Optical imaging and spectroscopy for the study of the human brain: status report

Neurophotonics, Journal Year: 2022, Volume and Issue: 9(S2)

Published: Aug. 30, 2022

This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit novel methods to explore brain health function. While first focused on neurophotonic tools mostly applicable animal studies, here, we highlight optical spectroscopy imaging relevant noninvasive human studies. We outline current state-of-the-art technologies software advances, most recent impact these neuroscience clinical applications, identify areas where innovation needed, provide outlook for future directions.

Language: Английский

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Wearable, high-density fNIRS and diffuse optical tomography technologies: a perspective

Neurophotonics, Journal Year: 2023, Volume and Issue: 10(02)

Published: May 17, 2023

Recent progress in optoelectronics has made wearable and high-density functional near-infrared spectroscopy (fNIRS) diffuse optical tomography (DOT) technologies possible for the first time. These have potential to open new fields of real-world neuroscience by enabling neuroimaging human cortex at a resolution comparable fMRI almost any environment population. In this perspective article, we provide brief overview history current status fNIRS DOT approaches, discuss greatest ongoing challenges, our thoughts on future remarkable technology.

Language: Английский

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Inhibiting responses under the watch of a recently synchronized peer increases self-monitoring: evidence from functional near-infrared spectroscopy

Open Biology, Journal Year: 2024, Volume and Issue: 14(2)

Published: Feb. 1, 2024

Developing motor synchrony with a peer (through interventions such as the mirror game) can yield collaborative, cognitive and social benefits. However, it is also well established that observation by an audience improve cognition. The combined relative advantages offered synchronization effects are not yet understood. It important to address this gap determine extent which synchronizing activities might interact positive of audience. In preregistered study, we investigate response inhibition may be improved when observed after peer. We compare behavioural cortical (functional near-infrared spectroscopy; fNIRS) measures between synchronized non-synchronized dyads find presence peer-audience introduces speed-accuracy trade-off, consisting slower reaction times accuracy. This co-occurs activation in bilateral inferior frontal middle prefrontal cortices, implicated monitoring maintenance alignment. Our findings have implications for carers support people, who benefit from rehabilitating skills clinical settings.

Language: Английский

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Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study

Journal of Integrative Neuroscience, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 7, 2025

Background: Observation, execution, and imitation of target actions based on mirror neuron network (MNN) have become common physiotherapy strategies. Electrical stimulation (ES) is a intervention to improve muscle strength motor control in rehabilitation treatments. It possible enhance MNN’s activation by combining execution (ME) (MI) with ES simultaneously. This study aims reveal whether could impact cortical during ME MI. Methods: We recruited healthy individuals assigned them randomly the group (CG) or experiment (EG). Participants EG performed MI tasks ES, while participants CG same two sham ES. utilized functional near-infrared spectroscopy (fNIRS) detect brain MNN without randomized block design paradigm was designed. Descriptive analysis oxy-hemoglobin (HbO) deoxy-hemoglobin (HbR) were used show hemoglobin (Hb) concentration changes after different event onsets both EG, linear mixed-effects model (LMM) HbO data employed analyze effect MNN. Results: A total 102 adults 72 participants’ analysed final report. The averaged Hb showed that increased HbR decreased most regions groups. LMM results can significantly inferior frontal gyrus, middle precentral gyrus MI, supplementary area, parietal lobule, superior temporal gyri activation, but statistical significance. Although did not reach significance ME, still positive effects overall activations. Conclusions: In this study, we present potential novel approaches combines strategies low-frequency activation. Our revealed has increase areas, providing evidence for related rehabilitative interventions device development. Clinical Trial Registration: registered China Registration Center (identifier: ChiCTR2200064082, 26, September 2022, https://www.chictr.org.cn/showproj.html?proj=178285).

Language: Английский

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NIRS-BIDS: Brain Imaging Data Structure Extended to Near-Infrared Spectroscopy

Scientific Data, Journal Year: 2025, Volume and Issue: 12(1)

Published: Jan. 27, 2025

Language: Английский

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Using preregistration as a tool for transparent fNIRS study design

Neurophotonics, Journal Year: 2023, Volume and Issue: 10(02)

Published: March 8, 2023

The expansion of functional near-infrared spectroscopy (fNIRS) methodology and analysis tools gives rise to various design analytical decisions that researchers have make. Several recent efforts developed guidelines for preprocessing, analyzing, reporting practices. For the planning stage fNIRS studies, similar guidance is desirable. Study preregistration helps transparently document study protocols before conducting study, including materials, methods, analyses, thus, others verify, understand, reproduce a study. Preregistration can thus serve as useful tool transparent, careful, comprehensive design.We aim create guide on steps involved in studies provide template specified studies.The presented has strong focus specific requirements, associated provides examples based continuous-wave (CW) conducted humans. These can, however, be extended other types studies.On step-by-step basis, we walk user through key methodological analysis-related aspects central design. include items CW, task-based but also sections are general importance, an in-depth elaboration sample size planning.Our introduces these open science community, providing with overview specification recommendations planning. As such it used preregister or merely transparent

Language: Английский

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Cross-modal functional connectivity supports speech understanding in cochlear implant users

Cerebral Cortex, Journal Year: 2022, Volume and Issue: 33(7), P. 3350 - 3371

Published: Aug. 20, 2022

Abstract Sensory deprivation can lead to cross-modal cortical changes, whereby sensory brain regions deprived of input may be recruited perform atypical function. Enhanced responses visual stimuli observed in auditory cortex postlingually deaf cochlear implant (CI) users are hypothesized reflect increased activation language regions, but it is unclear if this activity “adaptive” or “mal-adaptive” for speech understanding. To determine correlated with better understanding CI users, we assessed task-related and functional connectivity cortices non-speech (n = 14) normal-hearing listeners 17) used near-infrared spectroscopy measure hemodynamic responses. We visually presented investigate neural processes related linguistic content that show beneficial effects. Specifically, an increase between the left cortices—presumed primary sites processing—was positively users’ abilities understand background noise. Cross-modal adaptive a distributed, multimodal network, enhance

Language: Английский

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Reducing false discoveries in resting-state functional connectivity using short channel correction: an fNIRS study

Neurophotonics, Journal Year: 2022, Volume and Issue: 9(01)

Published: Jan. 18, 2022

Significance: Functional near-infrared spectroscopy (fNIRS) is a neuroimaging tool that can measure resting-state functional connectivity; however, non-neuronal components present in fNIRS signals introduce false discoveries connectivity, which impact interpretation of networks. Aim: We investigated the effect short channel correction on connectivity by removing from long data. hypothesized be reduced, hence improving discriminability networks known, different strengths. Approach: A principal component analysis-based technique was applied to data 10 healthy adult subjects. Connectivity analyzed using magnitude-squared coherence pairs groups homologous and control brain regions, are known differ connectivity. Results: By correction, significant reduction observed for oxy-hemoglobin concentration changes frequency bands associated with overlap Mayer wave frequencies. The results showed reduced spurious correlations measures improved between groups. Conclusions: Resting-state analysis performs better than without its ability distinguish distinct characteristics.

Language: Английский

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Within-session Reliability of fNIRS in Robot-assisted Upper-limb Training

IEEE Transactions on Neural Systems and Rehabilitation Engineering, Journal Year: 2024, Volume and Issue: 32, P. 1302 - 1313

Published: Jan. 1, 2024

Functional near-infrared spectroscopy (fNIRS) seems opportune for neurofeedback in robot-assisted rehabilitation training due to its noninvasive, less physical restriction, and no electromagnetic disturbance.Previous research has proved the cross-session reliability of fNIRS responses non-motor tasks (e.g., visual stimuli) fine-motor finger tapping).However, it is still unknown whether remain reliable 1) gross-motor tasks, 2) within a session, 3) different parameters.Hence, this study aimed investigate within-session parameters.Ten healthy participants were recruited conduct right elbow extensionflexion three modes.The Passive mode was fully motor-actuated, while Active1 Active2 modes involved active engagement with resistance levels.FNIRS data identical runs used assess terms map-(R 2 ) cluster-wise (R overlap spatial reproducibility intraclass correlation (ICC) temporal features.The results revealed good up 0.69, R 0.68) at subject level.Besides, reliabilities Slope, Max/Min, Mean between excellent (0.60 < ICC 0.86).We also found that positively correlated intensity mode, except HbO mode.Overall, our demonstrated responses, suggesting as constructing closed-loop systems.

Language: Английский

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Lights on music cognition: A systematic and critical review of fNIRS applications and future perspectives

Brain and Cognition, Journal Year: 2024, Volume and Issue: 180, P. 106200 - 106200

Published: June 21, 2024

Research investigating the neural processes related to music perception and production constitutes a well-established field within cognitive neurosciences. While most neuroimaging tools have limitations in studying complexity of musical experiences, functional Near-Infrared Spectroscopy (fNIRS) represents promising, relatively new tool for both laboratory ecological settings, which is also suitable typical pathological populations across development. Here we systematically review fNIRS studies on cognition, highlighting prospects potentialities. We include an overview basic theory, together with brief comparison characteristics other tools. Fifty-nine meeting inclusion criteria (i.e., using as primary stimulus) are presented five thematic sections. Critical discussion methodology leads us propose guidelines good practices aiming robust signal analyses reproducibility. A continuously updated world map proposed, including information from criteria. It provides organized, accessible, updatable reference database, could serve catalyst future collaborations community. In conclusion, shows potential music, particularly contexts special populations, aligning current research priorities cognition.

Language: Английский

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