Frontiers in Oncology,
Journal Year:
2021,
Volume and Issue:
11
Published: Dec. 14, 2021
The
aim
of
the
study
was
to
develop
an
algorithm
predict
postoperative
pneumonia
among
elderly
patients
with
lung
cancer
after
video-assisted
thoracoscopic
surgery.
We
analyzed
3,009
from
Thoracic
Perioperative
Database
for
Geriatrics
in
our
hospital
and
finally
enrolled
1,585
(age≧65
years)
treated
included
were
randomly
divided
into
a
training
group
(n
=
793)
validation
792).
Patients
used
screening
up
30
potential
risk
factors,
internally
validate
algorithm.
External
achieved
external
dataset
enrolling
165
surgery
two
hospitals
China.
Of
all
patients,
9.15%
(145/1,585)
suffered
Geriatrics,
10.30%
(17/165)
had
dataset.
consisted
seven
variables,
including
sex,
smoking,
history
chronic
obstructive
pulmonary
disease
(COPD),
duration,
leukocyte
count,
intraoperative
injection
colloid,
hormone.
C-index
receiver
operating
characteristic
curve
(AUROC)
0.70
group,
0.67
internal
0.71
dataset,
corresponding
calibration
slopes
0.88
(95%
confident
interval
[CI]:
0.37-1.39),
0.90
CI:
0.46-1.34),
1.03
0.24-1.83),
respectively.
actual
probabilities
5.14%
(53/1031)
low-risk
15.07%
(71/471)
medium-risk
25.30%
(21/83)
high-risk
(p
<
0.001).
can
be
useful
prognostic
tool
developing
Cancers,
Journal Year:
2023,
Volume and Issue:
15(22), P. 5440 - 5440
Published: Nov. 16, 2023
Lung
carcinoids
are
neuroendocrine
tumors,
categorized
as
typical
or
atypical
based
on
their
histological
appearance.
While
most
of
these
tumors
slow-growing
neoplasms,
they
still
possess
malignant
potential.
Many
patients
diagnosed
incidentally
chest
X-rays
CT
scans.
Presenting
symptoms
include
cough,
hemoptysis,
wheezing,
dyspnea,
and
recurrent
pneumonia.
Endocrine
symptoms,
such
carcinoid
syndrome
ectopic
Cushing’s
syndrome,
rare.
Surgery
is
the
primary
treatment
should
be
considered
in
all
with
localized
disease,
even
when
thoracic
lymph
node
metastases
present.
Patients
distant
may
treated
somatostatin
analogues,
chemotherapy,
preferably
temozolomide-based,
mTOR
inhibitors,
peptide
receptor
radionuclide
therapy
(PRRT)
177Lu-DOTATATE.
Most
have
an
excellent
prognosis.
Poor
prognostic
factors
histology
at
diagnosis.
Long-term
follow-up
mandatory
since
occur
late.
PubMed,
Journal Year:
2024,
Volume and Issue:
27(2), P. 122 - 133
Published: Jan. 1, 2024
Lung
cancer
is
one
of
the
leading
causes
death
among
all
deaths.
This
classified
into
two
different
histological
subtypes:
non-small
cell
lung
(NSCLC),
which
most
common
subtype,
and
small
(SCLC),
aggressive
subtype.
Understanding
molecular
characteristics
has
expanded
our
knowledge
cellular
origins
pathways
affected
by
each
these
subtypes
contributed
to
development
new
therapies.
Traditional
treatments
for
include
surgery,
chemotherapy,
radiotherapy.
Advances
in
understanding
nature
specificity
have
led
immunotherapy,
newest
specialized
treatment
cancer.
Each
advantages
disadvantages
side
effects.
Today,
combination
therapy
reduces
effects
increases
speed
recovery.
Despite
significant
progress
that
been
made
last
decade,
further
research
drugs
therapies
needed
extend
clinical
benefits
improve
outcomes
In
this
review
article,
we
discussed
their
combinations
from
advanced
newest.
BMC Anesthesiology,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Jan. 7, 2025
Various
analgesic
techniques
have
been
applied,
the
pain
after
video
assisted
thoracic
surgery
(VATS)
is
still
challenging
for
anesthesiologists.
Paracetamol
provide
efficacy
in
many
surgeries.
However,
clinical
evidence
lung
with
regional
block
remain
limited.
This
monocentric
double-blind
randomized
controlled
trial
investigates
of
paracetamol
VATS
block.
A
total
90
patients
were
to
receive
(1
g)
or
normal
saline.
Erector
Spinae
Plane
Block
and
Intercostal
Nerve
applied
during
surgery.
The
Visual
Analogue
Scales
(VAS)
score
was
measured
PACU
as
well
6,
12,
24,
48
h
postoperatively.
And
dose
rescue
analgesics
administered
morphine
milligram
equivalents
(MME),
satisfaction
score,
length
hospital
stays,
incidence
nausea
vomiting
also
recorded.
VAS
at
each
time
point,
primary
endpoint,
did
not
differ
between
groups
(3.09
±
2.14
vs.
2.53
1.67,
p
=
0.174
PACU;
4.56
2.80
4.06
2.46,
0.368
6
h;
3.07
1.98
3.44
2.48,
0.427
12
2.10
2.00
2.49
2.07,
24
1.93
1.76
2.39
1.97,
0.251
postoperatively).
Satisfaction
scores
(4.37
0.76
4.14
0.88,
0.201),
(35.6%
37.8%,
0.827),
hypotension
(2.2%
0.0%,
0.317),
bradycardia
(6.7%
2.2%,
0.309)
reported
similar
rates.
one
gram
ESPB
ICNB
proven.
Thus,
caution
should
be
exercised
when
prescribing
control
VATS.
this
registered
on
Clinical
Research
Information
Service
(CRIS),
Republic
Korea
(KCT0008710).
Registration
date:
17/08/2023.
Cancer Reports,
Journal Year:
2025,
Volume and Issue:
8(3)
Published: March 1, 2025
ABSTRACT
Introduction
Globally,
lung
cancer
is
one
of
the
most
commonly
diagnosed
cancers
and
continues
to
take
lead
in
cancer‐related
mortality
rates.
This
study
aims
provide
latest
statistics
on
clinical,
histopathological,
epidemiological
features
patients
who
underwent
surgical
resection
referral
hospitals
Southern
Iran.
Method
In
this
retrospective
study,
records
all
with
operable
primary
secondary
Shiraz
hospitals,
located
Iran
from
November
2009
May
2022
were
screened.
Data
demographic,
surgical,
pathological
characteristics
analyzed
by
SPSS
software.
Results
A
total
232
cancer,
including
150
(64.7%)
cases
82
(35.3%)
cases,
249
operations.
The
mean
age
was
56.70
±
13.99
45.56
18.88,
respectively
(
p
<
0.001).
Males
accounted
for
54.0%
58.5%
patients,
respectively.
Adenocarcinoma
frequent
pathology,
while
sarcomas
common
metastatic
lesions.
predominant
presenting
symptoms
cough
n
=
75,
75.0%)
dyspnea
31,
59.7%)
Involvement
right
more
both
groups
(65.5%
53.1%
respectively).
performed
surgeries
lobectomy
(69.9%)
limited
(69.8%)
lesions,
Cigarette
smoking
extensive
had
a
significant
association
in‐hospital
rate
0.012
0.009
overall
3.6%
9).
Conclusion
Surgical
interventions
mostly
men
histopathologic
subtypes
adenocarcinoma,
soft
tissue
sarcoma,
colon
cancer.
Smoking
accompany
higher
risk
short‐term
postoperative
mortality.
Clinical Rehabilitation,
Journal Year:
2020,
Volume and Issue:
35(6), P. 840 - 850
Published: Dec. 14, 2020
Objective:
To
compare
the
postoperative
outcomes
of
inspiratory
muscle
training
and
aerobic
exercise,
along
with
standard
care,
on
lung
cancer
patients
undergoing
video-assisted
thoracoscopic
surgery
(VATS).
Design:
A
parallel-group,
single-blind
randomized
clinical
trial
Setting:
Thoracic
ward
outpatient
clinic
in
a
teaching
hospital
Subjects:
Overall
63
underwent
VATS
were
randomly
assigned
to
triaging
(TG,
n
=
32)
or
control
group
(CG,
31).
total
54
26;
CG,
28)
completed
study.
Intervention:
TG:
six-week
threshold
exercise.
CG:
care.
Main
measures:
Maximum
pressure
(PImax),
maximum
expiratory
(PEmax)
expansion
volume,
6-min
walking
test
(6MWT)
performed
day
chest
tube
removal
(baseline),
2,
6,
12
weeks
postoperatively.
Results:
The
TG
showed
significant
improvement
PImax
at
week
6
(71.6
±
34.9
vs.
94.3
32.8
cmH
2
O,
P
0.018),
PEmax
(70.9
24.3
90.9
28.2
0.015)
(76.1
20.2
98.6
35.3
0.012),
volume
(1080
433
vs
1457
624
mL,
0.02)
(1200
387
1885
678
<
0.001),
addition
6MWT
(332
78
412
74
m,
0.002),
(360
70
419
60
0.007)
58
402
65
0.036).
Conclusion:
six
exercise
had
improved
respiratory
strength
postoperatively
after
as
early
weeks.
