Current Addiction Reports,
Journal Year:
2023,
Volume and Issue:
10(3), P. 458 - 471
Published: June 30, 2023
Abstract
Purpose
of
Review
This
narrative
review
summarises
cultural
aspects
cannabis
use
across
different
(sub)cultures,
nations,
and
gender,
racial,
ethnic
groups.
Specifically,
we
aimed
to
overview
historical
traditional
contexts
physical
mental
health-related
correlates,
as
well
emerging
cannabis-related
policies
their
impacts
on
medicinal
recreational
cannabis.
In
addition,
discuss
how
factors
may
affect
behaviours
sociocultural
underpinnings
disorder
trajectories.
Recent
Findings
Cannabis
is
the
most
widely
cultivated,
trafficked,
used
illicit
drug
worldwide,
although
being
legalised
in
many
jurisdictions.
More
than
4%
individuals
globally
have
last
year.
Being
traditionally
for
religious
ritualistic
purposes,
today
interwoven
with,
influenced
by,
social,
legal,
economic,
environments
which
often
differ
countries
cultures.
Notably,
empirical
data
distinct
are
lacking
selected
underrepresented
countries,
geographical
regions,
minority
Summary
Emerging
global
legislative
frameworks
related
impacted
prevalence
attitudes
toward
subcultures,
but
not
all
same
way.
Therefore,
it
remains
be
elucidated
why
cultures
terms
use.
order
understand
complex
bidirectional
relationships
between
cultures,
recommend
cross-cultural
study
its
consequences
inform
vulnerable
people,
clinical
practitioners,
legislators
from
world
regions.
Journal of Dual Diagnosis,
Journal Year:
2023,
Volume and Issue:
19(2-3), P. 71 - 96
Published: July 3, 2023
Objective:
Cannabis
use
is
increasingly
normalized;
psychosis
a
major
adverse
health
outcome.
We
reviewed
evidence
on
cannabis
use-related
risk
factors
for
outcomes
at
different
stages
toward
recommendations
reduction
by
individuals
involved
in
use.
Methods:
searched
primary
databases
pertinent
literature/data
2016
onward,
principally
relying
reviews
and
high-quality
studies
which
were
narratively
summarized
quality-graded;
developed
international
expert
consensus.
Results:
Genetic
risks,
mental
health/substance
problem
histories
elevate
the
risks
cannabis-related
psychosis.
Early
age-of-use-onset,
frequency-of-use,
product
composition
(i.e.,
THC
potency),
mode
other
substance
co-use
all
influence
risks;
protective
effects
of
CBD
are
uncertain.
Continuous
may
adversely
affect
psychosis-related
treatment
medication
effects.
Risk
factor
combinations
further
amplify
odds
outcomes.
Conclusions:
Reductions
identified
factors—short
abstinence—may
decrease
related
outcomes,
thereby
protect
users'
health.
Current Addiction Reports,
Journal Year:
2024,
Volume and Issue:
11(3), P. 371 - 383
Published: March 14, 2024
Abstract
Purpose
of
Review
This
narrative
review
provides
an
update
our
knowledge
on
the
relation
between
heavy
cannabis
use
and
disorder
(CUD)
brain
based
(f)MRI
studies
conducted
in
past
5
years.
Recent
Findings
Heavy
CUD
are
associated
with
structural
changes—particularly
volume—as
well
as
altered
resting-state
functional
connectivity
(RSFC)
several
networks
regions.
Task-based
fMRI
reveal
activity
users
compared
to
controls,
but
consistency
results
is
domain
dependent.
Heaviness
use,
status,
age,
sex,
tobacco
co-use
important
potential
moderators
effects
brain.
Summary
differences
structure
function,
causality
remains
unclear,
long-term
following
abstinence
require
further
investigation.
Considering
crucial
assess
individual
impact
use.
Psychopharmacology,
Journal Year:
2024,
Volume and Issue:
241(6), P. 1237 - 1244
Published: Feb. 26, 2024
As
cannabis
potency
and
use
are
increasing
in
newly
legalized
markets,
it
is
increasingly
important
to
measure
examine
the
effects
of
cannabinoid
exposure.
Addiction Biology,
Journal Year:
2021,
Volume and Issue:
27(1)
Published: Aug. 17, 2021
Despite
the
significant
societal
and
personal
burden
of
cannabis
use,
impact
long-term
use
Cannabis
Use
Disorder
(CUD)
on
white
matter
microstructure
is
still
unclear.
Previous
studies
show
inconsistent
findings,
in
part
due
to
heterogeneity
methodology,
variable
severity
potential
confounding
effects
other
mental
health
issues
substance
use.
The
goal
this
diffusion
tensor
imaging
(DTI)
study
was
compare
whole-brain
between
39
near
daily
users
28
controls
closely
matched
age,
sex,
alcohol
cigarette
health.
Within
group
users,
associations
recent
dependence
severity,
age
onset
duration
weekly
were
investigated.
White
did
not
differ
covary
with
or
Earlier
related
lower
fractional
anisotropy
(FA)
various
sections
right
inferior
longitudinal
fasciculus
uncinate
fasciculus.
These
findings
suggest
that
near-daily
does
necessarily
affect
microstructure,
but
vulnerability
may
be
higher
during
adolescence.
underscore
importance
sample
composition
warrant
further
investigate
moderating
role
brain.
Systematic Reviews,
Journal Year:
2025,
Volume and Issue:
14(1)
Published: Jan. 24, 2025
There
has
been
a
global
increase
in
the
use
of
cannabinoids
as
treatment
for
mental
health
(MH)
and
substance
disorders
(SUD).
In
2016,
an
Australian
government-funded
review
found
that
although
medicinal
accounted
small
reduction
MH
symptoms,
results
varied
according
to
study
design.
since
rise
randomised
controlled
trials
(RCTs)
aiming
examine
efficacy
SUD.
Therefore,
current
systematic
will
(a)
identify
all
RCTs
examining
treating
SUD,
(b)
provide
quantitative
or
narrative
synthesis
evidence
efficacy,
(c)
synthesise
adverse
event
data
harm.
Electronic
databases
(Ovid
MEDLINE,
PsychINFO,
Cochrane
Central
Register
Controlled
Clinical
Trials,
Database
Systematic
Reviews,
Embase)
were
searched
from
1980
24
May
2023.
The
adheres
Preferred
Reporting
Items
Reviews
Meta-Analysis
Guidelines.
Articles
be
screened
capture
peer-reviewed
evaluating
plant-based
pharmaceutical
reducing
SUD
among
people
any
age.
risk
bias
tool
2.0
used
assess
bias,
while
Grades
Recommendation,
Assessment,
Development
Evaluation
(GRADE)
quality
each
outcome.
Study
findings
disseminated
through
published
manuscripts,
conferences,
policy
guidelines.
registration
PROSPERO
CRD42023392718.
JAMA Neurology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 14, 2025
Importance
Cannabis
use
is
associated
with
short-term
memory
impairment
and
long-term
changes
in
brain
structure;
however,
little
known
about
whether
disordered
cannabis
an
increased
risk
of
a
dementia
diagnosis.
Objective
To
investigate
the
association
between
emergency
department
visits
or
hospitalizations
(acute
care
encounters)
due
to
future
Design,
Setting,
Participants
Population-based,
retrospective,
matched
cohort
study
using
health
administrative
data
from
Ontario,
Canada,
2008
2021
(with
follow-up
until
2022)
including
all
individuals
aged
45
105
years
living
Ontario
who
were
eligible
did
not
have
diagnosis
at
entry
(2
620
083
excluded).
Exposure
Individuals
incident
acute
use,
defined
International
Classification
Diseases
Related
Health
Problems,
Tenth
Revision
coding.
Main
Outcomes
Measures
We
used
cause-specific
adjusted
hazard
models
compare
new
diagnoses
(from
validated
algorithm)
(1)
all-cause
(excluding
cannabis),
(2)
general
population,
(3)
alcohol
use.
Results
The
included
6
086
794
individuals,
whom
16
275
(0.3%)
had
(mean
age,
55.2
[SD,
8.3]
years;
60.3%
male).
Annual
rates
5.0-fold
64
10.16
50.65
per
100
000)
26.7-fold
65
older
0.65
16.99
2021.
1.5-fold
3.9-fold
within
5
relative
population
same
age
sex,
respectively
(absolute
diagnosis:
5.0%
for
cannabis-related
care,
3.6%
1.3%
population).
After
adjustment
sociodemographics
chronic
conditions,
remained
elevated
those
(adjusted
ratio
[aHR],
1.23;
95%
CI,
1.09-1.39)
(aHR,
1.72;
1.38-2.15).
lower
than
0.69;
0.62-0.76).
Conclusions
Relevance
severe
enough
require
hospital-based
compared
population.
These
findings
important
implications
considering
increasing
among
adults.
International Journal of Mental Health and Addiction,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 16, 2025
Abstract
Cannabis
use
(CU)
is
increasing
among
adults
aged
≥
50.
Yet,
its
effects
on
mental
and
physical
health
remain
understudied.
We
investigated
the
association
between
CU
Using
data
from
2022
Behavioral
Risk
Factor
Surveillance
System,
Marijuana
Use
module,
we
included
55,108
individuals
50
through
weighted
descriptive
multivariable
multinomial
logistic
regression
analyses.
Findings
Results
showed
that
infrequent,
frequent,
daily
cannabis
users
were
more
likely
to
be
younger,
male,
either
never
married
or
divorced/separated,
out
of
workforce,
lack
insurance
coverage
than
non-users.
Adults
who
used
had
133%
increased
odds
reporting
14
days
poor
76%
in
past
30
days.
Study
findings
suggest
associated
with
health,
highlighting
need
for
screening
promoting
awareness
adverse
effects.
Evidence-based
guidelines
are
essential
supporting
this
population’s
health.
