijani, Joseph Hokello, Kehinde Olusayo Awojobi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105695 - 105695

Published: April 21, 2024

Language: Английский

Citations

12
Fungal Biomolecules for Food and Pharmaceutical Application DOI Creative Commons
Giancarlo Angeles Flores, Gaia Cusumano, Gökhan Zengin

et al.

eFood, Journal Year: 2025, Volume and Issue: 6(1)

Published: Jan. 20, 2025

ABSTRACT Mushrooms have long been an integral part of human culture and health are valued for their nutritional therapeutic properties. Often referred to as a superfood, mushrooms rich in bioactive compounds that provide range benefits including antioxidant, antimicrobial, anticancer, prebiotic, antidiabetic, anti‐inflammatory effects. This review focussed on the diversity mushrooms, emphasizing medicinal significance, explores secondary metabolites with potential applications nutraceuticals pharmaceuticals. It underscores role vital agents developing value‐added products. An overview compounds, such polysaccharides, peptides, proteins, terpenoids, phenolic identified numerous mushroom species. Additionally, addresses advancements fungal biotechnology, particularly use fungi efficient industrial cell factories, influence food quality sustainability. By critically analyzing recent studies, summarizes diverse roles biomolecules pharmaceutical industries highlights significant contribution modern medicine health‐related fields.

Language: Английский

Citations

1
Bioactive Secondary Metabolites of Two Chinese Edible Boletes, Phlebopus portentosus and Butyriboletus roseoflavus DOI Creative Commons
Zhixuan Wang, Wei Zhou, Yuhang He

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1197 - 1197

Published: March 7, 2025

This study investigated the phytochemical profiles and bioactivities of two edible boletes from Southwestern China, Phlebopus portentosus Butyriboletus roseoflavus. A total 33 secondary metabolites, comprising 15 alkaloids, 4 pulvinic acid derivative pigments, 14 ergosterols, were isolated identified. To our best knowledge, boletesine (1), B (2), cis-xerocomic (16) previously undescribed compounds. The new structures established by extensive spectroscopic methods chemical calculations. Compound 1 features a hitherto unknown hybrid skeleton formed between 2-formylpyrrole-alkaloid dopacetic (DOPAC) via Michael addition reaction. Bioactivity assays revealed neuroprotective effects compounds 18 19 against Aβ25–35- or H2O2-induced toxicity. In cytotoxic assay small panel cancer cell lines, compound 9 exhibited significant activity HeLa cells (IC50 = 10.76 µM), while demonstrated broad-spectrum cytotoxicity Hela229, SGC7901, PC-3, BEL7402 (IC50s in range 20~30 µM). Of particular note is anti-influenza virus activities A/H3N2 B/Victoria strains 22 26 (EC50 values ranging 3.6 to 9.6 Along with these, 29 showed moderate antiviral effect coxsackievirus B3. These findings underscore therapeutic potential addressing neurodegenerative diseases, cancer, viral infections, paving way for their prospective applications development functional foods pharmaceuticals.

Language: Английский

Citations

1
Bioactive Compounds Produced by Macromycetes for Application in the Pharmaceutical Sector: Patents and Products DOI Creative Commons

Walter José Martínez-Burgos,

Everaldo Montes Montes,

Roberta Pozzan

et al.

Fermentation, Journal Year: 2024, Volume and Issue: 10(6), P. 275 - 275

Published: May 23, 2024

It is widely known that mushrooms present several properties with applications in the medicinal and pharmaceutical sectors, including antimicrobial, immunomodulatory, antioxidant, hypotensive, neuroprotective, anti-inflammatory activities. This article aims to review examples of bioactive metabolites responsible for those activities, such as polysaccharides, phenols polyphenols, terpenes, peptides, alkaloids, steroids, which are produced by relevant mushroom species. also discusses their production through solid-state fermentation submerged fermentation, well processes obtention extracts considerations on stability aiming industrial applications. In addition, examines patent landscape surrounding mushroom-derived bioactives, shedding light intellectual property history innovations driving this field forward. Examples recently deposited patents highlighted, main depositors. China United States major depositor countries (52% 35% patents, respectively), principal compounds polysaccharides alkaloids. The provides insights into current market landscape, showcasing products available consumers. From dietary supplements skincare formulations, offerings reflect growing interest harnessing health benefits bioactives.

Language: Английский

Citations

5
Photoregulation of the biosynthetic activity of the edible medicinal mushroom Lentinula edodes in vitro DOI
Оksana Mykchaylova, Halyna Dubova, A.М. Negriyko

et al.

Photochemical & Photobiological Sciences, Journal Year: 2024, Volume and Issue: 23(3), P. 435 - 449

Published: Jan. 30, 2024

Language: Английский

Citations

4
Impact of Lactic Acid Bacteria Fermentation Based on Biotransformation of Phenolic Compounds and Antioxidant Capacity of Mushrooms DOI Creative Commons
Eda Nur Ayar, Yannick Verheust, Beraat Özçelik

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(11), P. 1616 - 1616

Published: May 23, 2024

Mushrooms contain phenolic compounds that possess health-promoting properties, including antioxidant effects. However, the low solubility and form of affect their bioactivity bioaccessibility. To overcome this limitation, our study investigates fermentation mushrooms to increase free content enhance bioactivity. Our research focused on impact both bound fractions (FPs BPs, respectively) in Lentinula edodes Lactarius deliciosus, which were successively fermented with Lactiplantibacillus plantarum LMG 17673 for 72 h. We examined total (TPC), profile, activity FPs BPs. results showed TPC BPs was higher than mushrooms, strong capabilities. Fermentation significantly increased particularly after 24 h fermentation. The decreased during fermentation, indicating release from matrix. Additionally, we identified 30 bioactive using UPLC-Q-TOF-MS/MS. demonstrates first time lactic acid bacteria high leads liberation phenolics, enhancing

Language: Английский

Citations

4
Physicochemical and phytochemical characterization of opuntia dillenii : A promising source of bioactive compounds DOI Creative Commons

Loukili El Hassania,

Bouslamti Mohammed,

Salma Kadda

et al.

International Journal of Food Properties, Journal Year: 2024, Volume and Issue: 27(1), P. 1079 - 1094

Published: Aug. 4, 2024

The objective of this ongoing research is to investigate and assess the aqueous extracts, vegetable oil, residual plant components derived from O. dillenii by use HPLC, GC-MS. Subsequent investigations employed colorimetric techniques identify reducing soluble sugars. We developed validated an energy-dispersive X-ray fluorescence (EDXRF) method for determining concentrations essential chemical elements (O, C, Ca, Mg, K, S, P) in seeds, juice, peel, as well their residues. HPLC analysis yielded results indicating that extracts peel distinct regions (Oujda, Nador, Essaouira) contained elevated metabolites. Specifically, juice exhibited highest levels organic acids betanin compared seeds. Conversely, seed oils displayed a noteworthy tocopherol content, predominantly δ-tocopherol. Similarly, examination acid composition seeds three different revealed levels. Citric oxalic emerged predominant juice. Overall, Opuntia dillenii's physicochemical phytochemical characterization improves understanding its potential bioactive promoter, which could lead creation new medicinal medicines or functional food ingredients.

Language: Английский

Citations

4
Recent research on the bioactivity of polyphenols derived from edible fungi and their potential in chronic disease prevention DOI Creative Commons

Wenbin Yu,

Yufei Zhang, Yi Lu

et al.

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 124, P. 106627 - 106627

Published: Dec. 12, 2024

Language: Английский

Citations

4
Unearthing Nature’s Pharmacy: Exploring the Antimicrobial Potency of Mushrooms DOI Creative Commons
Mohammed Al Qutaibi, Suresh R. Kagne

Journal of Food Processing and Preservation, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

The search for a new antibiotic or antifungal that could function efficiently without side effects inadequacies was always dilemma. For centuries, mushrooms have been praised their medicinal powers. Recent studies show many mushroom species possess antimicrobial compounds inhibit kill bacteria, fungi, and other microbes. These attributed the potency of to presence active called phytochemicals. Mushrooms found contain an abundance phytochemicals such as phenolics, terpenoids, flavonoids, alkaloids, steroids, saponins, polysaccharides. can cell wall synthesis disrupt membrane permeability redox balance. This review highlights current knowledge about phytochemical content mushrooms, properties, some extraction strategies. various microorganisms, foodborne pathogens, drug‐resistant are discussed. Critical limitations in using sources include safety risks from toxins, variability compound between species, purification challenges, inconsistent yields, scalability issues, regulatory hurdles commercial applications. Overall, this article shows prosperous benefit human health.

Language: Английский

Citations

3