The impact of self-isolation on psychological wellbeing and how to reduce it: a systematic review

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 16, 2023

Abstract Self-isolation is a public health measure used to prevent the spread of infection, and which can have an impact on psychological wellbeing those going through it. It likely that self-isolation will be contain future outbreaks infectious disease. We synthesised evidence home general during COVID-19 pandemic. This systematic review was registered PROSPERO (CRD42022378140). searched Medline, PsycINFO, Web Science, Embase, grey literature (01 January 2020 13 December 2022). Our definition included adverse mental outcomes adaptive wellbeing. Studies investigated isolation in managed facilities, children, healthcare workers were excluded. followed PRISMA synthesis without meta-analysis (SWiM) guidelines. extracted data wellbeing, factors associated with interventions targeting self-isolation. 36 studies (most cross sectional, two longitudinal cohort studies, three assessed interventions, five qualitative). The mode quality rating ‘high-risk’. Depressive anxiety symptoms most investigated. Evidence for often inconsistent quantitative although qualitative consistently reported negative However, people pre-existing physical needs increased ill modifiable stressors been previous disease contexts, such as inadequate support, poor coping strategies, conflicting information, importance regular contact from trusted professionals. rare evaluative these had high or very risk bias. When implementing directives, officials should prioritise support more vulnerable individuals who needs, lack are facing significant life stressors. Clinicians play key role identifying supporting at risk. Focus directed toward address loneliness, worries, misinformation, whilst monitoring need additional support.

Language: Английский

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Intensified screening for SARS-CoV-2 in 18 emergency departments in the Paris metropolitan area, France (DEPIST-COVID): A cluster-randomized, two-period, crossover trial

PLoS Medicine, Journal Year: 2023, Volume and Issue: 20(12), P. e1004317 - e1004317

Published: Dec. 7, 2023

Background Asymptomatic and paucisymptomatic infections account for a substantial portion of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) transmissions. The value intensified screening strategies, especially in emergency departments (EDs), reaching asymptomatic patients helping to improve detection reduce transmission has not been documented. objective this study was evaluate EDs whether an SARS-CoV-2 strategy combining nurse-driven asymptomatic/paucisymptomatic with routine practice (intervention) could contribute higher compared alone, including symptomatic or hospitalized (control). Methods findings We conducted cluster-randomized, two-period, crossover trial from February 2021 May 18 the Paris metropolitan area, France. All adults visiting were eligible. At start first period, randomized intervention control by balanced block randomization stratification, alternative condition being applied second period. During included patients. addition practice, questionnaire about risk exposure symptoms test offered nurses all remaining primary outcome proportion newly diagnosed SARS-CoV-2–positive among EDs. Primary analysis intention-to-treat. analyzed using generalized linear mixed model (Poisson distribution) center period as random effects (intervention versus control) (modeled weekly categorical variable) fixed additional adjustment community incidence. periods, 69,248 69,104 patients, respectively, total 138,352 Patients had median age 45.0 years [31.0, 63.0], women represented 45.7% 6,332 completed questionnaire; 4,283 screened nurses, leading 224 new diagnoses. A 1,859 2,084 during respectively (adjusted analysis: 26.7/1,000 26.2/1,000, adjusted relative risk: 1.02 (95% confidence interval (CI) [0.94, 1.11]; p = 0.634)). main limitation is that it rapidly evolving epidemiological context. Conclusions results showed unlikely identify Trial registration number: ClinicalTrials.gov NCT04756609 .

Language: Английский

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Measuring and increasing rates of self-isolation in the context of infectious diseases: A systematic review with narrative synthesis

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 29, 2023

Abstract Background Self-isolation was used to prevent the spread of COVID-19 and will likely be in future infectious disease outbreaks. Method We conducted a systematic review following PRISMA SWiM guidelines. MEDLINE, PsycINFO, Embase, Web Science, PsyArXiv, medRxiv, grey literature sources were searched (1 January 2020 13 December 2022) using terms related COVID-19, isolation, adherence. Studies included if they contained original, quantitative data self-isolation adherence during pandemic. extracted definitions self-isolation, measures quantify adherence, rates, factors associated with The registered on PROSPERO (CRD42022377820). Findings 45 studies. inconsistently defined. Only four studies did not use self-report measure Of 41 measures, only one reported reliability; another gave indirect evidence for lack validity measure. Rates ranged from 0% 100%. There little that socio-demographic or psychological factors. Interpretation no consensus defining, operationalising, measuring self-isolation. study presented psychometric properties highlighting significant risk bias This, dearth scientifically rigorous evaluating effectiveness interventions increase is fundamental gap literature. Funding This funded by Research England Policy Support Fund 2022-23; authors supported NIHR Health Protection Unit Emergency Preparedness Response.

Language: Английский

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