General or Central Obesity and Mortality Among US Hispanic and Latino Adults DOI Creative Commons
Yanbo Zhang, Guo‐Chong Chen, Daniela Sotres‐Alvarez

et al.

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(1), P. e2351070 - e2351070

Published: Jan. 16, 2024

Importance The Hispanic and Latino population is the second largest ethnic group in US, but associations of obesity parameters with mortality this remain unclear. Objective To investigate general central among US adults. Design, Setting, Participants Community Health Study/Study Latinos an ongoing, multicenter, population-based cohort study a multistage probability sampling method performed adults aged 18 to 74 years baseline between January 1, 2008, December 31, 2011. Active follow-up for analyses extended from through February 17, 2022. All accounted complex survey design (ie, stratification clustering) weights generate estimates representing noninstitutionalized, 18- 74-year-old or populations selected communities. Exposures Body mass index (BMI; calculated as weight kilograms divided by height meters squared), body fat percentage, waist circumference (WC), hip ratio (WHR). Main Outcome Measure Deaths were ascertained via death certificates, National Death Index, active follow-up. Results Of 15 773 (mean [SE] age, 40.9 [0.3] years; 52.8% female), 686 deaths occurred during median (IQR) 10.0 (9.9-10.2) years. When adjusting sociodemographic, lifestyle, family history covariates, hazard ratios (HRs) 1.55 (95% CI, 1.08-2.22) BMI 35.0 greater vs 18.5 24.9, 1.22 0.92-1.64) highest lowest percentage groups (defined according sex-, age-, background–specific distribution), 1.35 0.98-1.85) WC than 102 cm (men) 88 (women) 94 80 less, 1.91 1.28-2.86) WHR 0.90 0.85 less (women). Only was associated additional adjustment major comorbidities (HR, 1.75; 95% 1.17-2.62). association stronger women compared men ( P = .03 interaction), .02 interaction). positive severe (BMI ≥ 35.0) observed only not those below .005 interaction) who had circumference. Conclusions Relevance In adults, independently higher all-cause regardless prevalent comorbidities. These findings suggest that prioritizing clinical screening intervention may be important public health strategy, sex-specific strategies potentially being needed.

Language: Английский

Implementing the 27 PRISMA 2020 Statement items for systematic reviews in the sport and exercise medicine, musculoskeletal rehabilitation and sports science fields: the PERSiST (implementing Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science) guidance DOI Creative Commons
Clare L. Ardern, Fionn Büttner, Renato Andrade

et al.

British Journal of Sports Medicine, Journal Year: 2021, Volume and Issue: 56(4), P. 175 - 195

Published: Oct. 8, 2021

Poor reporting of medical and healthcare systematic reviews is a problem from which the sports exercise medicine, musculoskeletal rehabilitation, science fields are not immune. Transparent, accurate comprehensive review helps researchers replicate methods, readers understand what was done why, clinicians policy-makers implement results in practice. The Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) Statement its accompanying Explanation Elaboration document provide general examples interventions. However, implementation guidance sport does exist. Prisma Exercise, Rehabilitation, Sport medicine SporTs (PERSiST) attempts to address this problem. Nineteen content experts collaborated with three methods identify exemplary (including physical activity), rehabilitation physiotherapy), science, each PRISMA 2020 items. PERSiST aims help: (1) reviewers improve transparency (2) journal editors peer make informed decisions about quality.

Language: Английский

Citations

261
Association of metabolic–bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants DOI
Nicholas Syn,

David E. Cummings,

Louis Z Wang

et al.

The Lancet, Journal Year: 2021, Volume and Issue: 397(10287), P. 1830 - 1841

Published: May 1, 2021

Language: Английский

Citations

164
Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies DOI Creative Commons
Ahmad Jayedi, Sepideh Soltani,

Sheida Motlagh

et al.

BMJ, Journal Year: 2022, Volume and Issue: unknown, P. e067516 - e067516

Published: Jan. 18, 2022

Abstract Objective To present a comprehensive review of the association between measures body weight, waist, and fat, different ratios these measures, risk type 2 diabetes. Design Systematic dose-response meta-analysis cohort studies. Data sources PubMed, Scopus, Web Science up to 1 May 2021. Review methods Cohort studies looking at general or central adiposity fat content diabetes in adult population were included. Two authors extracted data duplicate. Random effects meta-analyses performed estimate degree associations. Curvilinear associations modelled with one stage weighted mixed meta-analysis. Results 216 2.3 million individuals among 26 participants identified. Relative risks 1.72 (95% confidence interval 1.65 1.81; n=182 studies) for an increase mass index 5 units, 1.61 (1.52 1.70; n=78) 10 cm larger waist circumference, 1.63 (1.50 1.78; n=34) waist-to-hip ratio 0.1 1.73 (1.51 1.98; n=25) waist-to-height 1.42 (1.27 1.58; n=9) visceral unit, 2.05 (1.41 2.98; n=6) 10% higher percentage 1.09 (1.05 1.13, n=5) shape 0.005 2.55 (1.59 4.10, n=4) index, 1.11 (0.98 1.27; n=14) hip circumference. A strong positive linear was found Positive monotonic also all regions ethnicities, without marked deviation from linearity specific cut-off value. Indices fatness, independent overall adiposity, had total mass, although number small. Conclusions associated greater developing strongly linearly registration PROSPERO CRD42021255338.

Language: Английский

Citations

151
Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study DOI Creative Commons
Qiufen Sun, Dongmei Yu,

Junning Fan

et al.

The Lancet Public Health, Journal Year: 2022, Volume and Issue: 7(12), P. e994 - e1004

Published: Aug. 1, 2022

Language: Английский

Citations

104
Obesity in South and Southeast Asia—A new consensus on care and management DOI Creative Commons
Kwang Wei Tham, Rohana Abdul Ghani,

C. Sioksoan

et al.

Obesity Reviews, Journal Year: 2022, Volume and Issue: 24(2)

Published: Dec. 1, 2022

Obesity is a chronic disease in which the abnormal or excessive accumulation of body fat leads to impaired health and increased risk mortality complications. Prevalence obesity rising rapidly South Southeast Asia, with potentially serious consequences for local economies, healthcare systems, quality life. Our group specialists from Bangladesh, Brunei Darussalam, India, Indonesia, Malaysia, Philippines, Singapore, Sri Lanka, Thailand, Viet Nam undertook develop consensus recommendations management care adults children Asia. To this end, we identified researched 12 clinical questions related obesity. These address optimal approaches identifying staging obesity, treatment (lifestyle, behavioral, pharmacologic, surgical options) maintenance reduced weight, as well issues weight stigma patient engagement setting. We achieved on 42 that these questions. An algorithm describing presented, keyed various recommendations.

Language: Английский

Citations

86
Effects of Experimental Sleep Restriction on Energy Intake, Energy Expenditure, and Visceral Obesity DOI Creative Commons

Naima Covassin,

Prachi Singh, Shelly McCrady-Spitzer

et al.

Journal of the American College of Cardiology, Journal Year: 2022, Volume and Issue: 79(13), P. 1254 - 1265

Published: March 28, 2022

Language: Английский

Citations

71
Type 2 diabetes mellitus in adults: pathogenesis, prevention and therapy DOI Creative Commons
Xi Lu,

Qingxing Xie,

Xiaohui Pan

et al.

Signal Transduction and Targeted Therapy, Journal Year: 2024, Volume and Issue: 9(1)

Published: Oct. 2, 2024

Language: Английский

Citations

54
Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome DOI Creative Commons
Xiaoyuan Wei, Min Yu, Song Ge

et al.

Cardiovascular Diabetology, Journal Year: 2024, Volume and Issue: 23(1)

Published: April 24, 2024

Abstract Background Triglyceride-glucose (TyG) index has been determined to play a role in the onset of metabolic syndrome (MetS). Whether TyG and with combination obesity indicators are associated clinical outcomes MetS population remains unknown. Method Participants were extracted from multiple cycles National Health Nutrition Examination Survey (NHANES) between 1999 2018 years. Three constructed including index, combining waist circumference (TyG-WC), waist-to-height ratio (TyG-WHtR). The was defined according Cholesterol Education Program (NCPE) Adult Treatment Panel III. Kaplan-Meier (KM) curves, restricted cubic splines (RCS), Cox proportional hazard model used evaluate associations TyG-related indices mortality population. sensitive analyses performed check robustness main findings. Results There 10,734 participants included this study, 5,570 females 5,164 males. median age study 59 years old. multivariate regression showed high levels significantly all-cause [TyG index: adjusted (aHR): 1.36, 95%confidence interval (CI): 1.18–1.56, p < 0.001; TyG-WHtR aHR = 1.29, 95%CI: 1.13–1.47, 0.001]. Meanwhile, TyG-WC cardiovascular (TyG-WC: 1.45, 1.13–1.85, 0.004; TyG-WHtR: 1.50 1.17–1.92, 0.002). consistent significant correlations diabetes (TyG: 4.06, 2.81–5.87, TyG-WC: 2.55, 1.82–3.58, 2.53 1.81–3.54, 0.001). RCS curves non-linear trend (p for nonlinearity 0.004 0.001, respectively). supported positive Conclusion Our highlights value predicting survival would be surrogate biomarkers follow-up

Language: Английский

Citations

50
Body mass index, waist circumference, and mortality in subjects older than 80 years: a Mendelian randomization study DOI
Yuebin Lv, Yue Zhang, Xinwei Li

et al.

European Heart Journal, Journal Year: 2024, Volume and Issue: 45(24), P. 2145 - 2154

Published: April 16, 2024

Abstract Background and Aims Emerging evidence has raised an obesity paradox in observational studies of body mass index (BMI) health among the oldest-old (aged ≥80 years), as inverse relationship BMI with mortality was reported. This study to investigate causal associations BMI, waist circumference (WC), or both people China. Methods A total 5306 community-based (mean age 90.6 years) were enrolled Chinese Longitudinal Healthy Longevity Survey (CLHLS) between 1998 2018. Genetic risk scores constructed from 58 single-nucleotide polymorphisms (SNPs) associated 49 SNPs WC subsequently derive estimates for Mendelian randomization (MR) models. One-sample linear MR along non-linear analyses performed explore genetically predicted WC, their joint effect all-cause mortality, cardiovascular disease (CVD) non-CVD mortality. Results During 24 337 person-years follow-up, 3766 deaths documented. In analyses, higher decreased [hazard ratio (HR) 0.963, 95% confidence interval (CI) 0.955–0.971 a 1-kg/m2 increment HR 0.971 (95% CI 0.950–0.993) each 5 cm increase WC]. Linear models indicated that 1 kg/m2 monotonically 4.5% decrease [HR 0.955 0.928–0.983)]. Non-linear curves showed lowest at around 28.0 kg/m2, suggesting optimal may be overweight mild obesity. Positive monotonic observed 1.108 1.036–1.185) per increase], CVD 1.193 1.064–1.337)], 1.110 1.016–1.212)]. The those lower WC. Conclusions Among oldest-old, opposite observed, figure could substantially risk. Guidelines weight management should cautiously designed implemented people, considering distinct roles

Language: Английский

Citations

29
Association of triglyceride glucose-related parameters with all-cause mortality and cardiovascular disease in NAFLD patients: NHANES 1999–2018 DOI Creative Commons

Yusha Zhang,

Fengjiao Wang, Jianjun Tang

et al.

Cardiovascular Diabetology, Journal Year: 2024, Volume and Issue: 23(1)

Published: July 18, 2024

Abstract Background The relationship between the triglyceride-glucose (TyG) index and its derived index, triglyceride glucose-waist height ratio (TyG-WHtR), with mortality cardiovascular diseases (CVDs) in patients non-alcoholic fatty liver disease (NAFLD) remains unclear. Methods This study enrolled 6627 adults aged 18 above diagnosed NAFLD from National Health Nutrition Examination Survey (NHANES, 1999–2018). Binary weighted logistic regression analyses, cox proportional hazards model restricted cubic spline (RCS) were used to analyze TyG TyG-WHtR all-cause mortality, CVD CVDs. Mediation analysis explored mediating role of glycohemoglobin, insulin hypertension relationships. Meanwhile, incremental predictive value was further assessed. Results Except for no significant association both chronic heart failure (CHF), exhibited positive correlations or trends correlation total-CVD, CHF, coronary (CHD) angina pectoris. For a better predictor than (TyG-WHtR: HR 1.31, 95%CI 1.03–1.66; 2.22, 1.42–3.47; OR 3.99, 1.79–8.93). In contrast, demonstrated stronger CHD pectoris (TyG index: 2.00, 1.26–3.18; 1.85, 1.19–2.91; 2.93, 1.23-7.00). RCS showed that after adjusting covariates, most aforementioned relationships linear(P overall < 0.0001, P-nonlinear > 0.05), while associations CHF non-linear(P P nonlinear 0.05). addition basic outcomes improved C-statistics, net reclassification improvement value, integrated discrimination value. Conclusions risk significant. might be valid predictors NAFLD.

Language: Английский

Citations

29