EAT‐Lancet Diet Pattern, Genetic Predisposition, Inflammatory Biomarkers, and Risk of Lung Cancer Incidence and Mortality DOI
Fubin Liu,

Changyu Si,

Linlin Chen

et al.

Molecular Nutrition & Food Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 5, 2024

Scope The association between a planetary and sustainable EAT‐Lancet diet lung cancer remains inconclusive, with limited exploration of the role genetic susceptibility inflammation. Methods results study includes 175 214 cancer‐free participants in UK Biobank. Fourteen food components are collected from 24‐h dietary recall questionnaire. A polygenic risk score is constructed through capturing overall variants for cancer. Sixteen inflammatory biomarkers assayed blood samples. Participants highest scores (≥12) have lower incidence (hazard ratio [HR] = 0.64, 95% confidence interval [CI]: 0.51–0.80) mortality (HR 0.65, CI: 0.48–0.88), compared to those lowest (≤8). Interestingly, there significantly protective trend against both adenocarcinoma squamous cell carcinoma higher scores. Despite no significant interactions, reduction observed increasing decreasing risk. Ten partially mediate Conclusion depicts conferred by associated inflammation levels among individuals diverse predispositions.

Language: Английский

Diet strategies for promoting healthy aging and longevity: An epidemiological perspective DOI Creative Commons
Frank B. Hu

Journal of Internal Medicine, Journal Year: 2023, Volume and Issue: 295(4), P. 508 - 531

Published: Oct. 23, 2023

Abstract In recent decades, global life expectancies have risen significantly, accompanied by a marked increase in chronic diseases and population aging. This narrative review aims to summarize findings on the dietary factors influencing longevity, primarily from large cohort studies. First, maintaining healthy weight throughout is pivotal for aging mirroring benefits of lifelong, moderate calorie restriction today's obesogenic food environment. Second, specific types or sources fat, protein, carbohydrates are more important disease risk mortality than their quantity. Third, some traditional diets (e.g., Mediterranean, Nordic, Okinawa) contemporary patterns, such as plant‐based diet index, DASH (dietary approaches stop hypertension) diet, alternate eating been associated with lower longevity. These patterns share many common components predominance nutrient‐rich plant foods; limited red processed meats; culinary herbs spices prevalent cuisines) while embracing distinct elements different cultures. Fourth, combining other lifestyle could extend disease‐free 8–10 years. While adhering core principles diets, it crucial adapt recommendations individual preferences cultures well nutritional needs populations. Public health strategies should aim create healthier environment where nutritious options readily accessible, especially public institutions care facilities elderly. Although further mechanistic studies human trials needed better understand molecular effects aging, there pressing need establish maintain long‐term cohorts studying culturally diverse

Language: Английский

Citations

52
Adherence to the EAT-Lancet diet and risk of coronary events in the Malmö Diet and Cancer cohort study DOI Creative Commons
Shunming Zhang,

Justine Dukuzimana,

Anna Stubbendorff

et al.

American Journal of Clinical Nutrition, Journal Year: 2023, Volume and Issue: 117(5), P. 903 - 909

Published: Feb. 24, 2023

The EAT-Lancet Commission proposed a globally environmentally sustainable dietary pattern featuring mainly plant-based foods in 2019. However, evidence on this preventing coronary events is minimal.We aimed to examine the association between diet and risk of events.The Malmö Diet Cancer cohort study (recruited 1991 1996) included 23,877 participants aged 44.5-73.6 y (62.5% women) without CVDs diabetes at baseline. A modified history was used collect data. An index (range, 0-42 points) applied basis 14 food components scored 0 (nonadherence) 3 (adherence). Coronary were extracted from registers. Cox proportional hazards models estimate HRs 95% confidential intervals (CIs).Over median 24.9 follow-up, 3031 occurred (incidence rate: 5.89/1000 person-years). After adjusting for age, sex, assessment methods, season, total energy intake, leisure-time physical activity, alcohol consumption, smoking status, educational level, BMI, multivariable HR (95% CI) among who had highest adherence (≥23 points, 8.1%) 0.80 (0.67, 0.96) compared with those lowest (≤13 9.7%) (P-trend = 0.01 across 5 groups diet). inverse consistent men women robust after excluding misreported significant changes or within first 2 follow-up.Our data indicate that associated lower events.

Language: Английский

Citations

49
Planetary Health Diet Index and risk of total and cause-specific mortality in three prospective cohorts DOI
Linh Bui, Tung Pham Thanh, Fenglei Wang

et al.

American Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: 120(1), P. 80 - 91

Published: June 12, 2024

Language: Английский

Citations

35
Adherence to the EAT-Lancet reference diet is associated with a reduced risk of incident cancer and all-cause mortality in UK adults DOI Creative Commons
Nena Karavasiloglou, Alysha S. Thompson, Giulia Pestoni

et al.

One Earth, Journal Year: 2023, Volume and Issue: 6(12), P. 1726 - 1734

Published: Nov. 21, 2023

Food systems have been identified as significant contributors to the global environmental emergency. However, there is no universally agreed-upon definition of what constitutes a planetary healthy, sustainable diet. In our study, we investigated association between EAT-Lancet reference diet, diet within boundaries, and incident cancer, major cardiovascular events, all-cause mortality. Higher adherence was associated with lower cancer risk (hazard ratio [HR]continuous: 0.99; 95% confidence interval [CI]: 0.98–0.99]) mortality (HR continuous: 0.98; CI: 0.98–0.99), while mostly null associations were detected for event 1.00; 0.98–1.01). Stratified analyses using potentially modifiable factors led similar results. Our findings, in conjunction existing literature, support that adoption could benefit prevention non-communicable diseases.

Language: Английский

Citations

28
Planetary health diet and cardiovascular disease: results from three large prospective cohort studies in the USA DOI Creative Commons
Caleigh M Sawicki,

G. Ramesh,

Linh Bui

et al.

The Lancet Planetary Health, Journal Year: 2024, Volume and Issue: 8(9), P. e666 - e674

Published: Sept. 1, 2024

Language: Английский

Citations

11
Association between planetary health diet and cardiovascular disease: a prospective study from the UK Biobank DOI Creative Commons
Mercedes Sotos‐Prieto, Rosario Ortolá, Javier Maroto-Rodríguez

et al.

European Journal of Preventive Cardiology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 29, 2024

Abstract Aims The Planetary Health Diet Index (PHDI) prioritizes the well-being of both individuals and planet but has yielded mixed results on cardiovascular disease (CVD). aim this study was to assess association between PHDI risk CVD. Methods A cohort 118 469 aged 40–69 years from UK Biobank, who were free CVD at 2009–12 followed up 2021. calculated using least two 24-h dietary assessments included 14 food groups, with a possible range 0 130 points. Cardiovascular incidence defined as primary myocardial infarction or stroke obtained clinical records death registries. During 9.4-year follow-up, 5257 incident cases ascertained. When comparing highest (89.9–128.5 points) vs. lowest (21.1–71.1 quartile adherence, multivariable-adjusted hazard ratio [95% confidence interval (CI)] 0.86 (0.79, 0.94) for CVD, 0.88 (0.80, 0.97) infarction, 0.82 (0.70, stroke. linear until plateau effect reached 80 points adherence PHDI. Results remained robust when excluding participants type 2 diabetes, including only those three more diet assessments, in first 3 follow-up. group components strongly associated reduced higher consumption whole grains, fruits, fish lower added sugars fruit juices. Conclusion In large middle-aged older British adults, These provide empirical evidence that pattern, thought be environmentally sustainable, benefits health.

Language: Английский

Citations

9
Health and environmental dietary impact: Planetary health diet vs. Mediterranean diet. A nationwide cohort in Spain DOI

Melchor Riera,

Rosario Ortolá, Stefanos N. Kales

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 968, P. 178924 - 178924

Published: Feb. 22, 2025

Language: Английский

Citations

1
Higher adherence to the EAT-Lancet reference diet is associated with higher nutrient adequacy in the NutriNet-Santé cohort: a cross-sectional study DOI
Florine Berthy, Joséphine Brunin, Benjamin Allès

et al.

American Journal of Clinical Nutrition, Journal Year: 2023, Volume and Issue: 117(6), P. 1174 - 1185

Published: April 4, 2023

Language: Английский

Citations

21
The Association of Planetary Health Diet with the Risk of Type 2 Diabetes and Related Complications: A Systematic Review DOI Open Access
Omorogieva Ojo,

Yiqing Jiang,

Osarhumwese Osaretin Ojo

et al.

Healthcare, Journal Year: 2023, Volume and Issue: 11(8), P. 1120 - 1120

Published: April 13, 2023

Background: Nutritional interventions such as the planetary health diet, which EAT-Lancet commission proposed, may be an effective strategy for reducing type 2 diabetes risks and its associated complications. The diet demonstrates significant role of in associating human with environmental sustainability significance transforming food systems order to ensure that UN’s Sustainable Development Goals Paris Agreement are achieved. Therefore, aim this review is examine association (PHD) risk related Method: systematic was conducted line established guidelines. searches were carried out sciences research databases through EBSCOHost. population, intervention, comparator outcomes framework used define question search terms. from inception 15 November 2022. Search terms including synonyms medical subject headings combined using Boolean operators (OR/AND). Results: Seven studies included four themes identified, incidence diabetes; cardiovascular factors other disease risks; indicators obesity sustainability. Two examined between PHD found high adherence reference (EAT-Lancet diet) correlated a lower diabetes. High also some Conclusion: This has shown reduced subarachnoid stroke. In addition, inverse relationship markers Adherence values risk. More needed fully conditions.

Language: Английский

Citations

20
Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and Planet DOI Open Access
Susan L. Prescott, Christopher R. D’Adamo, Kathleen F. Holton

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(15), P. 6461 - 6461

Published: July 27, 2023

Global food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is dramatic global spread ultra-processed convenience foods last 75 years, which linked with rising human burden disease growing sustainability environmental challenges. However, there also calls to radically transform systems, from animal plant-derived protein sources, may have unintended consequences. Commercial entities moved toward this "great plant transition" vigor. Whether motivated by profit or genuine concern, effort has facilitated emergence novel "plant-based" commercial products devoid nutrients fiber, sometimes inclusive high sugar, industrial fats, synthetic additives. These other ingredients combined into often assumed be healthy lower calorie content. available evidence indicates that many these can potentially compromise at all scales-of people, places, planet. In viewpoint, we summarize reflect on discussions presented Nova Network meeting "Future Food", had particular focus encroachment supply, including plant-sourced alternatives (and collective therein) finding their way fast-food chains. We contend while been much uncritical media attention given impact macronutrient sources-meat vs. soy/pea burgers, etc.-the heavy processing both significant but overlooked, effects cognition mental health. This more nuanced discourse considers complexities refocuses priorities value towards mutualistic solutions, co-benefits individuals, local communities, ecology.

Language: Английский

Citations

18