Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 27(2), P. 683 - 696
Published: Nov. 11, 2024
Metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity increases risk of cardiovascular disease. This cohort study examines the prognostic value MASLD, across body weight categories, in a secondary preventative acute myocardial infarction (AMI) cohort.
Language: Английский
European Journal of Preventive Cardiology, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Abstract Aims The prediction of future trends in cardiovascular disease (CVD) mortality and their risk factors can assist policy-makers healthcare planning. This study aims to project geospatial CVDs underlying from 2025 2050. Methods results Using historical data on disability-adjusted life years (DALYs) the Global Burden Disease (GBD) 2019 study, encompassing period 1990 2019, Poisson regression was performed model DALYs associated with CVD its Subgroup analysis based GBD super-regions. Between 2050, a 90.0% increase prevalence, 73.4% crude mortality, 54.7% are projected, an expected 35.6 million deaths 2050 (from 20.5 2025). However, age-standardized prevalence will be relatively constant (−3.6%), decreasing (−30.5%) (−29.6%). In ischaemic heart remain leading cause (20 deaths) while high systolic blood pressure main factor driving (18.9 deaths). Central Europe, Eastern Asia super-region is set incur highest rate (305 per 100 000 population). Conclusion coming decades, global suggests that net effect summative preventative efforts likely continue unchanged. fall reflects improvement medical care following diagnosis. systems expect rapid rise driven by ageing populace. continued burden largely attributed atherosclerotic diseases. Registration Not applicable.
Language: Английский
Citations
46
Cardiovascular Diabetology, Journal Year: 2025, Volume and Issue: 24(1)
Published: Feb. 7, 2025
Emerging evidence has demonstrated the unfavourable cardiovascular risk of individuals with lean type 2 diabetes mellitus (T2DM). Our study aims to investigate prognostic value T2DM in patients acute myocardial infarction (AMI), stratified by sex. The cohort examines clinical characteristics and long-term outcomes AMI, four phenotypes based on body category—lean T2DM, non-lean non-T2DM non-T2DM. primary outcome was all-cause mortality. Cox regression model constructed associations mortality, adjusted for age, ethnicity, previous AMI type, chronic kidney disease, angiotensin converting enzyme inhibitor or receptor blockers, beta-blockers, smoking status. A 9545 examined, a mean follow-up duration 3.4 ± 2.4 years. Majority had phenotype (40.4%), followed (29.8%), (15.9%), (13.9%). In group, one-quarter (N = 1324), while vast majority (74.5%) non-lean. Individuals tended be female older. Patients highest rates heart failure (23.3%, p < 0.001), cardiogenic shock (9.1%, 0.036), mortality (32.6%, 0.001). that an independent predictor (adjusted hazard ratio [aHR] 1.171, 95% CI 1.040–1.319, 0.009) after adjustment. presence higher following present males (aHR 1.201, 1.037–1.391, 0.015), but not females 1.066, 0.869–1.308, 0.538). T2DM. although this association stronger than females.
Language: Английский
Citations
1
Clinical Research in Cardiology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 12, 2024
Language: Английский
Citations
1
International Urology and Nephrology, Journal Year: 2024, Volume and Issue: unknown
Published: June 5, 2024
Language: Английский
Citations
0
Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 27(2), P. 683 - 696
Published: Nov. 11, 2024
Metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity increases risk of cardiovascular disease. This cohort study examines the prognostic value MASLD, across body weight categories, in a secondary preventative acute myocardial infarction (AMI) cohort.
Language: Английский
Citations
0