Etiopathology, Epidemiology, Diagnosis, and Treatment of Fungal Keratitis
ACS Infectious Diseases,
Journal Year:
2024,
Volume and Issue:
10(7), P. 2356 - 2380
Published: June 7, 2024
Fungal
keratitis
(FK)
is
a
severe
ocular
condition
resulting
from
corneal
infection
that
prevalent
in
tropical
countries,
particularly
developing
regions
of
Asia
and
Africa.
Factors
like
lens
misuse,
inappropriate
steroid
use,
diagnostic
challenges
have
provoked
the
epidemic.
FK
causes
significant
vision
impairment,
scarring,
deformities.
Accurate
pathological
diagnosis
crucial
for
effective
therapeutic
intervention.
Topical
antifungal
therapy
with
surface
healing
medications
proves
preventing
fungal-borne
ulcers.
Managing
requires
comprehensive
understanding
fungal
pathogenesis,
guiding
formulation
strategies
preventive
measures
to
curb
global
blindness.
This
review
provides
in-depth
insights
into
FK,
covering
etiology,
epidemiology,
interventions,
resistance,
limitations,
prevention,
future
perspectives
on
disease
management.
Language: Английский
Pharmaceutical Emulsions: A Viable Approach for Ocular Drug Delivery
Journal of Ocular Pharmacology and Therapeutics,
Journal Year:
2024,
Volume and Issue:
40(5), P. 261 - 280
Published: April 24, 2024
Ocular
disorders
can
lead
to
serious
sight
impairment
and
irreversible
blindness.
Generally
simple
topical
systemic
treatments
are
recommended
for
treating
these
vision-threatening
illnesses.
The
distinctive
architecture
of
the
eye
complicates
ocular
drug
delivery.
ophthalmic
emulsion
formulations
have
been
found
increase
bioavailability
in
by
prolonging
residence
time
improving
permeability
through
cornea.
Therefore,
this
study
highlights
emulsions
meant
both
anterior
posterior
parts
while
examining
a
wide
range
that
affect
individuals
globally.
This
review
presents,
brief,
recent
emulsion-based
patented
innovations,
clinical
trials,
marketed
delivery,
which
strengthening
development
new
products
managing
different
diseases
disorders.
Language: Английский
Recent updates on ocular disease management with ophthalmic ointments
Therapeutic Delivery,
Journal Year:
2024,
Volume and Issue:
15(6), P. 463 - 480
Published: June 2, 2024
Ophthalmic
diseases
can
result
in
permanent
vision
loss
and
blindness.
Convenient
topical
systemic
treatments
are
preferred
to
address
these
sight-threatening
conditions.
However,
the
unique
anatomy
of
eye
presents
challenges
for
drug
delivery.
Various
ophthalmic
ointment
formulations
have
been
developed
enhance
bioavailability
prolong
residence
time
improve
corneal
permeability.
This
article
explores
a
wide
range
ocular
affecting
individuals
globally
how
ointments
used
manage
them.
From
barriers,
this
review
focuses
on
published
scientific
research
formulation
strategies
severe
complications
using
conventional
ointments.
Additionally,
it
delves
through
patented
technologies
marketed
supporting
use
Language: Английский