Obesity Reviews,
Journal Year:
2023,
Volume and Issue:
24(8)
Published: June 19, 2023
Hypertension
is
a
primary
risk
factor
for
cardiovascular
disease.
Cardiovascular
disease
the
leading
cause
of
death
among
adults
worldwide.
In
this
review,
we
focus
on
two
most
critical
public
health
challenges
that
contribute
to
hypertension-obesity
and
excess
dietary
sodium
from
salt
(i.e.,
chloride).
While
independent
effects
these
factors
have
been
studied
extensively,
interplay
obesity
overconsumption
not
well
understood.
Here,
discuss
both
combined
given
their
contributions
vascular
dysfunction,
autonomic
dysregulation,
kidney
insulin
resistance.
We
role
ultra-processed
foods-accounting
nearly
60%
energy
intake
in
America-as
major
contributor
overconsumption.
highlight
influence
elevated
blood
pressure
presence
high-salt
diet
sensitivity).
Throughout
gaps
knowledge
should
be
filled
inform
us
prevention,
management,
treatment,
mitigation
strategies
addressing
challenges.
BMC Public Health,
Journal Year:
2022,
Volume and Issue:
22(1)
Published: Jan. 7, 2022
Little
is
known
about
the
burden
that
overweight
and
obesity
impose
on
Dutch
society.
The
aim
of
this
study
to
examine
in
terms
cost-of-illness
health-related
quality
life.
Annals of Internal Medicine,
Journal Year:
2024,
Volume and Issue:
177(5), P. ITC65 - ITC80
Published: May 1, 2024
Obesity
is
a
common
condition
and
major
cause
of
morbidity
mortality.
Fortunately,
weight
loss
treatment
can
reduce
obesity-related
complications.
This
review
summarizes
the
evidence-based
strategies
physicians
employ
to
identify,
prevent,
treat
obesity,
including
best
practices
diagnose
counsel
patients,
assess
address
burden
weight-related
disease
stigma,
secondary
causes
gain,
help
patients
set
individualized
realistic
goals
an
effective
plan.
Effective
treatments
include
lifestyle
modification
adjunctive
therapies
such
as
antiobesity
medications
metabolic
bariatric
surgery.
Obesity Reviews,
Journal Year:
2019,
Volume and Issue:
20(6), P. 795 - 804
Published: March 1, 2019
Summary
Obesity
is
a
worldwide
growing
problem.
When
confronted
with
obesity,
many
health
care
providers
focus
on
direct
treatment
of
the
consequences
adiposity.
We
plead
for
adequate
diagnostics
first,
followed
by
an
individualized
treatment.
provide
experience‐based
and
evidence‐based
practical
recommendations
(illustrated
clinical
examples),
to
detect
potential
underlying
diseases
contributing
factors.
Adult
patients
consulting
doctor
weight
gain
or
obesity
should
first
be
clinically
assessed
diseases,
such
as
monogenetic
syndromic
hypothyroidism,
(cyclic)
Cushing
syndrome,
polycystic
ovarian
syndrome
(PCOS),
hypogonadism,
growth
hormone
deficiency,
hypothalamic
obesity.
The
most
important
alarm
symptoms
genetic
are
early
onset
dysmorphic
features/congenital
malformations
without
intellectual
deficit,
behavioral
problems,
hyperphagia,
and/or
striking
family
history.
Importantly,
also
common
factors
investigated,
including
medication
(mainly
psychiatric
drugs,
(local)
corticosteroids,
insulin,
specific
β‐adrenergic
receptor
blockers),
sleeping
habits
quality,
crash
diets
yoyo‐effect,
smoking
cessation,
alcoholism.
Other
associated
conditions
include
mental
chronic
stress
binge‐eating
disorder
depression.Identifying
optimizing
factors,
other
may
not
only
result
in
more
effective
personalized
but
could
reduce
social
stigma
Frontiers in Nutrition,
Journal Year:
2020,
Volume and Issue:
7
Published: Nov. 19, 2020
Background:
COVID-19
is
a
global
challenge
to
healthcare.
Obesity
common
in
patients
with
and
seems
aggravate
disease
prognosis.
In
this
review
we
explore
the
link
between
obesity,
chronic
disease,
lifestyle
factors
immune
system,
propose
societal
interventions
enhance
immunity.
Search
Strategy
Selection
Criteria:
We
performed
three
literature
searches
using
keywords
(1)
coronavirus
AND
comorbidities,
(2)
comorbidities
(3)
system.
Results
were
screened
for
relevance
by
main
author
total
of
215
articles
thoroughly
analyzed.
Results:
The
relationship
obesity
unfavorable
prognosis
discussed
light
impact
on
Several
modifiable
render
us
susceptible
viral
infections.
context,
make
case
fostering
healthy
scale.
Conclusions:
Obesity,
additional
an
unhealthy
interactively
impair
function
increase
risk
severe
infectious
disease.
adverse
metabolic
endocrine
conditions,
system
geared
toward
inflammation.
Collective
effort
needed
ameliorate
scale
resistance
viruses
like
SARS-CoV-2.
Nutrients,
Journal Year:
2022,
Volume and Issue:
14(6), P. 1259 - 1259
Published: March 16, 2022
After
a
low-calorie
diet,
only
25%
of
patients
succeed
in
maintaining
the
result
weight
loss
for
long
time.
This
systematic
review
and
meta-analysis
aims
to
explore
whether
undergoing
intensive
intervention
during
maintenance
phase
have
greater
preservation
achieved
previous
slimming
than
controls.
A
bibliographic
search
was
conducted
using
PubMed,
Scopus,
Cochrane
databases
clinical
trials
randomised,
controlled
investigating
role
choice
weight-loss-maintenance
strategies.
Only
studies
with
follow-up
at
least
12
months
were
considered.
total
eight
studies,
1454
patients,
identified,
each
comparing
group
that
followed
more
protocol
control
group.
Our
metanalysis
highlighted
an
approach
even
could
be
important
ensure
success
following
weight-loss
period.
However,
it
should
pointed
out
improvement
not
so
different
from
trend
respective
controls,
non-statistically
significant
mean
difference
effect
size
(0.087;
95%
CI
−0.016
0.190
p
=
0.098).
finding,
along
observation
regain
half
selected
suggests
this
is
work
has
started
within
reinforced
phase.
The
problem
obesity
understood
as
process
education
healthy
lifestyle
balanced
diet
integrated
context
multidisciplinary
approach.
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(3), P. 408 - 408
Published: March 13, 2025
Worldwide,
nearly
40%
of
adults
are
overweight
and
13%
obese.
Health
consequences
excess
weight
include
cardiovascular
diseases,
type
2
diabetes,
dyslipidemia,
increased
mortality.
Treating
obesity
is
challenging
calorie
restriction
often
leads
to
rebound
gain.
Treatments
such
as
bariatric
surgery
create
hesitancy
among
patients
due
their
invasiveness.
GLP-1
medications
have
revolutionized
loss
can
reduce
body
in
obese
by
between
15%
25%
on
average
after
about
1
year.
Their
mode
action
mimic
the
endogenous
GLP-1,
an
intestinal
hormone
that
regulates
glucose
metabolism
satiety.
However,
drugs
carry
known
risks
and,
since
use
for
recent,
may
unforeseen
well.
They
a
boxed
warning
people
with
personal
or
family
history
medullary
thyroid
carcinoma
multiple
endocrine
neoplasia
syndrome
2.
Gastrointestinal
adverse
events
(nausea,
vomiting,
diarrhea)
fairly
common
while
pancreatitis
obstruction
rarer.
There
be
lean
mass
well
premature
facial
aging.
A
significant
disadvantage
using
these
high
rate
regain
when
they
discontinued.
Achieving
success
pharmacologic
treatment
then
weaning
avoid
future
negative
effects
would
ideal.
Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity,
Journal Year:
2024,
Volume and Issue:
29(1)
Published: Jan. 2, 2024
Abstract
Obesity
is
a
complex,
chronic
disease
requiring
multidisciplinary
approach
to
its
management.
In
clinical
practice,
body
mass
index
and
waist-related
measurements
can
be
used
for
obesity
screening.
The
estimated
prevalence
of
among
adults
worldwide
12%.
With
the
expected
further
increase
in
overall
prevalence,
clinicians
will
increasingly
managing
patients
with
obesity.
Energy
balance
regulated
by
complex
neurohumoral
system
that
involves
central
nervous
circulating
mediators,
which
leptin
most
studied.
functioning
these
systems
influenced
both
genetic
environmental
factors.
generally
occurs
when
genetically
predisposed
individual
lives
an
obesogenic
environment
long
period.
Cardiologists
are
deeply
involved
evaluating
Cardiovascular
risk
profile
one
important
items
quantified
understand
health
due
benefit
single
patient
obtain
weight
loss.
At
level,
appropriate
involvement,
detection
potential
causes,
tools
improve
outcomes.
near
future,
we
probably
have
new
pharmacological
at
our
disposal
facilitate
achieving
maintaining
However,
treatment
alone
cannot
cure
such
disease.
aim
this
paper
summarize
some
key
points
field,
as
definition
measurement
tools,
epidemiology,
main
mechanisms
underlying
energy
homeostasis,
consequences
focus
on
cardiovascular
diseases
paradox.
Level
evidence
V:
report
expert
committees.
PLoS ONE,
Journal Year:
2020,
Volume and Issue:
15(5), P. e0232990 - e0232990
Published: May 8, 2020
Background
Underlying
medical
causes
of
obesity
(endocrine
disorders,
genetic
cerebral
or
medication-induced
obesities)
are
thought
to
be
rare.
Even
in
specialized
pediatric
endocrinology
clinics,
low
diagnostic
yield
is
reported,
but
evidence
limited.
Identifying
these
vital
for
patient-tailored
treatment.
Objectives
To
present
the
results
a
systematic
workup
children
and
adolescents
referred
center.
Methods
This
prospective
observational
study.
Prevalence
underlying
was
determined
after
multidisciplinary,
including
growth
charts
analysis,
extensive
biochemical
hormonal
assessment
testing
all
patients.
Results
The
completed
n
=
282
Median
age
10.8
years
(IQR
7.7–14.1);
median
BMI
+3.7SDS
+3.3-+4.3).
In
54
(19%)
patients,
singular
cause
identified:
37
patients
obesity,
8
9
obesities.
total,
thirteen
different
disorders
were
diagnosed.
Obesity
onset
<5
(p
0.04)
hyperphagia
0.001)
indicators
causes,
only
without
intellectual
disability
(ID).
Patients
with
ID
more
often
had
history
neonatal
feeding
problems
0.003)
short
stature
0.005).
BMI-SDS
not
higher
0.52).
obesities
lower
height-SDS
than
rest
cohort.
Conclusions
our
knowledge,
this
first
study
report
aimed
at
identifying
endocrine,
genetic,
obesity.
We
found
that
variety
identified
19%
severe
childhood
Because
heterogeneity,
an
approach
needed
establish
facilitate
disease-specific,
