Environmental Science & Technology,
Journal Year:
2022,
Volume and Issue:
56(10), P. 6560 - 6573
Published: May 10, 2022
Prenatal
chemical
exposures
can
influence
maternal
and
child
health;
however,
few
industrial
chemicals
are
routinely
biomonitored.
We
assessed
an
extensive
panel
of
contemporary
emerging
in
171
pregnant
women
across
the
United
States
(U.S.)
Puerto
Rico
Environmental
influences
on
Child
Health
Outcomes
(ECHO)
Program.
simultaneously
measured
urinary
concentrations
89
analytes
(103
total
representing
73
parent
compounds)
nine
groups:
bactericides,
benzophenones,
bisphenols,
fungicides
herbicides,
insecticides,
organophosphate
esters
(OPEs),
parabens,
phthalates/alternative
plasticizers,
polycyclic
aromatic
hydrocarbons
(PAHs).
estimated
associations
creatinine-adjusted
with
sociodemographic
specimen
characteristics.
Among
our
diverse
prenatal
population
(60%
non-Hispanic
Black
or
Hispanic),
we
detected
≥1
participant
36
>50%
participants.
Five
not
currently
included
U.S.
biomonitoring
were
≥90%
samples:
benzophenone-1,
thiamethoxam,
mono-2-(propyl-6-carboxy-hexyl)
phthalate,
monocarboxy
isooctyl
monohydroxy-iso-decyl
phthalate.
Many
analyte
higher
among
Hispanic
ethnicity
compared
to
those
White
women.
Concentrations
certain
decreased
calendar
year,
whereas
their
replacements
increased.
Our
largest
study
date
identified
widespread
prevalent
understudied
a
sample
Nutrients,
Journal Year:
2019,
Volume and Issue:
11(9), P. 2136 - 2136
Published: Sept. 6, 2019
Bisphenol
A
(BPA)
is
the
most
well-known
compound
from
bisphenol
family.
As
BPA
has
recently
come
under
pressure,
it
being
replaced
by
compounds
very
similar
in
structure,
but
data
on
occurrence
of
these
analogues
food
and
human
matrices
are
limited.
The
main
objective
this
work
was
to
investigate
exposure
associated
health
effects.
We
performed
a
literature
review
available
research
made
humans,
vivo
vitro
tests.
findings
support
idea
that
may
have
an
impact
health,
especially
terms
obesity
other
adverse
effects
children.
Environmental Science & Technology,
Journal Year:
2021,
Volume and Issue:
55(3), P. 1953 - 1963
Published: Jan. 26, 2021
Bisphenol
A
(BPA)
analogues,
used
in
a
range
of
products
due
to
health
concerns
regarding
BPA,
have
emerged
as
ubiquitous
environmental
contaminants
worldwide.
This
study
aims
evaluate
the
levels
nine
bisphenols
(BPs)
and
eight
biomarkers
(malondialdehyde,
MDA;
8-hydroxy-2′-deoxyguanosine,
8-OHdG;
estradiol,
E2;
follicle-stimulating
hormone,
FSH;
luteinizing
LH;
complement
compound
3,
C3;
immunoglobulin
M,
IgM
c-reaction
protein,
CRP)
human
serum
(n
=
353)
explore
their
potential
relationships.
The
detection
rates
(DRs)
BPs
samples
taken
from
people
working
dense
industrial
area
Shenzhen
(Guangdong
Province,
China)
were
over
72%
except
for
bisphenol
B
(BPB)
(DR
27.5%).
mean
concentrations
P
(BPP),
BPB,
F
(BPF),
FL
(BPFL),
4,4′-dihydroxy-benzophenone
(DHBP),
AF
(BPAF),
4,4′-thiodiphenol
(TDP)
S
(BPS)
42.062,
2.083,
0.765,
0.578,
0.423,
0.402,
0.191,
0.120,
0.071
ng/mL,
respectively.
BPA
BPFL
significantly
correlated
with
level
oxidative
stress
indices
MDA
BPAF,
DHBP
strongly
endocrine
disturbance
E2,
FSH,
BPF,
DHBP,
BPAF
apparently
related
immune
interference
C3
IgM.
also
suggests
multiple
impacts
(oxidative
stress,
disturbance,
interference)
mediated
by
vivo.
To
our
knowledge,
this
is
first
report
correlations
among
these
system
collected
areas.
Antioxidants,
Journal Year:
2022,
Volume and Issue:
11(3), P. 477 - 477
Published: Feb. 28, 2022
Oxidative
stress
(OS)
due
to
an
imbalance
between
reactive
oxygen
species
(ROS)
and
antioxidants
has
been
established
as
important
factor
that
can
negatively
affect
the
outcomes
of
assisted
reproductive
techniques
(ARTs).
Excess
ROS
exert
their
pathological
effects
through
damage
cellular
lipids,
organelles,
DNA,
alteration
enzymatic
function,
apoptosis.
be
produced
intracellularly,
from
immature
sperm,
oocytes,
embryos.
Additionally,
several
external
factors
may
induce
high
production
in
ART
setup,
including
atmospheric
oxygen,
CO2
incubators,
consumables,
visible
light,
temperature,
humidity,
volatile
organic
compounds,
culture
media
additives.
Pathological
amounts
also
generated
during
cryopreservation-thawing
process
gametes
or
Generally,
these
act
at
any
stage
ART,
gamete
preparation
embryo
development,
till
blastocyst
stage.
In
this
review,
we
discuss
vitro
conditions
environmental
responsible
for
induction
OS
setting.
addition,
describe
on
Furthermore,
highlight
strategies
ameliorate
impact
whole
human
period,
Environmental Science & Technology,
Journal Year:
2022,
Volume and Issue:
56(10), P. 6560 - 6573
Published: May 10, 2022
Prenatal
chemical
exposures
can
influence
maternal
and
child
health;
however,
few
industrial
chemicals
are
routinely
biomonitored.
We
assessed
an
extensive
panel
of
contemporary
emerging
in
171
pregnant
women
across
the
United
States
(U.S.)
Puerto
Rico
Environmental
influences
on
Child
Health
Outcomes
(ECHO)
Program.
simultaneously
measured
urinary
concentrations
89
analytes
(103
total
representing
73
parent
compounds)
nine
groups:
bactericides,
benzophenones,
bisphenols,
fungicides
herbicides,
insecticides,
organophosphate
esters
(OPEs),
parabens,
phthalates/alternative
plasticizers,
polycyclic
aromatic
hydrocarbons
(PAHs).
estimated
associations
creatinine-adjusted
with
sociodemographic
specimen
characteristics.
Among
our
diverse
prenatal
population
(60%
non-Hispanic
Black
or
Hispanic),
we
detected
≥1
participant
36
>50%
participants.
Five
not
currently
included
U.S.
biomonitoring
were
≥90%
samples:
benzophenone-1,
thiamethoxam,
mono-2-(propyl-6-carboxy-hexyl)
phthalate,
monocarboxy
isooctyl
monohydroxy-iso-decyl
phthalate.
Many
analyte
higher
among
Hispanic
ethnicity
compared
to
those
White
women.
Concentrations
certain
decreased
calendar
year,
whereas
their
replacements
increased.
Our
largest
study
date
identified
widespread
prevalent
understudied
a
sample
