
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Language: Английский
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Language: Английский
JAC-Antimicrobial Resistance, Journal Year: 2024, Volume and Issue: 6(2)
Published: March 5, 2024
Antimicrobial resistance (AMR) is a global public health crisis. This study assessed the general public's consumption of antibiotics and associated factors in Lusaka district Zambia.
Language: Английский
Citations
14JAC-Antimicrobial Resistance, Journal Year: 2024, Volume and Issue: 6(3)
Published: May 6, 2024
Antimicrobial resistance (AMR) poses a threat to public health globally. Despite its consequences, there is little information about the knowledge, awareness, and practices towards AMR among healthcare workers (HCWs). Therefore, this study assessed awareness regarding antimicrobial use (AMU), stewardship (AMS) HCWs who are involved in implementation of AMS activities across eight hospitals Zambia.
Language: Английский
Citations
13JAC-Antimicrobial Resistance, Journal Year: 2024, Volume and Issue: 6(2)
Published: March 5, 2024
Abstract Background The overuse and misuse of antimicrobials has worsened the problem antimicrobial resistance (AMR) globally. This study investigated AMR profiles Escherichia coli isolated from clinical environmental samples in Lusaka, Zambia. Methods was a cross-sectional conducted February 2023 to June using 450 samples. VITEK® 2 Compact used identify E. perform susceptibility testing. Data analysis done WHONET 2022 SPSS version 25.0. Results Of samples, 66.7% (n = 300) were whereas 33.3% 150) Overall, 47.8% 215) (37.8% 10% environmental) tested positive for coli. 215 isolates, 66.5% MDR 42.8% ESBL-producers. Most isolates resistant ampicillin (81.4%), sulfamethoxazole/trimethoprim (70.7%), ciprofloxacin (67.9%), levofloxacin (64.6%), ceftriaxone (62.3%) cefuroxime (62%). Intriguingly, highly susceptible amikacin (100%), imipenem (99.5%), nitrofurantoin (89.3%), ceftolozane/tazobactam (82%) gentamicin (72.1%). Conclusions found high some antibiotics that are commonly humans. isolation ESBL-producing is public health concern requires urgent action. Therefore, there need instigate strengthen interventional strategies including stewardship programmes combat
Language: Английский
Citations
10Pharmacology & Pharmacy, Journal Year: 2024, Volume and Issue: 15(12), P. 403 - 465
Published: Jan. 1, 2024
Language: Английский
Citations
6Antimicrobial Stewardship & Healthcare Epidemiology, Journal Year: 2024, Volume and Issue: 4(1)
Published: Jan. 1, 2024
Antimicrobial stewardship programs are very essential in addressing the problem of drug-resistant infections. The WHO Access, Watch, and Reserve (AWaRe) classification antibiotics is monitoring rational use antibiotics. Therefore, this study evaluated awareness AWaRe among pharmacy professionals Zambia.
Language: Английский
Citations
4Systematic Reviews, Journal Year: 2025, Volume and Issue: 14(1)
Published: Feb. 26, 2025
Antibiotic self-medication (ASM) is when a person takes antibiotics without prescription or consulting healthcare professional. These practices contribute to the misuse of medicines and antibiotic resistance which growing global health threat that can lead longer hospital stays, higher costs, increased mortality rates. Though various studies have been conducted on ASM in different countries, there has not yet systematic review comprehensively assesses problem entire globe. Hence, this meta-analysis aimed evaluate pooled prevalence reasons for its practice. A search electronic registers databases was PubMed, Medline, Embase, Scopus, Web Science, Google Scholar, gray literature including institutional repositories, national databases. It used carefully selected keywords indexing terms past ten years. The Joanna Briggs Institute's critical checklist extracted relevant data after appraisal. Narrative analysis descriptive while Comprehensive Meta-Analysis (CMA) Software analyze quantitative data. Statistics were look heterogeneity, publication bias, correlations. Sensitivity tests sub-group employed compare outcomes. p-value < 0.05 considered significant all cases. Seventy-one included meta-analysis. total number participants 63,251 with sample sizes ranging from 110 15,526. In primary outcomes, ranged 0.65 92.2%. globally 43.0% (95% CI: 38.0, 48.1%). high degree heterogeneity across shown I2 = 99.2%, p 0.001 assuming random effect model. subgroup analysis, highest 55.2% 47.2, 63.2) sub-Saharan Africa followed by Middle East, North Africa, Greater Arabia at 48.3% 38.3, 58.4), Europe 34.7% CI:18.0, 56.4), Asia 25.8% 18.6, 34.6). Students identified as major users 62.1% 53.7, 69.7). meta-regression showed coefficient 0.0365, -0.0117, -0.0001 year publication, recall time, size, respectively. Publication bias demonstrated asymmetrical distribution funnel plot, Eggers regression greater than (0.264). Moreover, knowledge (46.19% 27.99, 65.46)), previous successful experiences (39.13% 30.13, 48.93)), perceiving illness minor (38.10% 27.19, 50.37)) top three proportion practicing ASM. practice among African student users. experience most frequent reason reported. Educational level, gender, age often mentioned predictor factors. designing interventional approaches consider burdens target population tackle might benefit averting antimicrobial resistance.
Language: Английский
Citations
0Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown
Published: March 11, 2025
Language: Английский
Citations
0Creative Education, Journal Year: 2025, Volume and Issue: 16(03), P. 401 - 416
Published: Jan. 1, 2025
Language: Английский
Citations
0JAC-Antimicrobial Resistance, Journal Year: 2024, Volume and Issue: 6(4)
Published: July 3, 2024
Antimicrobial resistance (AMR) is a global public health problem affecting healthcare systems. Short-term antibiotic non-adherence thought to be one of the factors contributing resistance. This study aimed evaluate knowledge and practices towards short-term use on self-reported adherence among patients visiting level-1 hospitals in Lusaka, Zambia.
Language: Английский
Citations
3Health Science Reports, Journal Year: 2024, Volume and Issue: 7(9)
Published: Aug. 30, 2024
Antibiotic misuse represent a significant global health challenge, with medical students positioned as key figures in promoting responsible antibiotic usage. This study investigates the knowledge, attitudes, and practices (KAP) regarding use among Bangladesh, aiming to identify areas for targeted educational policy interventions.
Language: Английский
Citations
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