IEEE Access,
Journal Year:
2023,
Volume and Issue:
11, P. 119254 - 119269
Published: Jan. 1, 2023
Identifying
the
clinical
needs
to
evaluate
and
manage
treatment
monitoring
of
cancer
patients
is
a
multidimensional
challenge
in
healthcare
institutions.
In
this
regard,
electronic
health
records
(EHRs)
are
beneficial
for
managing
information;
however,
EHRs
focused
exclusively
on
with
have
not
been
sufficiently
adopted.
Chile,
need
oncology
EHR
has
only
briefly
addressed,
resulting
insufficient
updated
systematized
information
patients.
paper,
we
propose
design
an
that
manages
critical
variables
processes
Chile.
We
used
systematic
methodology
software
architecture
oriented
focus
groups
interviews
elicit
requirements
stakeholders.We
created
described
considers
four
modules
group
main
treating
Enabling
designing
registry
Chile
essential
because
it
allows
evaluation
strategic
decisions
favor
American Journal of Cancer Research,
Journal Year:
2024,
Volume and Issue:
14(6), P. 2714 - 2730
Published: Jan. 1, 2024
Image-guided
thermal
ablation
(IGTA)
is
an
important
treatment
modality
for
interventional
oncology.
It
widely
used
the
of
solid
tumors,
such
as
liver,
lung,
breast,
kidney,
and
thyroid
cancers.
IGTA
include
radiofrequency
ablation,
microwave
(MWA),
cryoablation,
laser
ablation.
Compared
with
other
energy
sources,
MWA
has
advantage
a
large
ablative
volume,
short
time,
low
heat
sink
effect.
can
also
induce
antitumor
immunity;
however,
only
minority
patients
derive
clinical
benefit
from
it.
Based
on
these
data,
combination
immunotherapy
emerged
promising
new
direction
cancer
treatment.
This
review
article
focuses
current
research
immunotherapy.
The
status
immune
activation
related
studies
involving
various
malignant
tumors
are
discussed.
Insights into Imaging,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Jan. 17, 2024
Abstract
At
the
European
Society
of
Radiology
(ESR),
we
strive
to
provide
evidence
for
radiological
practices
that
improve
patient
outcomes
and
have
a
societal
impact.
Successful
translation
research
into
clinical
practice
requires
multiple
factors
including
tailored
methodology,
multidisciplinary
approach
aiming
beyond
technical
validation,
focus
on
unmet
needs.
Low
levels
are
threat
radiology,
resulting
in
low
visibility
credibility.
Here,
background
rationale
thematic
series
Translating
practice—from
discovery
impact
,
inviting
authors
describe
their
processes
achieving
clinically
impactful
research.
We
challenges
unique
Additionally,
survey
was
sent
non-radiological
societies.
The
majority
respondents
(6/11)
were
field
gastrointestinal/abdominal
medicine.
implementation
CT/MRI
techniques
disease
characterisation,
detection
staging
cancer,
treatment
planning
interventions
mentioned
as
most
important
developments
past
years.
perception
patients
substantially
unaware
these
developments.
Unmet
needs
mostly
early
diagnosis
microstructural/functional
assessment
tissues
organs,
implant
assessment.
All
but
one
respondent
considered
radiology
discipline,
five
indicated
is
currently
not
involved
holds
potential
being
transformative
medical
practice.
It
our
responsibility
take
lead
studies
towards
highest
evidence.
Critical
relevance
statement
For
make
impact,
radiologists
should
studies,
go
feasibility
diagnostic
accuracy,
and—in
approach—address
Key
points
•
Multiple
essential
Radiological
accuracy
address
Radiologists
with
approach.
Graphical
Journal of Cancer Research and Therapeutics,
Journal Year:
2024,
Volume and Issue:
20(2), P. 531 - 539
Published: April 1, 2024
ABSTRACT
This
literature
explores
the
immunostimulatory
effects
of
thermal
ablation
in
tumor
microenvironment,
elucidating
mechanisms
such
as
immunogenic
cell
death,
tumor-specific
antigens,
and
damage-associated
molecular
patterns.
Furthermore,
it
outlines
critical
issues
associated
with
ablation-induced
challenges
offers
insights
into
future
research
avenues
potential
therapeutic
strategies.
Diagnostics,
Journal Year:
2024,
Volume and Issue:
14(7), P. 772 - 772
Published: April 5, 2024
Colorectal
cancer
is
a
leading
cause
of
cancer-related
death.
Liver
metastases
will
develop
in
over
one-third
patients
with
colorectal
and
are
major
morbidity
mortality.
Even
though
surgical
resection
has
been
considered
the
mainstay
treatment,
only
approximately
20%
candidates.
Liver-directed
locoregional
therapies
such
as
thermal
ablation,
Yttrium-90
transarterial
radioembolization,
stereotactic
body
radiation
therapy
pivotal
managing
liver
metastatic
disease.
Comprehensive
pre-
post-intervention
imaging,
encompassing
both
anatomic
metabolic
assessments,
invaluable
for
precise
treatment
planning,
staging,
response
assessment,
prompt
identification
local
or
distant
tumor
progression.
This
review
outlines
value
imaging
disease
offers
insights
into
follow-up
after
liver-directed
therapy.
Cancer Immunology Immunotherapy,
Journal Year:
2025,
Volume and Issue:
74(5)
Published: March 25, 2025
Microwave
ablation
(MWA)
is
a
super
minimally
invasive
therapeutic
approach
that
has
been
widely
applied
in
the
treatment
of
non-small
cell
lung
cancer
(NSCLC).
Although
MWA
can
elicit
antitumor
immune
responses,
these
responses
are
not
relatively
steady
and
insufficient
to
completely
clear
recurrence
tumor
cells
within
body.
Immunotherapy
monotherapy
shown
low
clinical
efficacy
advanced
NSCLC.
combined
with
checkpoint
inhibitors
(ICIs)
promising
approach.
However,
mechanism
synergic
effect
remains
elusive.
In
this
study,
we
have
conducted
retrospective
analysis
outcomes
ICIs,
finding
combinational
therapy
yielded
superior
Objective
Response
Rate
longer
Progression-Free
Survival.
preclinical
models,
established
rechallenged
model
address
post-MWA
delve
into
underlying
mechanisms
therapy.
We
observed
(MWA
+
PD-L1
blockade
therapy)
effectively
addressed
issue
model.
The
increased
function
percentage
CD8+
tumor-infiltrating
lymphocytes,
enhanced
functionality
T
tumor-draining
lymph
nodes
(TdLNs),
elevated
proportion
central
memory
cells.
Additionally,
treatments
promoted
Migration
Dendritic
Cells
type
1
(Mig
DC1)
TdLNs,
thereby
enhancing
their
activation
potential.
Notably,
FTY720-mediated
lymphocyte
egress
abolished
benefits,
confirming
TdLNs-dependent
systemic
immunity.
Moreover,
depended
on
migration
from
TdLNs
site.
summary,
proposed
potentially
effective
regimen
elucidated
cellular
underpin
its
efficacy.
