Research Square (Research Square),
Journal Year:
2022,
Volume and Issue:
unknown
Published: Aug. 9, 2022
Abstract
Background
:
Deprescribing
is
a
planned
and
supervised
process
of
reducing,
substituting,
or
discontinuing
medicines
that
are
unnecessary
deemed
to
be
harmful
tailored
individual
patient
needs.
The
study
aimed
assess
the
knowledge,
attitude,
practice
healthcare
providers
towards
deprescribing
in
Ambo
university
referral
hospital
(AURH)
AGH
(Ambo
general
hospital),
Ethiopia
identify
perceived
barriers
enablers
deprescribing.
Methods:
A
self-administered
structured
questionnaire
was
used
collect
information
from
with
facilities
based
cross-sectional
design
July
September
2021.
data
cleaned,
coded,
entered
into
SPSS
version
25
statistical
software
for
analysis.
Descriptive
statistics
were
describe
finding.
Results
Two
hundreds
twenty
three
(223)
health
care
AURH
took
part
study.
Among
participants,
155(69.5%)
heard
about
but
125(56.1%)
reportedly
had
insufficient
knowledge
More
than
fourth
respondents
(75.8%)
agreed
does
benefits
harms
patients
terms
decreasing
pills
burden,
cost
medication,
drug-drug
interaction,
improving
overall
treatment
outcomes
quality
life.
One
forty-seven
(65.9%)
reported
they
consciously
practiced
Respondents
149
(66.8%)
them
deprescribed
antipsychotic
which
followed
by
antidepressant
142(63.7%)
antihypertensive
112(50.2%)
medications.
noted
engagement
pharmacists
83
(37.2%),
existence
evidence
user-friendly
guidelines
78(34.9%),
having
sufficient
57
(
25.6%)
effective
multidisciplinary
team
collaboration
communication
51
(22.9%)
most
often
practicing
On
other
hand,
lack
organizational
support
85(38.1%),
clear
risk-benefit
regarding
75(33.6%),
time
constraint
access
evidence-based
54(24.2%)
frequently
barriers.
Conclusion
half
three-fourth
patients.
In
general,
identified
interconnected
patient-related,
provider-related,
system-related
Therefore,
multi-level
approach
through
innovations
initiatives
should
sought
address
BMJ Open,
Journal Year:
2025,
Volume and Issue:
15(1), P. e095584 - e095584
Published: Jan. 1, 2025
Objective
To
map
instruments
for
assessing
healthcare
professionals’
knowledge,
attitudes
and
practices
regarding
deprescribing.
Introduction
Deprescribing
is
essential
improving
patient
outcomes
by
managing
polypharmacy,
reducing
fall
risks
decreasing
medication
costs.
However,
there
a
limited
exploration
of
perspectives
about
Methods
analysis
Studies
involving
professionals
directly
involved
in
the
use
process
(nurses,
pharmacists
physicians)
will
be
included,
while
those
which
it
not
possible
to
identify
professional
excluded.
Any
definition
deprescribing,
as
well
any
stage
deprescribing
process,
without
clear
employing
whether
validated
or
not,
included.
focusing
on
algorithms
setting
Data
presented
absolute
relative
frequencies,
world
heatmap,
heatmaps,
bar
plots
word
cloud
when
appropriate.
Ethics
dissemination
The
findings
from
this
review
discussed
with
stakeholders
processes.
Additionally,
results
disseminated
through
publications
conference
presentations.
Protocol
registration
https://osf.io/tgjyc/
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0316363 - e0316363
Published: Jan. 30, 2025
There
is
paucity
of
studies
focused
on
the
enablers
and
barriers
to
community
pharmacists’
readiness
deprescribe
inappropriate
medications
for
older
adults
in
developing
settings.
The
current
study
assessed
implement
deprescribing
adults.
A
cross-sectional
survey
252
pharmacists
was
conducted
Qatar
with
a
pre-tested
24-item
questionnaire
developed
theory
domain
framework.
Information
about
perceived
were
elicited
5-point
Likert-type
scale.
response
rate
79.4%
(200/252).
majority
females
(54.5%),
within
age
range
20–40
years
(88.0%),
had
BSc
/
BPharm
as
highest
educational
qualification
(70.5%),
full-time
employee
(97.0%).
top-ranked
exposure
CPD
use
toolkits
algorithm
(66%),
interprofessional
collaboration
physicians
(60.5%)
shared
electronic
patient
record
(59.5%),
improved
remuneration
re-imbursement
58%).
lack
access
records
ineffective
(66.5%),
time
due
heavy
workload
(65%),
regulatory
framework
that
limit
expansion
clinical
roles
(51%)
intense
focus
sales
target
(49%).
algorithm,
record.
These
findings
bode
well
implementation
pharmacists-led
Qatar.
However,
number
critical
identified,
these
will
require
institutional,
organizational
interventions
improve
readiness.
Pharmacy,
Journal Year:
2024,
Volume and Issue:
12(4), P. 116 - 116
Published: July 24, 2024
Non-steroidal
anti-inflammatory
drugs
(NSAIDs)
are
largely
used
for
controlling
various
pain
conditions
and
widely
available
in
community
pharmacies,
with
without
prescription.
Despite
their
effectiveness,
NSAIDs
can
pose
significant
risks
due
to
potential
side
effects
drug
interactions,
particularly
polypharmacy
comorbidity
contexts
vulnerable
users.
This
study
investigated
whether
how
deprescribing
be
conducted
at
the
pharmacy
level
by
assessing
pharmacists'
confidence,
attitudes,
barriers
facilitators.
Additionally,
we
aimed
identify
any
guidelines
that
pharmacists
could
use.
A
literature
search
a
cross-sectional
digital
questionnaire
targeting
Norway
were
conducted.
Results
showed
participants
(N
=
73)
feel
confident
identifying
needs
but
such
as
time
constraints,
lack
of
financial
compensation,
communication
challenges
noted.
Participants
reported
positive
attitudes
toward
highlighted
need
better
training.
highlights
gap
specific
enhancing
roles
process,
example,
through
training
improved
incentives.
Further
research
is
encouraged
develop
concrete
strategies
an
effective
implementation
where
involved
NSAIDs.
European Geriatric Medicine,
Journal Year:
2022,
Volume and Issue:
13(6), P. 1455 - 1466
Published: Nov. 2, 2022
To
provide
an
overview
of
the
current
deprescribing
attitudes,
practices,
and
approaches
geriatricians
geriatricians-in-training
across
Europe.An
online
survey
was
disseminated
among
European
geriatricians-in-training.
The
comprised
Likert
scale
multiple-choice
questions
on
education
knowledge,
facilitators/barriers
deprescribing.
Responses
to
participant
characteristics
were
quantified
differences
evaluated
between
regions.The
964
respondents
(median
age
42
years
old;
64%
female;
21%
geriatricians-in-training)
generally
willing
deprescribe
(98%)
felt
confident
about
(85%).
Despite
regions,
most
commonly
reported
reasons
for
functional
impairment
occurrence
adverse
drug
reactions.
important
barriers
patients'
unwillingness,
fear
negative
consequences,
lack
time,
poor
communication
multiple
prescribers.
Perceived
risk
reactions
highest
psychotropic
drugs,
nonsteroidal
anti-inflammatory
cardiovascular
opioid
analgesics.
Only
one
in
four
(23%
37%
think
medical
school
had
sufficiently
prepared
them
clinical
practice.
They
that
their
future
activities
would
probably
increase
with
improved
information
sharing
various
prescribers,
recommendations
guidelines,
increased
training.
Approximately
90%
a
paradigm
shift
is
required
prescribers
patients,
increasing
focus
possible
benefits
(potentially)
inappropriate
medications.Based
outcomes
this
survey,
we
recommend
investing
inter-professional
communication,
better
evidence-based
improve
patient-centered
practices.
International Journal of Pharmacy Practice,
Journal Year:
2023,
Volume and Issue:
31(4), P. 387 - 395
Published: April 28, 2023
Deprescribing
is
a
novel
strategy
whereby
medical
professionals
aim
to
optimize
patient's
prescription
program
by
removing
redundant
medications.
Few
studies
have
looked
at
the
viewpoints
of
community
pharmacists
and
other
healthcare
on
deprescribing
in
daily
practice.
This
study's
objectives
included
evaluating
pharmacists'
knowledge,
attitudes
practices,
as
well
identifying
obstacles
enablers
practice.Five
pharmacy
students
last
year
their
polled
employees
neighbourhood
pharmacies
Abu
Dhabi,
Dubai,
Northern
Emirates
from
April
2022
July
2022.
The
questionnaire
was
divided
into
two
sections:
questions
that
inquired
about
respondents'
demographic
data
evaluated
understanding
usage
potentially
harmful
medications
for
patients.
original
Bloom's
cutoff
points
were
revised
modified
assess
general
knowledge
practices
United
Arab
(UAE)
pharmacists.
Multivariate
logistic
regression
identified
variables
influencing
practice.The
average
age
participants
30.8
±
6.4
SD.
Of
total,
255
(37.7%)
male
422
(62.3%)
female.
Pharmacists
independent
constituted
52.9%
study
sample
47.1%
Chain
pharmacies.
Among
participants,
58.8%
(n
=
398)
had
1-5
years
experience
41.2%
279)
more
than
5
years.
Nearly
three-quarters
(72.1%,
488)
graduated
local
universities
27.9%
189)
regional/international
universities.
vast
majority
(84.8%,
574)
bachelor's
degree
holders
88.3%
598)
charge.
69.3%
469)
received
training
treat
patients
with
multimorbid
diseases.
practice
score
71.3%
95%
confidence
interval
[70.2%,
72.4%].
total
113
(16.7%)
poor
deprescribing,
393
(58.1%)
moderate
171
(25.3%)
good
practice.This
highlights
level
UAE.
Although
most
respondents
this
less
half
unaware
certain
classes
(long-acting
sulfonylureas,
anti-diabetic,
antihyperlipidemic
psychotropic
drugs)
drugs
are
candidates
potential
deprescribing.
finding
indicates
insufficient.
Several
barriers
face
also
identified,
patients'
resistance
insufficience
being
prevalent.
Therefore,
there
need
improved
ensure
drug
safety.
PLoS ONE,
Journal Year:
2022,
Volume and Issue:
17(12), P. e0274552 - e0274552
Published: Dec. 15, 2022
The
prevalence
of
polypharmacy
increases
with
age,
increasing
the
exposure
older
adults
to
potentially
inappropriate
medications
(PIMs).
Deprescribing
has
been
shown
reduce
PIMs
for
residents
in
long-term
care;
however,
deprescribing
is
not
universally
implemented.
This
study
aims
identify
barriers
and
enablers
Irish
care
facilities
from
healthcare
professionals'
(HCPs)
perspective.A
qualitative
descriptive
approach
was
conducted
using
semi-structured
interviews
HCPs
working
(general
practitioners,
pharmacists
nurses).
Purposive
sampling
maximum
variation
applied
select
sites
HCPs,
supplemented
convenience
post-graduate
University
College
Cork.
Data
thematically
analysed
mapped
a
framework
informed
by
Theoretical
Domains
Framework.Twenty-six
participated
13
facilities.
main
identified
five
domains.
Barriers
included
insufficient
resources,
lack
co-ordination
between
settings
negative
social
influences.
Additional
exist
private
including
awareness,
commitment
need
incentives.
interprofessional
support
patient
influence.
To
encourage
deprescribing,
potential
include
HCP
education,
pharmacist
role
expansion
tailored
guidelines
within
structured
process.Interventions
should
build
on
existing
systems,
involve
stakeholders
utilise
process.
Any
intervention
must
account
nuanced
which
both
public
settings.
Research in Social and Administrative Pharmacy,
Journal Year:
2023,
Volume and Issue:
19(8), P. 1202 - 1213
Published: May 12, 2023
Deprescribing
is
a
strategy
for
reducing
the
use
of
potentially
inappropriate
medications
older
adults.
Limited
evidence
exists
on
development
strategies
to
support
healthcare
professionals
(HCPs)
deprescribing
frail
adults
in
long-term
care
(LTC).
To
design
an
implementation
strategy,
informed
by
theory,
behavioural
science
and
consensus
from
HCPs,
which
facilitates
LTC.
This
study
was
consisted
3
phases.
First,
factors
influencing
LTC
were
mapped
behaviour
change
techniques
(BCTs)
using
Behaviour
Change
Wheel
two
published
BCT
taxonomies.
Second,
Delphi
survey
purposively
sampled
HCPs
(general
practitioners,
pharmacists,
nurses,
geriatricians
psychiatrists)
conducted
select
feasible
BCTs
deprescribing.
The
rounds.
Using
results
literature
used
effective
interventions,
could
form
shortlisted
research
team
based
acceptability,
practicability
effectiveness.
Finally,
roundtable
discussion
held
with
purposeful,
convenience
sample
general
pharmacists
nurses
prioritise
tailor
proposed
Factors
34
BCTs.
completed
16
participants.
Participants
reached
that
26
feasible.
Following
assessment,
21
included
roundtable.
identified
lack
resources
as
primary
barrier
address.
agreed
incorporated
11
education-enhanced
3-monthly
multidisciplinary
review,
led
nurse,
at
site.
incorporates
HCPs'
experiential
understanding
nuances
thus
addresses
systemic
barriers
this
context.
designed
five
determinants
best
engaging
Orvosi Hetilap,
Journal Year:
2023,
Volume and Issue:
164(24), P. 931 - 941
Published: June 18, 2023
A
gyógyszerrosta
(az
angol
deprescribing
magyar
megfelelője)
tervezett,
szisztematikus
gyógyszerleépítési
folyamat,
amely
egészségügyi
szakember
felügyeletével
zajlik,
és
lényegében
a
helyes
gyógyszerrendelési
gyakorlat
részének
tekintendő.
nemcsak
teljes
gyógyszerelhagyást
jelentheti,
hanem
dóziscsökkentés
folyamata
is
lehet.
Megtervezése
során
létfontosságú
figyelembe
venni
terápiás
célkitűzéseket,
valamint
beteg
egészségi
állapotát,
időbeli
életkilátását,
értékrendjét
igényeit.
célja
betegenként
változhat,
alapvetően
azonban
prioritásnak
tekinthető
számára
fontos
célok
elérése,
életminőségének
javítása.
Közleményünkben
nemzetközi
szakirodalom
alapján
áttekintjük
folyamatának
lehetséges
célpontjait:
azokat
nagy
kockázatú
betegcsoportokat,
amelyeknél
előnyös
lehet
gyógyszerleépítés;
gyógyszereket
gyógyszercsoportokat,
amelyek
szedése
esetén
szükség
terápia
felülvizsgálatára;
összefoglaljuk
folyamat
színtereit.
Ezenkívül
kitérünk
általános
lépéseire,
előnyeire,
kockázataira,
ismertetjük
rendelkezésre
álló
specifikus
irányelveket,
algoritmusokat.
Részletesen
tárgyaljuk
folyamatot
segítő
hátráltató
tényezőket,
mind
az
szakemberek,
pedig
betegek
szemszögéből,
végül
kezdeményezésekre
jövőjére
is.
Orv
Hetil.
2023;
164(24):
931–941.
BMC Health Services Research,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: July 26, 2024
Abstract
Background
Collaboration
between
physicians
and
pharmacists
facilitates
the
conduct
of
medication
optimisation
efforts.
In
context
deprescribing,
pharmacists’
roles
are
often
described
as
making
deprescribing
recommendations
to
physicians.
Little
is
known
about
factors
associated
with
willingness
make
their
interprofessional
collaboration
in
Swiss
primary
care
settings.
Objective
To
explore
pharmacists'
perspectives
on
older
adults,
preferences
for
Methods
this
cross-sectional
study,
a
random
sample
1000
pharmacist
members
Pharmacists
Association
pharmaSuisse
was
invited
participate
survey
optimisation,
collaboration.
The
contained
three
case
vignettes
multimorbid
patients
polypharmacy
aged
≥
80
years
old,
different
levels
dependency
activities
daily
living
(ADL)
cardiovascular
disease
(CVD).
For
each
vignette,
were
asked
if
which
medications
they
would
deprescribe.
We
calculated
proportions
deprescribe
by
vignette
performed
multilevel
logistic
regression
assess
associations
CVD,
ADL,
Results
One
hundred
thirty-eight
(14%)
responded
survey:
113
(82%)
female,
mean
age
44
(
SD
=
11),
66%
n
77)
reported
having
never
received
any
specific
training
how
structured
reviews.
Eighty-three
(72%)
be
confident
identifying
opportunities.
All
willing
1
all
vignettes.
Patients
CVD
at
lower
odds
deprescribed
(OR
0.27,
95%CI
0.21
0.36).
Willingness
higher
ADL
(medium
versus
low
dependency:
OR
0.68,
0.54
0.87,
high
0.72,
0.56
0.91).
However,
effect
significantly
modified
history
CVD.
five
(97%)
interact
clarify
questions
regarding
prescriptions
least
once
week
88
(81%)
wished
more
involved
review.
Conclusion
suggestions
polypharmacy,
but
two-thirds
no
formal
perform
like
process
review
should
leveraged
Drugs - Real World Outcomes,
Journal Year:
2022,
Volume and Issue:
10(1), P. 97 - 106
Published: Nov. 27, 2022
Deprescribing
is
associated
with
positive
health
outcomes
for
older
adults
in
long-term
care
(LTC),
however
deprescribing
not
universally
implemented.
The
primary
aim
of
this
study
was
to
estimate
the
prevalence
potentially
inappropriate
medications
(PIMs)
prescribed
frail
Irish
facilities
(LTCFs),
as
identified
by
Screening
Tool
Older
Persons
Prescriptions
Frail
limited
life
expectancy,
version
2
(STOPPFrail
v2).
A
retrospective
chart
review
conducted
two
publicly
funded
LTCFs
Ireland.
Eligible
participants
were
those
(1)
≥
65
years
age;
(2)
resident
a
LTCF;
(3)
eligible
per
STOPPFrail
v2
criteria
site's
Medical
Officer;
and
(4)
receiving
regular
medication.
Data
collected
included
age,
sex,
drug,
dose,
frequency,
regular/pro
re
nata
prescribing
indication/relevant
diagnoses.
Rates
polypharmacy
(taking
five
or
more
medications)
excessive
10
calculated.
used
identify
PIMs;
however,
clinical
measurements
taken.
Descriptive
association
statistics
Of
103
residents,
89
age
categorised
therefore
inclusion
study.
eligible,
85
(95.5%)
had
57
(64%)
experienced
polypharmacy.
mean
number
10.8
(±
3.8),
total
17.7
5)
diagnoses
5.5
2.5).
PIMs
4.8
2.6).
participants,
59.6%
at
least
one
medicine
without
documented
indication,
while
61.8%,
42.7%
30.3%
PIM
from
vitamin
D,
antihypertensives
proton
pump
inhibitors
drug
classes,
respectively.
Medication
use
high
among
LTC
concern.
Lack
clear
indication
appears
be
an
issue
LTC,
affecting
healthcare
professionals'
engagement
deprescribing.
may
overestimated
antihypertensives/antidiabetic
classes
due
lack
measurements.