SARS-CoV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis

American Journal of Obstetrics and Gynecology, Journal Year: 2021, Volume and Issue: 226(1), P. 68 - 89.e3

Published: July 21, 2021

To examine the relationship between SARS-CoV-2 infection during pregnancy and risk for preeclampsia.

Language: Английский

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Risk Factors of Severe COVID-19: A Review of Host, Viral and Environmental Factors

Viruses, Journal Year: 2023, Volume and Issue: 15(1), P. 175 - 175

Published: Jan. 7, 2023

The clinical course and outcome of COVID-19 are highly variable, ranging from asymptomatic infections to severe disease death. Understanding the risk factors is relevant both in setting at epidemiological level. Here, we provide an overview host, viral environmental that have been shown or (in some cases) hypothesized be associated with outcomes. considered detail include age frailty, genetic polymorphisms, biological sex (and pregnancy), co- superinfections, non-communicable comorbidities, immunological history, microbiota, lifestyle patient; variation infecting dose; socioeconomic factors; air pollution. For each category, compile (sometimes conflicting) evidence for association factor outcomes (including strength effect) outline possible action mechanisms. We also discuss complex interactions between various factors.

Language: Английский

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Family integration and skin-to-skin contact with the newborn favors the recovery of the hospitalized patient: experiences of its implementation in an Obstetric Critical Care Unit

Deleted Journal, Journal Year: 2023, Volume and Issue: 2, P. 33 - 33

Published: Nov. 30, 2023

Introduction: skin-to-skin contact (COPAP) on the maternal thorax allows preterm newborn to experience tactile, auditory, and proprioceptive stimuli, heart rate, sound of flow great vessels caresses while being held; this stimulates self-regulation necessary for survival these infants.Aim: describe experiences in implementation a protocol family integration with order favor recovery patient hospitalized.Methods: non-experimental, analytical study was carried out health systems services. The alternatively used secondary source data from technical documentation sector statistical records service. Results: regarding characteristics puerperal women who participated protocol, those aged between 25 30 years predominated, an interperiod growth 21,9 %. most frequent pathologies were Severe Eclampsia Pre-Eclampsia; only 4 found negative growth. Finally, according distribution RN admission mother's hospitalization day, we hospitalizations longer than days, decrease that 3 indicator remained general growth.Conclusions: It can be affirmed is recommended, beneficial, safe practice. availability agreed upon by services involved makes it possible apply as routine care procedure

Language: Английский

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Counseling in maternal–fetal medicine: SARS‐CoV‐2 infection in pregnancy

Ultrasound in Obstetrics and Gynecology, Journal Year: 2021, Volume and Issue: 57(5), P. 687 - 697

Published: March 16, 2021

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a zoonotic that crossed species to infect humans, causing disease 2019 (COVID‐19). Despite potentially higher risk of pregnant women acquiring SARS‐CoV‐2 infection compared with the non‐pregnant population (particularly in some ethnic minorities), no additional specific recommendations avoid exposure are needed pregnancy. The most common clinical symptoms and laboratory signs pregnancy fever, cough, lymphopenia elevated C‐reactive protein levels. Pregnancy associated severe population, including pneumonia, admission intensive care unit death, even after adjusting for potential factors outcomes. miscarriage does not appear be increased infection. Evidence regards preterm birth perinatal mortality conflicting, but these risks generally only symptomatic, hospitalized women. vertical transmission, defined as transmission from mother fetus or newborn, low. Fetal invasive procedures considered safe infection, although evidence still limited. In COVID‐19, use steroids should avoided if clinically indicated; preferred regimen 2‐day course dexamethasone followed by an 8‐day methylprednisolone. Non‐steroidal anti‐inflammatory drugs may used there contraindications. Hospitalized COVID‐19 undergo thromboprophylaxis throughout duration hospitalization at least until discharge, preferably low molecular weight heparin. who have recovered period serious critical illness offered fetal growth scan about 14 days recovery their illness. asymptomatic mildly symptomatic tested positive full term (i.e. ≥ 39 weeks gestation), induction labor might reasonable. To date, clear consensus on optimal timing delivery critically ill few symptoms, management follow routine evidence‐based guidelines. Regardless status, mothers infants remain together breastfeeding, skin‐to‐skin contact, kangaroo rooming‐in day night practiced, while applying necessary prevention control measures. Many already undergone vaccination, mostly USA where first reports show significant difference outcomes receiving vaccination during background risk. Vaccine‐generated antibodies were present umbilical cord blood breast milk samples lactating received mRNA vaccine. Based available limited data safety vaccine pregnancy, it seems reasonable offer option accurate counseling unknown © 2021 International Society Ultrasound Obstetrics Gynecology.

Language: Английский

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Adverse perinatal outcomes in a large United States birth cohort during the COVID-19 pandemic

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2022, Volume and Issue: 4(3), P. 100577 - 100577

Published: Feb. 1, 2022

Language: Английский

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Obstetric and perinatal outcomes of pregnancies with COVID 19: a systematic review and meta-analysis

The Journal of Maternal-Fetal & Neonatal Medicine, Journal Year: 2022, Volume and Issue: 35(25), P. 9742 - 9758

Published: March 13, 2022

Objective This meta-analysis aimed at comparing obstetric and perinatal outcomes in laboratory-tested pregnant women for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection before delivering.Method We performed a comprehensive systematic review of electronic databases studies reporting with without SARS-CoV-2 infection, as determined by polymerase chain reaction (PCR) delivery, during the pandemic period published up to June 25, 2021. Results are reported mean difference (MD) or odds ratio (OR) their 95% confidence interval (CI).Results Seventeen observational low moderate risk bias, on 2,769 positive PCR test 13,807 negative test. Pregnant delivered an earlier gestational age (MD −0.19; CI −0.36 −0.02 weeks), smoked less (OR 0.75; 0.61–0.94) were associated higher preeclampsia 1.30; 1.09–1.54), NICU admissions 2.37; 1.18–4.76), stillbirths 2.70; CI, 1.38–5.29), mortality 3.23; 1.23–8.52). There no significant differences between tested terms nulliparity, multiple pregnancies, diabetes, route labor induction, preterm birth, infant birth weight, 5 min Apgar scores < 7, small-for-gestational-age infants fetal malformations. Eleven included neonatal testing which was 129 infants, 20 positive.Conclusion Positive had preeclampsia/hypertensive disorders pregnancy, admissions, mortality.

Language: Английский

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SARS-CoV-2 Placentitis and Intraparenchymal Thrombohematomas Among COVID-19 Infections in Pregnancy

JAMA Network Open, Journal Year: 2022, Volume and Issue: 5(3), P. e225345 - e225345

Published: March 21, 2022

a Includes 1 placenta from dichorionic-diamniotic twins.b This category includes cases with severe complications such as respiratory distress requiring intubation, early neonatal death, or intraventricular hemorrhage.c may include of prematurity not previously specified severe.d Mild symptoms cough, fever, myalgias, chills, loss taste and smell, nausea vomiting, diarrhea.Severe pneumonia intensive care unit admission and/or intubation.e There be multiple indications for each delivery.

Language: Английский

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Effect of COVID-19 on antenatal care: experiences of medical professionals in the Netherlands

Reproductive Health, Journal Year: 2023, Volume and Issue: 20(1)

Published: March 8, 2023

COVID-19 has greatly affected the delivery of all health care services globally. Antenatal is one area that been impacted, despite fact attending antenatal check-ups essential for pregnant women and cannot be postponed. Little known about how exactly ANC provision changed in Netherlands, or changes have impacted midwives gynaecologists providing those services.This study used a qualitative research design to investigate individual national practice following onset pandemic. The involved document analysis protocols guidelines evaluate pandemic semi-structured interviews with providers (i.e., midwives).Guidance was issued by multiple organizations, during pandemic, on approach risk infection women, recommending several protect both providers. Both reported their practice. With less face-to-face consultations happening, digital technologies became critical women. Shorter fewer visits were reported, midwifery practices adjusting further than hospitals. Challenges, high workloads lack personal protective equipment discussed.The had an immense impact system. This negative positive effects Netherlands. It important learn from current adapt ANC, as well systems whole, better prepared future crises ensure continuous good quality care.COVID-19 healthcare global scale. Netherlands period. Our project focuses examining existing protocols, impacts providers, such gynaecologists. knowledge can beneficial adapting times emergencies, more resilient. uses involves 20 working which took part interviews, 9 analysed. indicates at different levels Many show service, should not cut back, but it implemented, emergency.

Language: Английский

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Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2

American Journal Of Pathology, Journal Year: 2021, Volume and Issue: 191(9), P. 1610 - 1623

Published: June 8, 2021

Language: Английский

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Management of pregnant women with COVID‐19: A tertiary pandemic center experience on 1416 cases

Journal of Medical Virology, Journal Year: 2021, Volume and Issue: 94(3), P. 1074 - 1084

Published: Oct. 29, 2021

The aim of this study is to share the comprehensive experience a tertiary pandemic center on pregnant women with COVID-19 and compare clinical outcomes between pregnancy trimesters. present prospective cohort consisted who were followed up at Ankara City Hospital March 11, 2020 February 20, 2021. Clinical characteristics perinatal compared A total 1416 (1400 singletons 16 twins) evaluated. Twenty-six (1.8%) patients admitted intensive care unit (ICU) maternal mortality was observed in six (0.4%) cases. Pregnancy complications 227 (16.1%) cases preterm labor most common one (n = 42, 2.9%). There 311, 433, 672 first, second, third trimesters pregnancy, respectively. Rates mild severe/critic highest first second trimesters, hospitalization rate trimester. complications, mortality, NICU admission rates similar groups. course disease obstetric may be different among worse even without any coexisting health problems.

Language: Английский

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