Establishment of local wastewater-based surveillance programmes in response to the spread and infection of COVID-19 – case studies from South Africa, the Netherlands, Turkey and England

Journal of Water and Health, Journal Year: 2022, Volume and Issue: 20(2), P. 287 - 299

Published: Feb. 1, 2022

The COVID-19 pandemic has resulted in over 340 million infection cases (as of 21 January 2022) and more than 5.57 deaths globally. In reaction, science, technology innovation communities across the globe have organised themselves to contribute national responses disease. A significant contribution been from establishment wastewater-based epidemiological (WBE) surveillance interventions programmes for monitoring spread at least 55 countries. Here, we examine share experiences lessons learnt establishing such programmes. We use case studies highlight testing methods logistics considerations associated scaling implementing South Africa, Netherlands, Turkey England. four countries were selected represent different regions world perspective based on considerable progress made their WBE also climatic zones, economies, development stages, which influence implementation this nature magnitude. addition, countries' offer good since they are systematic, cover extensive areas, disseminate knowledge locally internationally partnered with authorities (government). strengthened working relations partnerships between among local global organisations. This paper shares these encourage others water public health sectors benefits value tackling SARS-CoV-2 related future circumstances.

Language: Английский

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Quantifying the Relationship between SARS-CoV-2 Wastewater Concentrations and Building-Level COVID-19 Prevalence at an Isolation Residence: A Passive Sampling Approach

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(18), P. 11245 - 11245

Published: Sept. 7, 2022

SARS-CoV-2 RNA loads can be detected in the excreta of individuals with COVID-19 and have demonstrated positive correlations clinical infection trends. Consequently, wastewater-based epidemiology (WBE) approaches been implemented globally as a public health surveillance tool to monitor community-level prevalence infections. The majority wastewater specimens are gathered either composite samples via automatic samplers (autosamplers) or grab samples. However, autosamplers expensive challenging maintain cold weather, while particularly susceptible temporal variation when sampling sewage directly from complex matrices outside residential buildings. Passive provide an affordable, practical, scalable system maintaining reproducible signal. In this regard, we deployed tampons passive isolation unit (a segregated residence hall) at university campus 1 February 2021-21 May 2021. Samples (n = 64) were collected 3-5 times weekly remained within sewer for median duration 24 h. was quantified using reverse-transcription quantitative polymerase chain reaction (RT-qPCR) targeting N1 N2 gene fragments. We mean viral load captured per individual association between daily total persons, adjusting covariates multivariable models baseline estimate shedding. processed through two distinct laboratory pipelines on campus, yielding highly correlated concentrations. Data obtained here highlight success utilizing capture coming residence, indicating that method help inform building-level responses.

Language: Английский

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Wastewater Surveillance for SARS-CoV-2 RNA in Canada

FACETS, Journal Year: 2022, Volume and Issue: 7, P. 1493 - 1597

Published: Jan. 1, 2022

Wastewater surveillance for SARS-CoV-2 RNA is a relatively recent adaptation of long-standing wastewater infectious and other harmful agents. Individuals infected with COVID-19 were found to shed in their faeces. Researchers around the world confirmed that fragments could be detected quantified community wastewater. Canadian academic researchers, largely as volunteer initiatives, reported proof-of-concept by April 2020. National collaboration was initially facilitated Water Network. Many public health officials skeptical about actionable information being provided even though experience has shown pandemic no single, perfect approach. Rather, different approaches provide insights, each its own strengths limitations. Public science must triangulate among forms evidence maximize understanding what happening or may expected. Well-conceived, resourced, implemented wastewater-based platforms can cost-effective approach support conventional lines evidence. Sustaining monitoring future disease targets states challenge. Canada benefit from taking lessons learned develop forward-looking interpretive frameworks capacity implement, adapt, expand such capabilities.

Language: Английский

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Long-term passive wastewater surveillance of SARS-CoV-2 for seven university dormitories in comparison to municipal surveillance

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 852, P. 158421 - 158421

Published: Sept. 1, 2022

Language: Английский

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Passive swab versus grab sampling for detection of SARS-CoV-2 markers in wastewater

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 889, P. 164180 - 164180

Published: May 16, 2023

Language: Английский

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