Antioxidant Properties of Zinc and Copper—Blood Zinc-to Copper-Ratio as a Marker of Cancer Risk BRCA1 Mutation Carriers
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(7), P. 841 - 841
Published: July 14, 2024
Pathogenic
mutations
in
BRCA1
(BReast
CAncer
gene
1)
confer
high
risks
of
both
breast
(up
to
70%)
and
ovarian
40%)
cancers.
Zinc
(Zn)
copper
(Cu)
are
essential
for
various
physiological
functions,
including
antioxidant
reactions.
Their
balance,
reflected
the
Zn/Cu
ratio,
plays
a
crucial
role
maintaining
redox
homeostasis,
which
is
vital
cancer
prevention.
This
study
examines
properties
Zn
Cu,
specifically
focusing
on
blood
ratio
as
potential
marker
risk
among
mutation
carriers.
The
cohort
consisted
989
initially
unaffected
women,
followed
up
7.5
years.
Blood
samples
were
analyzed
using
inductively
coupled
plasma
mass
spectrometry.
Although
individual
Cu
levels
did
not
significantly
correlate
with
overall
risk,
those
women
above
6.38
experienced
lower
than
below
this
cut-off
point.
suggests
that
may
be
valuable
biomarker
prevention
high-risk
group.
Given
increased
carriers,
optimizing
through
dietary
active
interventions
could
provide
preventive
strategy.
Language: Английский
Mediterranean diet protects against a neuroinflammatory cortical transcriptome: Associations with brain volumetrics, peripheral inflammation, social isolation, and anxiety in nonhuman primates (Macaca fascicularis)
Brain Behavior and Immunity,
Journal Year:
2024,
Volume and Issue:
119, P. 681 - 692
Published: April 16, 2024
Language: Английский
Leveraging plate for health: How food carves our immunity
Jinhui Jia,
No information about this author
Jiahui Li,
No information about this author
Jian Guo
No information about this author
et al.
Trends in Food Science & Technology,
Journal Year:
2025,
Volume and Issue:
156, P. 104865 - 104865
Published: Jan. 2, 2025
Language: Английский
The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis
Frontiers in Nutrition,
Journal Year:
2025,
Volume and Issue:
12
Published: May 9, 2025
Introduction
The
pandemic
crisis
is
now
a
memorable
milestone
in
the
history
of
science,
not
only
for
impacts
on
population’s
health
but
also
effort
medical
community
to
find
immediate
solutions
amid
so
that
appropriate
therapeutic
means
can
be
provided.
Diet
and
nutrition
could
fail
studied
context
combating
side
effects
COVID-19.
This
study
attempts
detect
relationship
between
dietary
patterns
disease
COVID-19
emphasizes
research
probiotics
by
mapping
knowledge
produced
during
until
2024.
Methods
In
addition
bibliometrics,
machine-learning
framework,
ASReview,
was
used
structure
literature
search.
With
this
method,
2,309
articles
were
collected
from
PubMed
database,
with
599
constituting
inputs
into
bibliometric
software
further
analysis.
Results
Food
choices,
patterns,
vitamins
their
role
(vitamin
D),
obesity,
keywords
attracted
global
attention.
Dietary
supplements
constituted
field
regarding
evolution
impact
they
have
after
first
wave.
Discussion
Probiotics
considered
an
adjunct
intervention
period
before
development
vaccines
alongside
other
solutions.
Whether
preventively
or
treatment
phase,
combat
due
potential
immunomodulation
ability
regulate
gut
microbiota
respiratory
infections.
Language: Английский
Unveiling the Path to Resilience: Prioritizing Mental Health, Sleep, and Nutrition in the Post-COVID Era
Healthcare,
Journal Year:
2023,
Volume and Issue:
11(17), P. 2463 - 2463
Published: Sept. 4, 2023
The
COVID-19
pandemic
has
disrupted
daily
life,
impacting
relationships,
work,
and
education.
This
led
to
increased
stress,
anxiety,
depression,
along
with
altered
sleep
patterns
eating
behaviors.
Quarantine
isolation
have
worsened
mental
health,
especially
in
children
the
elderly,
due
loss
of
activities
physical
contact.
Sleep
disorders
negative
dreams
perpetuate
poor
quality,
increasing
risk
health
issues.
Sedentary
lifestyles
emotional
effects
contribute
unhealthy
obesity,
exacerbated
by
routines
limited
outdoor
activities.
Addressing
these
challenges
requires
prioritizing
promoting
healthy
habits,
addressing
obesity
factors.
profoundly
affected
human
well-being,
but
resilience,
sleep,
nutrition
can
enhance
overall
well-being
adaptability
post-COVID
era.
comprehensive
opinion
aims
raise
awareness
wide-ranging
impacts
this
on
various
aspects
emphasize
importance
implementing
strategies
that
prioritize
improve
address
behaviors,
foster
resilience
navigate
thrive
face
future
challenges.
Language: Английский
Review Article on Molecular Basis of Zinc and Copper Interactions in Cancer Physiology
Biological Trace Element Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 31, 2024
Language: Английский
Mediterranean Diet Protects Against a Neuroinflammatory Cortical Transcriptome: Associations with Brain Volumetrics, Peripheral Inflammation, Social Isolation and Anxiety
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Nov. 3, 2023
Abstract
INTRODUCTION
Mediterranean
diets
may
be
neuroprotective
and
prevent
cognitive
decline
relative
to
Western
diets,
however
the
underlying
biology
is
poorly
understood.
METHODS
We
assessed
effects
of
vs.
Mediterranean-like
on
RNAseq
generated
transcriptional
profiles
in
temporal
cortex
their
relationships
with
changes
MRI
neuroimaging
phenotypes,
circulating
monocyte
gene
expression,
observations
social
isolation
anxiety
38
socially-housed,
middle-aged
female
cynomolgus
macaques.
RESULTS
Diet
resulted
differential
expression
seven
transcripts
(FDR<0.05).
Cyclin
dependent
kinase
14
(
CDK14
),
a
proinflammatory
regulator,
was
lower
group.
The
remaining
six
[i.e.,
“lunatic
fringe”
LFNG
mannose
receptor
C
type
2
MRC2
solute
carrier
family
3
member
SLCA32
butyrophilin
subfamily
A1
BTN2A1
katanin
regulatory
subunit
B1
KATNB1
transmembrane
protein
268
TMEM268
)]
were
higher
group
generally
associated
anti-inflammatory/neuroprotective
pathways.
encodes
subcomponent
katanin,
important
maintaining
microtubule
homeostasis.
involved
immunomodulation
γδ
T-cells
which
have
anti-neuroinflammatory
effects.
,
MRC2,
are
inflammatory
latter
four
differentially
expressed
transcript
levels,
AD-relevant
brain
volumes
determined
by
over
course
study,
anxiety.
positively
correlated
transcripts,
total
brain,
gray
matter,
cortical
matter
volumes,
time
alone
anxious
behavior,
negatively
white
cerebrospinal
fluid
(CSF)
volumes.
In
contrast,
volume,
CSF
volume
changes,
alone.
DISCUSSION
Collectively,
our
results
suggest
that
confer
protection
against
peripheral
central
inflammation
reflected
preserved
structure
behavior.
Language: Английский
Letter to the editor: Efficacy of probiotic treatment as postexposure prophylaxis for COVID-19: A double-blind, PlaceboControlled randomized trial
Yuan Ji,
No information about this author
Jinhan Chen,
No information about this author
Yuying Chi
No information about this author
et al.
Clinical Nutrition,
Journal Year:
2024,
Volume and Issue:
43(6), P. 1501 - 1502
Published: May 7, 2024
Language: Английский
Diet enrichment with omega-3 fatty acids: effect on productive performance, egg quality traits, yolk fatty acid profiles, oxidative stability, blood biochemistry and immune system
Seyed Davood Sharifi,
No information about this author
Mahdi Abedini Sanij,
No information about this author
Hasan Rouhanipour
No information about this author
et al.
Acta Agriculturae Scandinavica Section A – Animal Science,
Journal Year:
2024,
Volume and Issue:
73(3-4), P. 117 - 129
Published: May 31, 2024
The
objective
of
this
study
was
to
examine
the
effects
enriching
diet
with
Omega-3
fatty
acids
on
productive
performance,
yolk
acid
profiles,
oxidative
stability,
blood
biochemistry,
and
immune
system
laying
hens.
Enriching
improved
egg
production
FCR
(P
<
0.05).
Docosahexaenoic
(DHA)
total
omega-3
in
increased
linearly
Salomega
level
Serum
cholesterol
triglyceride
decreased,
but
HDL
content
parallel
MDA
bird
eggs
3
or
4%
treatment
higher
than
control
group
In
conclusion,
enrichment
hens'
salomega
can
enhance
production,
elevate
levels
acids,
decrease
stability
lipids.
Language: Английский
Association between cardiovascular health and pelvic inflammatory disease: Analyses of the NHANES 2015 to 2018
Medicine,
Journal Year:
2024,
Volume and Issue:
103(29), P. e38981 - e38981
Published: July 19, 2024
While
the
link
between
female
reproductive
function
and
cardiovascular
health
(CVH)
is
well-established,
association
pelvic
inflammatory
disease
(PID)
CVH
remains
largely
unexplored.
This
study,
therefore,
sets
out
to
fill
this
gap
in
knowledge
by
investigating
potential
relationship
PID
CVH.
To
ensure
reliability
validity
of
our
findings,
data
for
cross-sectional
study
were
meticulously
collected
from
2015–2018
National
Health
Nutrition
Examination
Survey
(NHANES).
After
applying
stringent
exclusion
criteria,
a
total
2442
women
included
study.
The
Life
Essential
8
(LE8)
scoring
system,
robust
tool
developed
American
Heart
Association
(AHA),
was
employed
assess
Logistic
regression
with
multiple
variables
smooth
curve
fitting
utilized
analyze
association.
Subgroup
interaction
analyses
performed
determine
strength
across
different
demographic
groups.
women,
an
average
score
66.29
±
16.27.
accounting
all
covariates,
each
unit
increase
associated
2%
lower
odds
prevalence
(OR
=
0.98,
95%
CI:
0.97–0.99).
Notably,
participants
high
had
striking
71%
compared
those
low
Stratified
further
revealed
consistent
inverse
various
subgroups,
underscoring
robustness
findings.
research
has
uncovered
significant
PID.
suggests
that
improving
level
could
be
promising
strategy
reducing
Language: Английский