The Science of The Total Environment,
Journal Year:
2023,
Volume and Issue:
886, P. 163991 - 163991
Published: May 9, 2023
Endocrine
disrupting
chemicals
(EDCs)
can
interfere
with
hormonal
actions
and
have
been
associated
a
higher
incidence
of
metabolic
disorders.
They
affect
numerous
physiological,
biochemical,
endocrinal
activities,
including
reproduction,
metabolism,
immunity,
behavior.
The
purpose
this
review
was
to
elucidate
the
association
EDCs
in
food
gut
microbiota
EDC
exposure
induces
changes
that
lead
microbial
dysbiosis.
Products
by-products
released
by
metabolism
be
taken
up
host.
Changes
composition
production
metabolites
may
major
impact
on
host
metabolism.
Trends in Ecology & Evolution,
Journal Year:
2022,
Volume and Issue:
38(1), P. 35 - 43
Published: Oct. 13, 2022
Non-target
organisms
are
globally
exposed
to
herbicides.
While
many
herbicides
-
for
example,
glyphosate
were
initially
considered
safe,
increasing
evidence
demonstrates
that
they
have
profound
effects
on
ecosystem
functions
via
altered
microbial
communities.
We
provide
a
comprehensive
framework
how
herbicide
residues
may
modulate
ecosystem-level
outcomes
alteration
of
microbiomes.
The
changes
in
soil
microbiome
likely
influence
key
nutrient
cycling
and
plant-soil
processes.
Herbicide-altered
affects
plant
animal
performance
can
trophic
interactions
such
as
herbivory
pollination.
These
expected
lead
even
evolutionary
consequences
both
microbes
hosts.
Tackling
the
threats
caused
by
agrochemicals
services
requires
tools
solutions
based
understanding
microbe-mediated
risks.
Environment International,
Journal Year:
2024,
Volume and Issue:
186, P. 108569 - 108569
Published: March 20, 2024
Environmental
toxicants
(ETs)
are
associated
with
adverse
health
outcomes.
Here
we
hypothesized
that
exposures
to
ETs
linked
obesity
and
insulin
resistance
partly
through
a
dysbiotic
gut
microbiota
changes
in
the
serum
levels
of
secondary
bile
acids
(BAs).
Serum
BAs,
per-
polyfluoroalkyl
substances
(PFAS)
additional
twenty-seven
were
measured
by
mass
spectrometry
264
Danes
(121
men
143
women,
aged
56.6
±
7.3
years,
BMI
29.7
6.0
kg/m
Environmental Pollution,
Journal Year:
2024,
Volume and Issue:
348, P. 123732 - 123732
Published: March 8, 2024
The
gut-brain
axis
is
a
crucial
interface
between
the
central
nervous
system
and
gut
microbiota.
Recent
evidence
shows
that
exposure
to
environmental
contaminants,
such
as
heavy
metals,
can
cause
dysbiosis
in
microbiota,
which
may
affect
communication,
impacting
aspects
of
brain
function
behavior.
This
systematic
review
literature
aims
evaluate
whether
deleterious
effects
on
due
metal
could
be
mediated
by
changes
microbiota
profile.
Animal
studies
involving
metals
comparison
with
control
group
evaluated
neuropsychological
outcomes
and/or
molecular
along
analysis
composition
were
reviewed.
authors
independently
assessed
for
inclusion,
extracted
data
risk
bias
using
protocol
Systematic
Review
Center
Laboratory
Experimentation
(SYRCLE)
preclinical
studies.
A
search
3
databases
yielded
16
eligible
focused
lead
(n
=
10),
cadmium
1),
mercury
3),
manganese
combined
Pb
Mn
1).
animal
species
rats
7),
mice
4),
zebrafish
carp
1)
fruit
fly
Heavy
found
adversely
cognitive
function,
behavior,
neuronal
morphology.
Moreover,
was
associated
abundance
specific
bacterial
phyla,
Firmicutes
Proteobacteria,
play
roles
health.
In
some
studies,
these
alterations
correlated
learning
memory
impairments
mood
disorders.
interplay
suggests
induce
direct
indirect
through
contributing
neurotoxicity
development
However,
small
number
papers
under
makes
it
difficult
draw
definitive
conclusions.
Further
research
warranted
unravel
underlying
mechanisms
translational
implications
human
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(5), P. 708 - 708
Published: April 29, 2021
It
is
generally
accepted
that
gut
microbiota,
inflammation
and
obesity
are
linked
to
the
development
of
cardiovascular
diseases
other
chronic/non-communicable
pathological
conditions,
including
cancer,
neurodegenerative
ageing-related
disorders.
In
this
scenario,
oxidative
stress
plays
a
pivotal
role.
Evidence
suggests
global
dietary
patterns
may
represent
tool
in
counteracting
stress,
thus
preventing
onset
related
stress.
More
specifically,
based
on
regular
consumption
fruits
vegetables
(i.e.,
Mediterranean
diet)
have
been
licensed
by
various
national
nutritional
guidelines
many
countries
for
their
health-promoting
effects.
Such
patterns,
indeed,
result
being
rich
specific
components,
such
as
fiber,
minerals,
vitamins
antioxidants,
whose
beneficial
effects
human
health
widely
reported.
This
potential
nutraceutical
power
components.
manuscript,
we
summarize
most
relevant
evidence
reporting
impact
antioxidants
microbiota
composition,
obesity,
underline
implicated
complex
interplay
between
suggesting
possible
role
modulation
chronic
maintenance
wellness.
Do
all
roads
lead
Rome?
