Bi-directional communication between intrinsic enteric neurons and ILC2s inhibits host defense against helminth infection

Immunity, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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The gut–organ axis: Clinical aspects and immune mechanisms

Allergology International, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

The gut-brain axis exemplifies the bidirectional connection between intestines and brain, as evidenced by impact of severe stress on gastrointestinal symptoms including abdominal pain diarrhea, conversely, influence discomfort mood. Clinical observations support notion connection, an increased prevalence inflammatory bowel disease (IBD) in patients with depression anxiety, well association changes gut microbiota neurological disorders such multiple sclerosis, Parkinson's disease, stroke Alzheimer's disease. brain communicate via complex mechanisms involving cytokines, immune cells, autonomic nerves, microbiota, which contribute to pathogenesis certain diseases. Two primary pathways mediate information exchange intestinal tract brain: signal transduction through bloodstream factors, bacterial metabolites neural pathways, neurotransmitters cytokines within nervous system interaction nerve cells beyond. In recent years, basic pathophysiology have been gradually elucidated. Beyond interaction, emerging evidence suggests extends other organs, liver lungs, intricate inter-organ communication pathways. An increasing number reports this clinical cross-organ interactions underscore potential for better understanding novel therapeutic strategies targeting inter-organs networks. Further clarification multiorgans premises transformative insights into strategies.

Language: Английский

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Neuro-immune-cancer interactions: Mechanisms and therapeutic implications for tumor modulation

Brain Behavior and Immunity Integrative, Journal Year: 2025, Volume and Issue: 10, P. 100119 - 100119

Published: April 1, 2025

Language: Английский

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TRP Channels in Cancer: Therapeutic Opportunities and Research Strategies

Pharmacological Research, Journal Year: 2024, Volume and Issue: 209, P. 107412 - 107412

Published: Sept. 19, 2024

Language: Английский

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Sensory neuroimmune interactions at the barrier

Mucosal Immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

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Immune control of brain physiology

Nature reviews. Immunology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

Language: Английский

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Decoding the Neuroimmune Axis in Colorectal Cancer: From Neural Circuitry to Therapeutic Innovation

Cytokine & Growth Factor Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Neural-activity-regulated and glia-mediated control of brain lymphatic development

Cell, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Sensory neurons on guard: roles in pathogen defense and host immunity

Current Opinion in Immunology, Journal Year: 2025, Volume and Issue: 93, P. 102541 - 102541

Published: Feb. 26, 2025

Language: Английский

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Les enképhalines produites par les lymphocytes T régulateurs modulent la douleur chez la souris

médecine/sciences, Journal Year: 2025, Volume and Issue: 41(2), P. 127 - 129

Published: Feb. 1, 2025

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