Addiction,
Journal Year:
2021,
Volume and Issue:
117(6), P. 1510 - 1517
Published: Sept. 30, 2021
Abstract
Background
The
lack
of
an
agreed
international
minimum
approach
to
measuring
cannabis
use
hinders
the
integration
multidisciplinary
evidence
on
psychosocial,
neurocognitive,
clinical
and
public
health
consequences
use.
Methods
A
group
25
expert
researchers
convened
discuss
a
framework
for
standards
measure
globally
in
diverse
settings.
Results
expert‐based
consensus
upon
three‐layered
hierarchical
framework.
Each
layer—universal
measures,
detailed
self‐report
biological
measures—reflected
different
research
priorities
standards,
costs
ease
implementation.
Additional
work
is
needed
develop
valid
precise
assessments.
Conclusions
Consistent
proposed
across
research,
health,
practice
medical
settings
would
facilitate
harmonisation
consumption,
related
harms
approaches
their
mitigation.
Journal of Pain,
Journal Year:
2019,
Volume and Issue:
21(5-6), P. 722 - 730
Published: Nov. 9, 2019
Use
of
cannabis
to
alleviate
headache
and
migraine
is
relatively
common,
yet
research
on
its
effectiveness
remains
sparse.
We
sought
determine
whether
inhalation
decreases
ratings
as
well
gender,
type
(concentrate
vs
flower),
delta-9-tetrahydrocannabinol,
cannabidiol,
or
dose
contribute
changes
in
these
ratings.
Finally,
we
explored
evidence
for
tolerance
effects.
Archival
data
were
obtained
from
Strainprint,
a
medical
app
that
allows
patients
track
symptoms
before
after
using
different
strains
doses
cannabis.
Latent
change
score
models
multilevel
used
analyze
12,293
sessions
where
was
treat
7,441
migraine.
There
significant
reductions
use.
Men
reported
larger
than
women
use
concentrates
associated
with
flower.
Further,
there
PERSPECTIVE:
Inhaled
reduces
self-reported
severity
by
approximately
50%.
However,
appears
diminish
across
time
appear
time,
suggesting
effects
may
develop
continued
American Journal of Public Health,
Journal Year:
2019,
Volume and Issue:
109(9), P. 1294 - 1301
Published: July 18, 2019
Objectives.
To
assess
the
relationship
between
adult
cannabis
use
and
time-varying
local
measures
of
retail
market
presence
before
after
legalization
(2012)
opening
(2014)
in
Washington
State.Methods.
We
used
2009
to
2016
data
on
85
135
adults'
current
(any)
frequent
(20
or
more
days)
past-month
from
Behavioral
Risk
Factor
Surveillance
System
linked
retailer
proximity
density.
Multilevel
models
predicted
over
time,
accounting
for
nesting
within
communities.Results.
Current
grew
significantly
2016;
did
not
change
immediately
but
increased
subsequently
with
greater
access
retailers.
Specifically,
among
adults
living
areas
18
miles
a
and,
especially,
0.8
(odds
ratio
[OR]
=
1.45;
95%
confidence
interval
[CI]
1.24,
1.69).
Frequent
(OR
1.43;
CI
1.15,
1.77).
Results
related
geospatial
density
were
consistent.Conclusions.
Increasing
was
associated
use.Public
Health
Implications.
Policymakers
might
consider
limits
as
strategy
preventing
heavy
adults.
Scientific Reports,
Journal Year:
2021,
Volume and Issue:
11(1)
Published: April 26, 2021
Abstract
The
use
of
cannabidiol
(CBD)
in
electronic
cigarettes
is
widespread.
Previously,
it
was
reported
that
CBD
partly
transformed
to
THC
case
smoking
as
a
cigarette,
however,
the
pyrolysis
this
compound
has
not
been
assessed
extensively.
aim
our
study
investigate
effect
temperature
on
composition
products
CBD.
experiments
were
performed
typical
operating
range
e-cigarettes
(250–400
°C)
and
at
500
°C
under
both
inert
oxidative
conditions,
identified
quantified
by
GC–MS.
Depending
atmosphere,
25–52%
into
other
chemical
substances:
Δ
9
-THC,
8
cannabinol
cannabichromene
predominant
pyrolysates
all
formed
cyclization
reaction.
main
product
temperatures
conditions.
Our
results
point
out
can
be
considered
precursor
THC,
thus
bears
dangers
related
psychoactive
compound.
findings
are
fundamental
contributions
safety
profile
CBD-based
e-cigarettes.
Addiction,
Journal Year:
2021,
Volume and Issue:
117(6), P. 1510 - 1517
Published: Sept. 30, 2021
Abstract
Background
The
lack
of
an
agreed
international
minimum
approach
to
measuring
cannabis
use
hinders
the
integration
multidisciplinary
evidence
on
psychosocial,
neurocognitive,
clinical
and
public
health
consequences
use.
Methods
A
group
25
expert
researchers
convened
discuss
a
framework
for
standards
measure
globally
in
diverse
settings.
Results
expert‐based
consensus
upon
three‐layered
hierarchical
framework.
Each
layer—universal
measures,
detailed
self‐report
biological
measures—reflected
different
research
priorities
standards,
costs
ease
implementation.
Additional
work
is
needed
develop
valid
precise
assessments.
Conclusions
Consistent
proposed
across
research,
health,
practice
medical
settings
would
facilitate
harmonisation
consumption,
related
harms
approaches
their
mitigation.
