Measuring recent cannabis use across modes of delivery: Development and validation of the Cannabis Engagement Assessment DOI Creative Commons
Magdalen G. Schluter, David C. Hodgins

Addictive Behaviors Reports, Journal Year: 2022, Volume and Issue: 15, P. 100413 - 100413

Published: Feb. 8, 2022

Methods of cannabis engagement have proliferated in recent years, which many self-report measures do not adequately capture. There is a clear need for that capture current patterns use across range methods, and can be used to track changes over time. The study developed the Cannabis Engagement Assessment (CEA), measure past month dry flower, concentrate, edible products. A sample 349 participants from undergraduate student population broader community were recruited. To examine convergent validity CEA, completed engagement, misuse, use-related problems. assess divergent validity, also depression alcohol Criterion test–retest reliability examined subset 65 who re-completed CEA timeline follow-back interview (TLFB). Indicators frequency quantity showed good convergence with patterns, problematic Divergent was supported by lower associations problems symptoms. estimates TLFB. viable representative recreational engagement. Its focus on preceding 30 days lends itself measuring

Language: Английский

Association of cannabis potency with mental ill health and addiction: a systematic review DOI
Kat Petrilli,

Shelan Ofori,

Lindsey A. Hines

et al.

The Lancet Psychiatry, Journal Year: 2022, Volume and Issue: 9(9), P. 736 - 750

Published: July 25, 2022

Language: Английский

Citations

133
The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use DOI Creative Commons
Valentina Lorenzetti, Chandni Hindocha, Kat Petrilli

et al.

Addiction, Journal Year: 2021, Volume and Issue: 117(6), P. 1510 - 1517

Published: Sept. 30, 2021

Abstract Background The lack of an agreed international minimum approach to measuring cannabis use hinders the integration multidisciplinary evidence on psychosocial, neurocognitive, clinical and public health consequences use. Methods A group 25 expert researchers convened discuss a framework for standards measure globally in diverse settings. Results expert‐based consensus upon three‐layered hierarchical framework. Each layer—universal measures, detailed self‐report biological measures—reflected different research priorities standards, costs ease implementation. Additional work is needed develop valid precise assessments. Conclusions Consistent proposed across research, health, practice medical settings would facilitate harmonisation consumption, related harms approaches their mitigation.

Language: Английский

Citations

71
Prevalence and use of cannabis products and routes of administration among youth and young adults in Canada and the United States: A systematic review DOI
Elle Wadsworth, Sam Craft, Robert Calder

et al.

Addictive Behaviors, Journal Year: 2022, Volume and Issue: 129, P. 107258 - 107258

Published: Jan. 22, 2022

Language: Английский

Citations

54
Hours high as a proxy for marijuana use quantity in intensive longitudinal designs DOI Creative Commons
Brian H. Calhoun, Megan E. Patrick, Anne M. Fairlie

et al.

Drug and Alcohol Dependence, Journal Year: 2022, Volume and Issue: 240, P. 109628 - 109628

Published: Sept. 9, 2022

Language: Английский

Citations

26
Measuring white matter microstructure in 1,457 cannabis users and 1,441 controls: A systematic review of diffusion-weighted MRI studies DOI Creative Commons
Emily Robinson, John Gleeson, Arush Honnedevasthana Arun

et al.

Frontiers in Neuroimaging, Journal Year: 2023, Volume and Issue: 2

Published: March 7, 2023

Cannabis is the most widely used regulated substance by youth and adults. use has been associated with psychosocial problems, which have partly ascribed to neurobiological changes. Emerging evidence date from diffusion-MRI studies shows that cannabis users compared controls show poorer integrity of white matter fibre tracts, structurally connect distinct brain regions facilitate neural communication. However, recent thus far yet be integrated. Therefore, it unclear if differences in are evident consistently selected locations, specific metrics, whether these metrics exposure levels.We systematically reviewed results imaging between controls. We also examined associations other behavioral variables due changes matter. Our review was pre-registered PROSPERO (ID: 258250; https://www.crd.york.ac.uk/prospero/).We identified 30 including 1,457 1,441 aged 16-to-45 years. All but 6 reported group integrity. The consistent were lower fractional anisotropy within arcuate/superior longitudinal fasciculus (7 studies), corpus callosum (6 studies) as well higher mean diffusivity trace (4 studies). Differences onset especially (3 studies).The mechanisms underscoring unclear, they may include effects during youth, neurotoxic or neuro adaptations regular tetrahydrocannabinol (THC), exerts its binding receptors, a vulnerability predating use. Future multimodal neuroimaging studies, recently developed advanced can track over time define precision when region commence users, cessation recovers differences.www.crd.york.ac.uk/prospero/, identifier: 258250.

Language: Английский

Citations

14
High potency cannabis use, mental health symptoms and cannabis dependence: Triangulating the evidence DOI Creative Commons
Kat Petrilli, Lindsey A. Hines, Sally Adams

et al.

Addictive Behaviors, Journal Year: 2023, Volume and Issue: 144, P. 107740 - 107740

Published: April 24, 2023

Cannabis potency (concentration of Δ-9-Tetrahydrocannabinol) has been associated with risks adverse mental health outcomes and addiction but no studies have triangulated evidence from self-report objective measures cannabis potency. We hypothesised that users high would higher levels (a) anxiety, (b) depression (c) psychosis-like symptoms (d) dependence than lower cannabis.A cross-sectional study 410 participants donated a sample for analysis THC concentration reported their preference. These two exposure were investigated association dependence, depression, in separate linear/logistic regression models.High preference was slight increased risk after adjusting confounding, the exception use frequency (OR = 1.16, 95% CI 1.04-1.28). No found between dependence. There weak small anxiety. or symptoms.Users who preferred types might be at problematic use. This should considered caution as we not able to triangulate these results an measure More research is needed understand

Language: Английский

Citations

14
Epigenetic effects of cannabis: A systematic scoping review of behavioral and emotional symptoms associated with cannabis use and exocannabinoid exposure DOI Creative Commons
Ana Sofia Machado,

Miguel Bragança,

Maria Augusta Vieira‐Coelho

et al.

Drug and Alcohol Dependence, Journal Year: 2024, Volume and Issue: 263, P. 111401 - 111401

Published: July 27, 2024

Recent research suggests that epigenetic modifications may mediate the behavioral effects of cannabis, influencing exocannabinnoids' long term in cognitive function and its role emergence psychotic symptoms. In this systematic scoping review, we assessed current evidence associated with use cannabis or exocannabinoid administration their relationship emotional We searched PubMed, Cochrane CENTRAL, Web Science, up to January 2022, using terms "cannabis" "epigenetics." The search yielded 178 articles, which 43 underwent full article revision; 37 articles were included review. gathered observational cross-sectional studies conducted on human subjects experimental designs animal models conveyed disparity dosage, methods assessment targeted mechanisms. Nine performed epigenome-wide analysis identification differentially methylated sites; most these found a global hypomethylation, enrichment genes related cellular survival neurodevelopment. Other methylation at specific exposure was reduced Cg05575921, DNMT1, DRD2, COMT, DLGAP2, Arg1, STAT3, MGMT, PENK, while hypermethylation DNMT3a/b, NCAM1, AKT1. review an exocannabinoid-induced changes modulate depressive-anxious, psychotic, addictive behavioural phenotypes. Further will require dosage exposure/administration uniformization customized pool assess suitability as biomarkers for psychiatric diseases.

Language: Английский

Citations

5
Associations between hair-derived cannabinoid levels, self-reported use, and cannabis-related problems DOI Creative Commons
Emese Kroon, Janna Cousijn, Francesca M. Filbey

et al.

Psychopharmacology, Journal Year: 2024, Volume and Issue: 241(6), P. 1237 - 1244

Published: Feb. 26, 2024

As cannabis potency and use are increasing in newly legalized markets, it is increasingly important to measure examine the effects of cannabinoid exposure.

Language: Английский

Citations

4
Sleep Health, Self-Medication, and Cannabis Risk: A Bidirectional Model and Research Agenda DOI
Patricia A. Goodhines, Krutika Rathod, Leah Cingranelli

et al.

Current Sleep Medicine Reports, Journal Year: 2025, Volume and Issue: 11(1)

Published: Jan. 3, 2025

Language: Английский

Citations

0
Assessing the frequency, quantity, and heavy use patterns of marijuana flower among adults with HIV in Florida DOI Open Access
Donald D Porchia, Yancheng Li, Gladys E. Ibañez

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: March 15, 2025

Measuring the quantity of marijuana flower use is challenging and there no standardized method measurement, yet it critical for cannabis researchers investigating its effects on health outcomes. We sought to identify frequency used per day, average size a joint, blunt or bowl, amount consumed hit. also examine distribution heavy daily in terms grams day. As part Marijuana Associated Planning Long-term Effects (MAPLE) longitudinal cohort study, an underrepresented, population persons with HIV (PWH), who were users (n = 253) (60.1% Age ≥50, 54.4% Male, 66.4% Black) completed retrospective, calendar-based timeline follow-back (TLFB) measure. Participants reported their grams, number hits dose, methods consumption during 30 days prior each study visit. Of 253 participants, 208 (82%) exclusively 52% daily, median 0.8 grams/day. The most common blunts (33%, 1.0 grams), joints (32%, 0.5 bowls (12%, 0.3 grams). hit was 0.063 grams. proportion had at least one day month, every month 30% 6% when defined as 3 grams/day, 43% 13% 2 59% 23% 1 gram/day. Our results this underrepresented PWH are similar others defining hit, joint healthy, young white, male populations. However, bowl smaller than commonly reported. Over half sample greater gram/day previous almost quarter gram month.

Language: Английский

Citations

0