Audiology Research,
Journal Year:
2024,
Volume and Issue:
14(2), P. 280 - 292
Published: March 1, 2024
Background:
The
subtotal
petrosectomy
procedure
may
be
useful
for
cochlear
implantation
in
selected
patient
groups.
Although
it
is
highly
effective,
complications
can
arise,
which
have
economic
implications
the
due
to
high
cost
of
device.
Therefore,
several
authors
attempted
identify
most
effective
concept
obliteration.
Methods:
We
present
a
pilot
descriptive
study
application
techniques
obliterating
cavities
after
using
temporoparietal
fascial
flap
(TPFF)
modified
with
injectable
platelet-rich
fibrin
(IPRF+)
three
implant
(CI)
patients.
Results:
Our
preserves
important
anatomical
structures,
such
as
temporalis
muscle,
covers
CI
receiver–stimulator.
Injection
IPRF+
also
increases
available
tissue
volume
obliteration
and
enhances
its
anti-inflammatory
regenerative
potential.
Conclusions:
To
best
our
knowledge,
use
TPFF
filling
cavity
has
not
been
adopted
SP
blind
sac
closure.
literature
review
experience
this
small
group
patients
suggest
that
procedure,
when
combined
injections,
reduce
risk
potential
infection
obliterated
cavity,
particularly
used
CI.
This
technique
applicable
only
cases
surgeons
are
convinced
middle
ear
purged
cholesteatoma.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(3), P. 79 - 79
Published: Feb. 22, 2025
The
use
of
blood
plasma,
fibrinogen
or
fibrin,
a
natural
biomaterial,
has
been
widely
studied
for
the
development
different
skin
tissue-engineered
products
and
other
dermatological
treatments.
This
systematic
review
reports
preclinical
clinical
studies
which
it
alone
combined
with
biomaterials
and/or
cells
treatment
several
conditions.
Following
PRISMA
2020
Guidelines,
147
have
revealed
that
this
biomaterial
as
wound
dressing
monolayer
(one
cell
type)
substitute
are
preferred
strategies,
mainly
excisional
surgical
wounds.
Moreover,
plasma
is
used
although
its
combination
such
agarose,
polyethylene
glycol
collagen
also
reported
to
increase
healing
potential.
However,
most
17
reviewed
evaluated
severely
burned
patients
bilayer
(two
types)
substitute.
Although
number
evaluating
increased
during
last
fifteen
years,
not
correlated
wide
variety
studies.
Its
safety
potential
proved;
however,
lack
standard
model
presence
approaches
meant
translation
environment
still
limited.
A
higher
should
be
carried
out
in
coming
years
set
strategy
each
disease.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(16), P. 12608 - 12608
Published: Aug. 9, 2023
In
recent
years,
several
types
of
platelet
concentrates
have
been
investigated
and
applied
in
many
fields,
particularly
the
musculoskeletal
system.
Platelet-rich
fibrin
(PRF)
is
an
autologous
biomaterial,
a
second-generation
concentrate
containing
platelets
growth
factors
form
membranes
prepared
from
blood
patients
without
additives.
During
tissue
regeneration,
contain
higher
percentage
leukocytes
flexible
net
as
scaffold
to
improve
cell
migration
angiogenic,
osteogenic,
antibacterial
capacities
during
regeneration.
PRF
enables
release
molecules
over
longer
period,
which
promotes
healing
The
potential
simulate
physiology
immunology
wound
also
due
high
concentrations
released
anti-inflammatory
cytokines
that
stimulate
vessel
formation,
proliferation,
differentiation.
These
products
used
safely
clinical
applications
because
their
origin
minimally
invasive
nature.
We
focused
on
narrative
review
therapy
its
effects
musculoskeletal,
oral,
maxillofacial
surgeries
dermatology.
explored
components
leading
biological
activity
published
preclinical
research
supports
application
therapy.
generally
use
adjuvant
for
various
chronic
muscle,
cartilage,
tendon
injuries.
Further
trials
are
needed
prove
benefits
utilizing
PRF.
Stem Cell Research & Therapy,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Aug. 15, 2024
Abstract
Androgenetic
alopecia
(AGA)
is
the
most
prevalent
type
of
hair
loss.
Its
morbility
mainly
psychological
although
an
increased
incidence
in
melanoma
has
also
been
observed
affected
subjects.
Current
drug
based
therapies
and
physical
treatments
are
either
unsuccessful
long
term
or
have
relevant
side
effects
that
limit
their
application.
Therefore,
a
new
therapeutic
approach
needed
to
promote
regenerative
enhancement
alternatives.
These
treatment
options,
focused
on
cellular
niche
restoration,
could
be
solution
impact
dihydrotestosterone
follicle
microenvironment.
In
this
context
emerging
such
as
Platelet-rich
plasma
fibrine
well
stem
cells
mesenchymal
cell
derivatives
(conditioned
medium
CM
exoxomes)
highlighting
evolving
landscape
restoration.
Nanotechnology
leading
way
AGA
through
design
bioinks
nanobiomaterials
whose
structures
being
configuring
huge
range
cases
by
means
3D
bioprinting.
Due
increasing
number
rapid
creation
advanced
alternatives
field,
extended
review
current
state
art
needed.
addition
provides
general
insight
which
intented
guidance
for
researchers
cutting
edge
recently
gaining
ground.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(21), P. 11553 - 11553
Published: Oct. 26, 2021
The
purpose
of
this
review
is
to
examine
the
latest
literature
on
use
autologous
platelet-rich
fibrin
as
a
drug
and
growth
factor
carrier
system
in
maxillofacial
surgery.
Autologous
(PRF)
unique
that
combines
properties
such
biocompatibility
biodegradability,
addition
containing
factors
peptides
provide
tissue
regeneration.
This
opens
up
new
horizons
for
all
beneficial
ingredients
blood
sample
biomedical
purposes.
By
itself,
PRF
has
an
unstable
effect
osteogenesis:
therefore,
advanced
approaches,
including
combination
with
materials
or
drugs,
are
great
interest
clinics.
main
advantage
delivery
systems
by
controlling
release,
high
concentrations
locally
fewer
side
effects
within
other
can
be
achieved.
especially
important
tissues
limited
supply,
bone
compared
soft
tissue.
ability
degrade
naturally
considered
its
"warehouse"
controlled
release
systems.
We
focusing
concentrate,
it
easy
manipulations
delivered
directly
surgical
site.
target
audience
researchers
medical
doctors
who
involved
development
research
PRFs
further
studies.
Likewise,
surgeons
their
work
treat
patients
advice
take
medicine
orally.
Dermatologic Surgery,
Journal Year:
2024,
Volume and Issue:
50(5), P. 446 - 452
Published: Feb. 20, 2024
BACKGROUND
Platelet-rich
plasma
(PRP)
and
its
combined
therapeutic
modalities
have
catalyzed
new
possibilities
in
dermatology;
however,
limitations
evidence
lack
of
consensus
remain
among
clinicians
regarding
optimal
composition,
protocol,
technique,
application.
OBJECTIVE
To
provide
an
update
analysis
the
for
PRP
hair
restoration
skin
rejuvenation
through
review
recent
available
data,
highlighting
controversies
expert
insights
to
guide
future
studies,
stimulate
discourse
innovations
benefitting
patients.
METHODS
A
structured
PubMed
publications
before
October
2023,
with
a
focus
on
literature
from
January
2020
2023.
RESULTS
AND
CONCLUSION
Growing
supports
utility
benefits
related
autologous
products
applications
hair,
strongest
androgenetic
alopecia
rejuvenation.
However,
this
is
limited
by
best
practices
protocols.
Randomized,
controlled
trials
uniform
metrics
comparing
outcomes
various
compositions
blood
products,
preparation
methods,
dosimetry,
frequency
treatments
are
still
required.
This
will
allow
medical
grow
beyond
realm
opinion
into
consensus,
standardization,
more
wide
spread
adoption
that
benefit
Cosmetics,
Journal Year:
2024,
Volume and Issue:
11(2), P. 49 - 49
Published: March 31, 2024
The
growing
interest
in
maintaining
a
youthful
appearance
has
encouraged
an
accelerated
development
of
innovative,
minimally
invasive
aesthetic
treatments
for
facial
rejuvenation
and
regeneration.
close
correlation
between
tissue
repair,
regeneration,
aging
paved
the
way
application
regenerative
medicine
principles
cosmetic
dermatology.
theoretical
substrates
applications
dermo-aesthetics
are
plentiful.
However,
dermatology
is
emerging
field
needs
more
data
vivo
trials
to
reach
consensus
on
standardization
methods.
In
this
review,
we
summarize
techniques
as
they
apply
dermatology,
suggesting
unexplored
fields
future
directions.
Journal of Cosmetic Dermatology,
Journal Year:
2024,
Volume and Issue:
23(8), P. 2524 - 2530
Published: April 20, 2024
Abstract
Background
Androgenetic
alopecia
(AGA)
is
a
major
cause
of
hair
loss
resulting
from
complex
interplay
between
various
genes
and
hormones
with
the
result
being
follicular
miniaturization
altered
cycle
dynamics.
Platelet‐rich
plasma
(PRP)
has
well‐established
role
as
adjunctive
therapy
in
AGA
but
there
are
many
limitations
it.
In
an
attempt
to
overcome
shortcomings
PRP,
liquid
platelet‐rich
fibrin
(PRF)
was
developed.
Aim
This
article
critically
reviews
protocol
for
preparation
clinical
outcomes
PRF.
Patients/Methods
The
articles
published
so
far
English
language
regarding
PRF
were
reviewed.
Results
Among
five
studies
analyzing
centrifugation
speeds
times,
three
favored
low‐speed
centrifugation,
whereas
two
did
not
support
this
methodology.
A
horizontal
centrifuge
may
be
preferred
over
fixed‐angle
Five
on
use
showed
significant
effect
AGA.
Conclusion
At
present,
no
consensus
Most
used
low
speed
less
time.
Larger
needed
determine
optimal
force
due
higher
yield
platelets,
lesser
shear
trauma
cells.
addition,
larger,
well‐designed
confirm
benefits
PRP.
Periodontology 2000,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 31, 2024
Abstract
This
narrative
review
summarizes
current
knowledge
on
the
use
of
autologous
platelet
concentrates
(APCs)
in
esthetic
medicine,
with
goal
providing
clinicians
reliable
information
for
clinical
practice.
APCs
contain
platelets
that
release
various
growth
factors
potential
applications
facial
and
dermatologic
treatments.
examines
several
APCs,
including
acne
scarring,
skin
rejuvenation,
melasma,
vitiligo,
stretchmarks,
peri‐orbital
peri‐oral
hair
regeneration
volumizing
effects
APC
gels.
A
systematic
literature
databases
(PubMed/MEDLINE)
was
conducted
up
to
October
2023
identify
randomized
controlled
trials
(RCTs)
English
language
rejuvenation
dermatology.
total
96
articles
were
selected
those
rich
plasma
(PRP),
plasma‐rich
(PRGF),
platelet‐rich
fibrin
(PRF).
Clinical
recommendations
gained
from
reviews
are
provided.
In
summary,
esthetics
is
a
promising
yet
relatively
recent
treatment
approach.
Overall,
majority
studies
have
focused
PRP
positive
outcomes.
Only
few
compared
versus
PRF
all
demonstrating
superior
outcomes
using
PRF.
The
existing
limitations
small
sample
sizes
lack
standardized
assessment
criteria.
Future
research
should
utilize
well‐designed
RCTs,
incorporating
appropriate
controls,
such
as
split‐face
comparisons,
protocols
usage,
optimal
number
sessions,
interval
between
objective
improvement
scores.
Nevertheless,
most
formulations
offer
an
ability
improve
parameters
concerns.
