Blackcurrant Alters Physiological Responses and Femoral Artery Diameter during Sustained Isometric Contraction

Nutrients, Journal Year: 2017, Volume and Issue: 9(6), P. 556 - 556

Published: May 29, 2017

Blackcurrant is rich in anthocyanins that may affect exercise-induced physiological responses. We examined tissue oxygen saturation, muscle activity, cardiovascular responses and femoral artery diameter during a submaximal sustained isometric contraction. In randomised, double-blind, crossover design, healthy men (n = 13, age: 25 ± 4 years, BMI: 3 kg·m−2, mean SD) ingested New Zealand blackcurrant (NZBC) extract (600 mg∙day−1 CurraNZ™) or placebo (PL) for 7-days separated by 14-days washout. Participants produced maximal voluntary contractions (iMVC) 120-s 30%iMVC of the quadriceps with electromyography (EMG), near-infrared spectroscopy, hemodynamic ultrasound recordings. There was no effect NZBC on iMVC (NZBC: 654 73, PL: 650 78 N). During extract, total peripheral resistance, systolic, diastolic, arterial pressure were lower increased cardiac output stroke volume. With EMG root square vastus medialis saturation higher haemoglobin. 30%iMVC, at 30 (6.9%), 60 (8.2%), 90 (7.7%) 120 s (6.0%). Intake altered responses, activity quadriceps. The present study provides insight into potential mechanisms enhanced exercise performance intake blackcurrant.

Language: Английский

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In Vivo Assessment of Mitochondrial Dysfunction in Clinical Populations Using Near-Infrared Spectroscopy

Frontiers in Physiology, Journal Year: 2017, Volume and Issue: 8

Published: Sept. 14, 2017

The ability to sustain submaximal exercise is largely dependent on the oxidative capacity of mitochondria within skeletal muscle, and impairments in metabolism have been implicated many neurologic cardiovascular pathologies. Here we review studies which demonstrated utility Near-infrared spectroscopy (NIRS) as a method evaluating muscle mitochondrial dysfunction clinical human populations. NIRS has previously used noninvasively measure tissue oxygen saturation, but recent using post-exercise recovery kinetics metabolism. In comparison historical methods measuring metabolic vivo, provides more versatile economical humans. These advantages generate great potential for applicability means

Language: Английский

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Effects of montmorency tart cherry (L. Prunus Cerasus) consumption on nitric oxide biomarkers and exercise performance

Scandinavian Journal of Medicine and Science in Sports, Journal Year: 2018, Volume and Issue: 28(7), P. 1746 - 1756

Published: March 22, 2018

The purpose of this study was to investigate the effects Montmorency tart cherry juice ( MC ) on nitric oxide NO biomarkers, vascular function, and exercise performance. In a randomized, double‐blind, placebo PLA )‐controlled, crossover study, 10 trained cyclists (mean ± SD ; O 2peak 59.0 7.0 mL/kg/min) acutely ingested 30 mL either or following dietary restrictions polyphenol‐rich compounds completed 6‐minutes moderate‐ severe‐intensity cycling bouts 1.5 hour post‐ingestion 2 occasions for each experimental condition. test continued exhaustion 1 occasion immediately followed by 60‐seconds all‐out sprint other occasion. Blood pressure, pulse wave measures, tissue oxygenation index, plasma nitrite concentration were assessed pre‐ post‐ingestion. Time not different between conditions P > .05), but peak power over first 20 seconds (363 42 vs 330 26 W) total work during (21 3 19 kJ 10% higher in trial compared < .05). Systolic blood pressure 5 mm Hg lower post‐ supplementation There no differences concentration, trials These results suggest that acute with can improve some aspects performance, specifically end‐sprint cyclists.

Language: Английский

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Peripheral impairments of oxidative metabolism after a 10‐day bed rest are upstream of mitochondrial respiration

The Journal of Physiology, Journal Year: 2021, Volume and Issue: 599(21), P. 4813 - 4829

Published: Sept. 10, 2021

In order to identify peripheral biomarkers of impaired oxidative metabolism during exercise following a 10-day bed rest, 10 males performed an incremental (to determine peak pulmonary V̇O2 (V̇O2 p)) and moderate-intensity exercises, before (PRE) after (POST) rest. Blood flow response was evaluated in the common femoral artery by Eco-Doppler 1 min passive leg movements (PLM). The intramuscular matching between O2 delivery utilization near-infrared spectroscopy (NIRS). Mitochondrial respiration ex vivo high-resolution respirometry isolated muscle fibres, NIRS evaluation skeletal m) recovery kinetics. Resting m estimated NIRS. Peak p lower POST vs. PRE. area under blood time curve PLM smaller (P = 0.03) (274 ± 233 mL) PRE (427 291). An increased overshoot deoxygenation metabolic transition identified POST. Skeletal citrate synthase activity not different 0.11) (131 16 nmol min-1 mg-1 ) (138 19). Maximal ADP-stimulated mitochondrial (66 18 pmol s-1 72 14 (PRE), P 0.41) affected Apparent Km for ADP sensitivity reduced 0.04). constant 0.79) (22 6 s) 6). 25% 0.006). Microvascular-endothelial function whereas mass (both vivo) were unaffected or slightly enhanced. KEY POINTS: Ten days horizontal rest exercise. Microvascular impairments methods. (evaluated both unchanged even improved (i.e. enhanced submaximal [ADP]). oxygen uptake significantly suggesting that catabolic processes induced rest/inactivity are less energy-consuming than anabolic ones.

Language: Английский

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Efficient and thermally stable broadband near-infrared emission in a garnet Gd₃In₂Ga₃O₁₂:Cr³⁺ phosphor

Dalton Transactions, Journal Year: 2022, Volume and Issue: 51(43), P. 16757 - 16763

Published: Jan. 1, 2022

Compact broadband near-infrared (NIR) light sources generated by phosphor-converted light-emitting diodes (pc-LEDs) have attracted considerable interest in emerging smart NIR spectroscopy applications. However, discovering a highly efficient and thermally stable phosphor still remains significant challenge. Here, we report new garnet phosphor, Gd3In2Ga3O12:Cr3+, which has emission peaking at 780 nm with full-width half maximum (FWHM) of 124 nm. The optimized Cr3+-doping concentration this material is particularly high (9 mol%), resulting quantum yield absorption efficiency 85.3% 49.1%, respectively. Moreover, 87.7% the initial intensity can be retained when heating up to 150 °C, demonstrating excellent thermal stability material. Fabricating prototype device using as-prepared combination blue LED chip, an output power (33.7 mW) photoelectronic conversion 12.0% achieved under 100 mA driving current. These results indicate that Gd3In2Ga3O12:Cr3+ may great potential for pc-LED

Language: Английский

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