Nutraceutical blends predict enhanced health via microbiota reshaping improving cytokines and life quality: a Brazilian double-blind randomized trial

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: May 15, 2024

Abstract Nutraceutical interventions supporting microbiota and eliciting clinical improvements in metabolic diseases have grown significantly. Chronic stress, gut dysbiosis, metainflammation emerged as key factors intertwined with sleep disorders, consequently exacerbating the decline quality of life. This study aimed to assess effects two nutraceutical formulations containing prebiotics (fructooligosaccharides (FOS), galactooligosaccharides (GOS), yeast β-glucans), minerals (Mg, Se, Zn), herbal medicine Silybum marianum L. Gaertn., Asteraceae (Milk thistle or Silymarin). These formulations, namely NSupple (without silymarin) NSupple_ (with were tested over 180 days overweight/obese volunteers from Brazil's southeastern region. We accessed fecal by partial 16S rRNA sequences; cytokines expression CBA; anthropometrics, life sleep, well hormonal parameters, at baseline (T0) (T180) post-supplementation. Results demonstrated reshaping phyla, genera, species level The Bacteroidetes phylum, Bacteroides , Prevotella genera positively modulated especially group. Gut modulation was associated improved patterns, quality-of-life perception, expression, anthropometric parameters Our findings suggest that blends enhance cardiometabolic inflammatory markers. Particularly, composition, underscoring its potential significance ameliorating dysregulation. Clinical trial registry number: NCT04810572. 23/03/2021.

Language: Английский

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Adherence to the Mediterranean Diet and Its Association With Sleep Quality and Chronotype Among Youth: A Cross-Sectional Study

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 8

Published: Jan. 19, 2022

Background Evidence indicates that many university students have poor adherence to a healthy diet accompanied by unhealthy lifestyle behaviors. Chrono-nutrition is an emerging field of research examines the pattern optimum daily activity in relation human's dietary patterns, and their reflections variable health indicators such as sleep quality. However, there scarcity relationship between eating pattern, like Mediterranean (MD), with quality chronotype among students. Methods A cross-sectional study was conducted, convenience sampling used. Participants were assessed for MD using Diet Quality Index (KIDMED), Pittsburgh Sleep (PSQI), Morningness-Eveningness questionnaire (MEQ). Results The included 503 students, most them (81.5%) females. Only 15.1 16.9% reported morningness good quality, respectively. About half showed medium high KIMED. In-depth analysis revealed more likely (OR = 0.35; 95%CI: 0.21–0.59; P < 0.001) even after adjustment age sex 0.36; 0.21–0.62; 0.001). regression also those had significant association better subjective less latency, disturbance, daytime dysfunction sex. Those about six-fold higher chance 5.67; 2.86–11.26; 0.001, respectively). Conclusions Good presented associated improved overall components. Long-term, controlled intervention works are warranted elaboration on impact habits other important aspects mental academic achievement.

Language: Английский

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The emerging importance of tackling sleep–diet interactions in lifestyle interventions for weight management

British Journal Of Nutrition, Journal Year: 2022, Volume and Issue: 128(3), P. 561 - 568

Published: May 23, 2022

Abstract Sleep habits are directly related to risk of obesity, and this relationship may be partly mediated through food choices eating behaviour. Short sleep duration, impaired quality suboptimal timing all implicated in weight gain adverse cardiometabolic health, at least their associations with diet quality. Short-term restriction leads increased energy intake, habitually short sleepers report dietary intakes that indicate a less healthy compared adequate sleepers. Evidence is emerging extension interventions reduce intake sugars overall intake. Poor quality, night shift work patterns social jetlag also associated lower consumption energy-dense foods. Incorporating advice into management more effective than energy-restricted diets exercise alone. However, there lack intervention studies aim lengthen sleep, improve or adjust irregular investigate the impact on behaviour participants aiming lose maintain loss. Finally, future research should take account individual characteristics such as age, sex, life stage changing working practices when designing combined lifestyle including change for health well-being.

Language: Английский

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Effects of lifestyle factors on leukocytes in cardiovascular health and disease

Nature Reviews Cardiology, Journal Year: 2023, Volume and Issue: 21(3), P. 157 - 169

Published: Sept. 26, 2023

Language: Английский

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Food Intake and Sleep Disorders in Children and Adolescents with Obesity

Nutrients, Journal Year: 2023, Volume and Issue: 15(22), P. 4736 - 4736

Published: Nov. 9, 2023

Over the last few decades, numerous scientific studies have investigated possible association between sleep duration and adiposity during childhood, since it has been reported that deprivation causes a related increase in caloric intake. Even though underlying pathogenetic mechanisms are still under study not completely known, effect of dietetic habits nutrient intake on quality patterns reported. The aim this is to explore intricate interplay food intake/diet pediatric disturbances children adolescents with obesity, emphasizing importance underestimating aspect prevention treatment complex disease. Recent evidence supports high correlation specific diet foods at all ages. Diets rich fiber, fruit, vegetables, anti-inflammatory nutrients low saturated fats seem promote better quality. Sleep are, turn, risk factors for development obesity. Therefore, strategies should be applied counteract harmful process. Unraveling links dietary habits, patterns, obesity essential developing effective combat critical public health issue.

Language: Английский

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Dietary fiber: Still alive

Food Chemistry, Journal Year: 2023, Volume and Issue: 439, P. 138076 - 138076

Published: Nov. 28, 2023

Dietary fiber (DF) was established as a key dietary constituent some decades ago, were of its mechanisms action and health effects. Although there is consolidated evidence on many features regarding DF, at the same time are still aspects to be explored in field, e.g., deeper explorations contribution phenolic compounds linked cell walls biological activities or relevance gut-brain axis. At time, increasing DF intake should seen major public problem since worldwide intakes quite far from recommendations. The awareness this fact by bodies lead, among others, assessment effective strategies for promoting general population specific groups; consider potential regulatory modifications order clarify several potentially misleading consumers.

Language: Английский

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Mediterranean Dietary Patterns Related to Sleep Duration and Sleep-Related Problems among Adolescents: The EHDLA Study

Nutrients, Journal Year: 2023, Volume and Issue: 15(3), P. 665 - 665

Published: Jan. 28, 2023

The aim of the present study was to examine association adherence Mediterranean Diet (MD) and its specific components with both sleep duration sleep-related disorders in a sample adolescents from Valle de Ricote (Region Murcia, Spain).This cross-sectional included 847 Spanish (55.3% girls) aged 12-17 years. Adherence MD assessed by Quality Index for Children Teenagers. Sleep reported weekdays weekend days separately. BEARS (Bedtime problems, Excessive daytime sleepiness, Awakenings during night, Regularity sleep, Sleep-disordered breathing) screening used evaluate issues related which include difficulties at bedtime, excessive drowsiness day, waking up frequently irregularity, length breathing while sleeping.Adolescents who presented high were more likely meet recommendations (OR = 1.52, 95% CI 1.12-2.06, p 0.008) less report least one problem 0.56, 0.43-0.72, < 0.001). These findings remained significant after adjusting sex, age, socioeconomic status, waist circumference, energy intake, physical activity, sedentary behavior, indicating outcomes (meeting recommendations: OR 1.40, 1.00-1.96, 0.050; problems: 0.68, 0.50-0.92, 0.012).Adolescents optimal fewer problems. This clearly observed components, such as fruits, pulses, fish, having breakfast, dairies, sweets, baked goods/pastries.

Language: Английский

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Relation between dietary inflammatory potential and sleep features: Systematic review of observational studies

Mediterranean Journal of Nutrition and Metabolism, Journal Year: 2024, Volume and Issue: 17(1), P. 1 - 14

Published: Feb. 27, 2024

BACKGROUND: Diet and sleep represent key behavioral risk factors for major non-communicable diseases. Dietary may modulate systemic inflammation potentially affect the human brain functionality, finally affecting sleep-wake cycle. In this context, Inflammatory Index (DII) has been studied as a tool to investigate dietary inflammatory potential its relationship with variety of health conditions. OBJECTIVE: The aim study was perform systematic revision observational studies on diet assessed through DII features. METHODS: A search features conducted Pubmed EMBASE electronic databases. Meta-analyses Of Observational Studies in Epidemiology (MOOSE) guidelines were used plan methodology. identified selected according inclusion/exclusion criteria. RESULTS: review led selection 13 studies. Most including general population reported an association between higher worse quality suboptimal duration. Some also daytime sleepiness apnea. However, some younger individuals (i.e., college students or young employees) null findings. Four conditions showed relation features, although results not fully consistent. CONCLUSIONS: Data published so far suggests lack randomized clinical trials better designed studies, imply that further research matter is warranted understand whether causal could explain current

Language: Английский

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The Association Between Ultra-Processed Food Consumption and Chronic Insomnia in the NutriNet-Santé Study

Journal of the Academy of Nutrition and Dietetics, Journal Year: 2024, Volume and Issue: 124(9), P. 1109 - 1117.e2

Published: Feb. 28, 2024

The consumption of ultra-processed foods (UPF) is on the rise worldwide, and it has been linked to numerous health conditions, such as diabetes, obesity, cancer. Few studies have focused effect UPF sleep even fewer chronic insomnia. This study investigated association between intake insomnia in a large population-based sample. was cross-sectional analysis using NutriNet-Santé data, an ongoing Web cohort France. Thirty-eight thousand five hundred seventy adult males females who had completed questionnaire (2014) at least two 24-hour dietary records were included analysis. Chronic defined according established criteria. Categorization food beverages based NOVA-Group 4 classification. assessed multivariable logistic regression. Among 38,570 participants (mean age, 50.0 ±14.8 years, 77.0% female) analysis, 19.4% symptoms On average, represented 16% total amount (g/day) overall intake. In fully adjusted model, associated with higher odds (odds ratio [OR] for absolute 10% greater diet = 1.06; 95% confidence interval [CI]: 1.02-1.09). Sex-specific OR 1.09 (1.01-1.18) among 1.05 (1.01-1.09) females. epidemiological revealed statistically significant insomnia, independent sociodemographic, lifestyle, quality, mental status covariates. findings provide insights future longitudinal research well nutrition- sleep-focused intervention prevention programs.

Language: Английский

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Chrono-nutrition and sleep - lessons from the temporal feature of eating patterns in human studies: A systematic scoping review

Sleep Medicine Reviews, Journal Year: 2024, Volume and Issue: 76, P. 101953 - 101953

Published: May 18, 2024

An emerging field of research has revealed a bidirectional relationship between sleep and diet, highlighting the potential role healthy diet in improving sleep. However, impact chrono-nutrition on remains less explored. Here we conducted systematic scoping review, considering multiple dimensions chrono-nutrition, to describe extent, range, nature existing literature this area (PROSPERO: CRD42021274637). There been significant increase exploring topic over past six years (almost 67 % evolving literature). A breakdown included studies was performed according three major chrono-nutritional dimensions: meal timing [n = 35], irregular eating patterns 84], frequency occasions 3]. Meal sub-dimensions: breakfast skipping 13], late 16], earlier vs later meals schedules 6]. Irregular diurnal fasting 65], intermittent daily Frequency least studied dimension (n 3). We provided synthetic illustrative framework underlining important preliminary evidence linking temporal characteristics various facets health. Nonetheless, much work be done provide guidelines improve health general population.

Language: Английский

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