Soft tissue expansion using self-inflating osmotic hydrogel expanders prior to bone augmentation: healing and complications. Evidence-based review DOI Creative Commons

Adam Gade Ellesøe,

Rawand Shado, Ines Novo Pereira

et al.

BDJ Open, Journal Year: 2023, Volume and Issue: 9(1)

Published: Nov. 11, 2023

This review aims to assess complication rates, soft tissue gain, and bone gain associated with the use of self-inflating osmotic hydrogel expanders (SOHTEs) for expansion (STE).A comprehensive search on Pubmed Google Scholar databases was conducted identify human studies using SOHTEs STE; last searched in March 2023. Expansion phase details expander variables were documented. Complication reported each study also recorded. The inclusion criteria encompassed ranging from evidence levels II-IV (Oxford Centre Evidence-Based Medicine Levels Evidence), without specific date limits. For assessing bias randomized controlled trials (RCTs), a Risk Bias tool employed. synthesised results presented through tables, sunburst plots, bar charts.A total 13 identified, comprising 4 RCTs, 1 cohort study, 8 case-series. Employment yielded an overall rate 17% (24/140 sites), perforation accounting 9.3% (13/140) sites. Specific rates included dehiscence (1.4%, 2/140 paraesthesia infection sites). All (RCTs) categorised at Level II. remaining investigations primarily consisted IV case-series lacking controls. demonstrated some concerns towards bias.STE exhibit reduction complications augmentation scenarios inadequate coverage. Preliminary suggests potential benefits even cases sufficient tissue. Adherence procedural precautions may reduce risk perforations, further diminishing complications. Subsequent should incorporate individual patient their reports explore impact phases as well augmentation.

Language: Английский

Advances in the research of immunomodulatory mechanism of mesenchymal stromal/stem cells on periodontal tissue regeneration DOI Creative Commons

Dezhi Zhao,

Ruilin Yang,

Han-Xiao Wei

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 3, 2025

Periodontal disease is a highly prevalent worldwide that seriously affects people's oral health, including gingivitis and periodontitis. Although the current treatment of periodontal can achieve good control inflammation, it difficult to regenerate supporting tissues satisfactory therapeutic effect. In recent years, due tissue regeneration ability, research on Mesenchymal stromal/stem cells (MSCs) MSC-derived exosomes has been gradually deepened, especially its ability interact with microenvironment body in complex immunoregulatory network, which led many new perspectives strategies for diseases. This paper systematically reviews immunomodulatory (including bone immunomodulation) properties MSCs their role inflammatory microenvironment, summarizes pathways mechanisms by MSC-EVs have promoted lists potential areas future research, describes issues should be considered basic direction development "cell-free therapies" regeneration.

Language: Английский

Citations

2
Anti‐Wound Dehiscence and Antibacterial Dressing with Highly Efficient Self‐Healing Feature for Guided Bone Regeneration Wound Closure DOI Creative Commons
Shenghao Xue, Ning Tang, Cheng Zhou

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(16)

Published: Feb. 27, 2024

Guided bone regeneration (GBR) is a well-established technique for preserving and enhancing alveolar ridge structures. Success in GBR relies on fulfilling the Primary wound closure, Angiogenesis, Space maintenance, Stability (PASS) principles. Conventional methods, involving titanium meshes sutures, have drawbacks, including need secondary removal customization challenges. To address these issues, an innovative multifunctional dressing (MGD) based self-healing elastomer (PUIDS) introduced. MGD provides sutureless prevents food particle accumulation, maintains stable environment growth. It offers biocompatibility, bactericidal properties, effectiveness oral model. In summary, reliable, osteogenic GBR, aligning with PASS principles promoting superior post-surgery regeneration.

Language: Английский

Citations

6
Bone Formation and Maintenance in Oral Surgery: The Decisive Role of the Immune System—A Narrative Review of Mechanisms and Solutions DOI Creative Commons

Élisa Choukroun,

Maximilien Parnot,

Jérôme Surmenian

et al.

Bioengineering, Journal Year: 2024, Volume and Issue: 11(2), P. 191 - 191

Published: Feb. 16, 2024

Based on the evidence of a significant communication and connection pathway between bone immune systems, new science has emerged: osteoimmunology. Indeed, system considerable impact health diseases, as well formation during grafts its stability over time. Chronic inflammation induces excessive production oxidants. An imbalance levels oxidants antioxidants is called oxidative stress. This physio-pathological state causes both molecular cellular damage, which leads to DNA alterations, genetic mutations cell apoptosis, thus, impaired immunity followed by delayed or compromised wound healing. Oxidative stress experienced body affect regeneration maintenance around teeth dental implants. As remodeling are interconnected, loss consequence dysregulation. Therefore, oral tissue deficiencies such periodontitis peri-implantitis should be regarded diseases. Bone management strategies include biological surgical solutions. These protocols tend improve through antioxidant enhance prevent loss. narrative review aims highlight relationship inflammation, oxidation, in cavity. It intends help clinicians detect high-risk situations surgery propose clinical solutions that will patients’ responses treatment outcomes.

Language: Английский

Citations

5
Mass spectrometry‐based proteomic applications in dental implants research DOI Creative Commons
Tim Halstenbach, Annika Topitsch, Oliver Schilling

et al.

PROTEOMICS - CLINICAL APPLICATIONS, Journal Year: 2024, Volume and Issue: 18(3)

Published: Feb. 11, 2024

Abstract Dental implants have been established as successful treatment options for missing teeth with steadily increasing demands. Today, the primary areas of research in dental implantology revolve around osseointegration, soft and hard tissue grafting well peri‐implantitis diagnostics, prevention, treatment. This review provides a comprehensive overview current literature on application MS‐based proteomics implant research, highlights how explorative provided insights into biology peri‐implant tissues facilitated stratification between healthy diseased implants, enabling identification potential new diagnostic markers. Additionally, this illuminates technical aspects, recommendations future study designs based evidence.

Language: Английский

Citations

3
The Modified Coronally Advanced Tunnel Technique for Coverage of Mucosal Recessions at Dental Implants DOI Open Access
Anton Sculean,

Georgios Nikou,

Herbert Deppe

et al.

Journal of Esthetic and Restorative Dentistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

To clinically evaluate the outcomes following surgical coverage of single peri-implant mucosal recessions in aesthetic maxillary area by means modified coronally advanced tunnel (MCAT) and subepithelial connective tissue graft (SCTG). Eleven systemically healthy non-smoking patients (8 females) each presenting a recession anterior region were consecutively treated with MCAT conjunction SCTG. In all cases, facial was associated an impaired appearance. Before reconstructive surgery at 12 months postoperatively, clinical parameters assessed. The primary outcome variable mean (MRC). Healing uneventful cases. At months, statistically significant (p < 0.05) (MRC 94.71%) improvement aesthetics (pink score) obtained implants. Complete RC 10 out 11 (90.9%). treatment gain keratinized attached mucosa 0.05). present results demonstrate that can be successfully

Language: Английский

Citations

0
Evaluation of palatal mucosal thickness in maxillary posterior teeth using cone-beam computed tomography combined with intraoral scanning: a cross-sectional study on correlating factors DOI Creative Commons

Shaoqing Sun,

T Zhang,

Wenxi Zhao

et al.

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 22, 2025

Cone-beam computed tomography (CBCT) combined with intraoral scanning (IOS) technology was used to measure and analyze the variation patterns of palatal masticatory mucosa (PMM) in maxillary posterior region its correlation gender, gingival biotype (GB), bone thickness (PBT), thereby establishing a theoretical foundation for autogenous soft tissue augmentation procedures. A total 57 Han Chinese patients 342 affected teeth were included study. CBCT IOS data obtained all participants, 3D models constructed by segmenting images based on standardized parameters, followed alignment using reference points. Measurements conducted at predetermined intervals evaluate PMM, PBT, GB. The variability PMM from first premolar molar analyzed bilaterally age, GB t-tests Games-Howell post-hoc analysis. Pearson's test examined relationship between while linear regression utilized associations clinical factors such as PBT. There no statistically significant difference left right sides maxilla (P > 0.05). Overall, increased greater distance margin, differences observed specific measurement points different tooth positions. second exhibited greatest 6 mm, 8 10 mm. Gender had relatively minor impact PMM. Significant across age groups, middle-aged group showing compared younger < At 2 mm molar's identified PBT weak. Regression analysis revealed primary determinant gender exerting site-specific effects. proved effective measuring symmetrical distribution areas optimal graft harvesting. While found GB, or notably thicker individuals. This study presents comprehensive various positions distances facilitating identification donor sites autologous grafts. It highlights regional ethnic variations among validates use accurate, non-invasive measurements.

Language: Английский

Citations

0
Mesh‐assisted regenerated site for alveolar ridge preservation: A case report DOI
John Zaki

Clinical Advances in Periodontics, Journal Year: 2025, Volume and Issue: unknown

Published: April 20, 2025

Abstract Background The proposed technique utilizes the osteoconductive regenerative properties of bone‐substitute materials (BSMs) and space‐maintaining function titanium mesh to restore alveolar ridge at extraction sites with lost labial plates in a single procedure. This approach may reduce need for extensive augmentation procedures, shorten treatment duration, minimize complications, potentially lower overall costs patients. Methods Both patients presented hopeless dentition, characterized by chronic infection loss plates. To regenerate ridge, was utilized combination layered application xenograft allograft BSMs. success this depended on stabilization, thorough site debridement, absence soft‐tissue tension. Results effectively restored regenerated sufficient bone accommodate dental implants. Significant regeneration achieved both cases, minimal complications. In one case, minor exposure occurred; however, it did not affect healing managed during re‐entry surgery. Conclusion It represents novel preservation plates, even presence infection. However, future studies sound methodology, larger sample sizes, long follow‐up periods are recommended validate these findings. Key points Mesh‐Assisted Regenerated Site (MARS) restores combining substitutes augmentation, long‐term costs. depends minimally traumatic extraction, meticulous socket careful soft tissue management, precise placement under optimal magnification. Although effective, has limitations, including potential vertical loss, time‐consuming possible additional occasional challenges retrieval, risk, all which compromise implant success. Proper case selection essential mitigate optimize clinical outcomes. Plain language summary When teeth removed, surrounding can shrink. Techniques preserve area, known as preservation, help prevent shrinkage. uses specialized rebuild areas where front portion is missing. author used bone. steps included stabilizing mesh, thoroughly cleaning out any infection, layering materials, ensuring gum overly tight. successfully reconstructed missing bone, making place standard cases showed significant growth issues. small part exposed but impact addressed rebuilt long‐standing shows promise preserving regenerating areas, more needed confirm results improve method.

Language: Английский

Citations

0
Does platelet‐rich fibrin enhance the outcomes of peri-implant soft tissues? A systematic review DOI Creative Commons
Enrica Giammarinaro, Nicola Baldini, Ugo Covani

et al.

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 22, 2025

Language: Английский

Citations

0
The Potential Value of Probiotics after Dental Implant Placement DOI Creative Commons
Jia Xu,

Chenfeng Chen,

Shuaiqi Gan

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(7), P. 1845 - 1845

Published: July 20, 2023

Dental implantation is currently the optimal solution for tooth loss. However, health and stability of dental implants have emerged as global public concerns. implant placement, healing surgical site, osseointegration, bone tissues, prevention peri-implant diseases are challenges faced in achieving long-term implants. These been ongoing concerns field oral implantation. Probiotics, beneficial microorganisms, play a significant role body by inhibiting pathogens, promoting tissue homeostasis, facilitating regeneration, modulating immune-inflammatory levels. This review explores potential probiotics addressing post-implantation challenges. We summarize existing research regarding importance managing advocate further into their applications.

Language: Английский

Citations

6
Post-extraction volumetric analysis of alveolar ridge contour using subepithelial connective tissue graft in esthetic zone: a randomized controlled clinical trial DOI Creative Commons
Nourhan Gamal, Nesma Shemais, Marwa Alnawawy

et al.

Clinical Oral Investigations, Journal Year: 2023, Volume and Issue: 27(11), P. 6503 - 6512

Published: Sept. 19, 2023

The aim of this randomized clinical trial was to assess the alveolar ridge contour after soft tissue augmentation using subepithelial connective graft (SCTG) buccal fresh extraction sockets in patients with thin bone, versus minimally-traumatic followed by spontaneous healing solely.

Language: Английский

Citations

6