Mpox Virus in Pregnancy, the Placenta, and Newborn DOI Open Access
David A. Schwartz,

Sandy Ha,

Pradip Dashraath

et al.

Archives of Pathology & Laboratory Medicine, Journal Year: 2023, Volume and Issue: 147(7), P. 746 - 757

Published: March 1, 2023

Context.— Before its eradication, the smallpox virus was a significant cause of poor obstetric outcomes, including maternal and fetal morbidity mortality. The mpox (monkeypox) is now most pathogenic member Orthopoxvirus genus infecting humans. 2022 global outbreak has focused attention on potential effects during pregnancy. Objective.— To understand comparative different poxvirus infections pregnancy, virus, variola vaccinia cowpox virus. impact pregnant individual, fetus, placenta will be examined, with particular to occurrence intrauterine vertical transmission congenital infection. Data Sources.— data are obtained from authors' cases various published sources, early historical information contemporary publications. Conclusions.— Smallpox caused perinatal death, numerous reported transmission. In endemic African countries, also affected individuals, up 75% case fatality rate. Since start outbreak, increasing numbers women have been infected A detailed description given syndrome in stillborn resulting maternal-fetal placental infection, mechanisms infection discussed. Other poxviruses, notably and, 1 case, can Based evidence infections, remains threat population, it expected that additional occur future.

Language: Английский

COVID-19 and cause of pregnancy loss during the pandemic: A systematic review DOI Creative Commons
Seyyedeh Neda Kazemi, Bahareh Hajikhani, Hamidreza Didar

et al.

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(8), P. e0255994 - e0255994

Published: Aug. 11, 2021

Introduction The association between Coronavirus Disease 2019 (COVID-19) and abortion has been debated since the beginning of COVID-19 pandemic. We aimed to conduct this systematic review understand better potential effects Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) on fetal loss in infected mothers presented with following infection. Methods included articles published PubMed/Medline, Web Science, clinicaltrials.gov, Embase databases 2020 through a comprehensive search via appropriate keywords, including synonyms. All studies data confirmed pregnant females were collected. Results Out 208 potentially relevant articles, 11 eligible include review. reports because reasons: (1) First-trimester miscarriage; (2) Late (3) complication infection pregnancy; (4) disease artificial pregnancy. was found 5 studies, second-trimester 7 studies. Two patients acquired during hospital stay while they referred for abortion. Reports related show that most miscarriages due first trimester placental insufficiency. Conclusions There is an increased risk positive test result SARS-CoV-2, which several case series have identified Placental inflammation viral may growth retardation induce not any consistent evidence vertical transmission virus from mother fetus, requires further investigation.

Language: Английский

Citations

70
Prenatal telemedicine during COVID-19: patterns of use and barriers to access DOI Creative Commons
Alexandra Morgan, Daisy Goodman,

Julia Vinagolu-Baur

et al.

JAMIA Open, Journal Year: 2022, Volume and Issue: 5(1)

Published: Jan. 7, 2022

To evaluate patient experience with a prenatal telemedicine visit and identify barriers to accessing among rural pregnant people in northern New England during the beginning of COVID-19 pandemic.We conducted postvisit electronic survey who successfully participated at academic medical center Northern England. Nineteen questions were included 5 domains: (1) engagement care; (2) person healthcare; (3) (4) remote pregnancy surveillance tools; (5) sources information.Responses obtained from 164 people. Forty percent participants had an audio-only visit, 60% video visit. The was easy or somewhat for 79% respondents difficult 6.8%. most common barrier poor internet phone connectivity, followed by childcare responsibilities, lack equipment, privacy. Participants also engaged additional care including calls registered nurses (7.6%), communication obstetrics team through secure health messaging portal (21.1%), home monitoring (76.3%).In this survey, evaluating participating pandemic, positive overall, but identified significant participation issues connectivity equipment Most used combination other tools self-care.

Language: Английский

Citations

67
Pregnancy as a risk factor for severe coronavirus disease 2019 using standardized clinical criteria DOI Open Access
Megan C. Oakes, Annessa Kernberg, Ebony B. Carter

et al.

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2021, Volume and Issue: 3(3), P. 100319 - 100319

Published: Jan. 22, 2021

Language: Английский

Citations

65
Fear of COVID-19, mental health, and pregnancy outcomes in the pregnancy during the COVID-19 pandemic study DOI
Gerald F. Giesbrecht, Laura Rojas,

Sneha Patel

et al.

Journal of Affective Disorders, Journal Year: 2021, Volume and Issue: 299, P. 483 - 491

Published: Dec. 21, 2021

Language: Английский

Citations

64
Effects of prenatal exposure to maternal COVID-19 and perinatal care on neonatal outcome: results from the INTERCOVID Multinational Cohort Study DOI Open Access
Francesca Giuliani, D. Orós, Robert B. Gunier

et al.

American Journal of Obstetrics and Gynecology, Journal Year: 2022, Volume and Issue: 227(3), P. 488.e1 - 488.e17

Published: April 19, 2022

Language: Английский

Citations

61
Safety & effectiveness of COVID-19 vaccines: A narrative review DOI Open Access
Francesco Chirico, Jaime A. Teixeira da Silva, Panagiotis Tsigaris

et al.

The Indian Journal of Medical Research, Journal Year: 2022, Volume and Issue: 155(1), P. 91 - 104

Published: Jan. 1, 2022

There are currently eight vaccines against SARS-CoV-2 that have received Emergency Use Authorization by the WHO can offer some protection to world's population during COVID-19 pandemic. Though research is being published all over world, public health officials, policymakers and governments collecting evidence-based information establish policies. Unfortunately, continued international travel, violations of lockdowns social distancing, lack mask use, emergence mutant strains virus lower adherence a sector global remains sceptical offered vaccines, or about any risks associated with hamper these efforts. Here we examine literature on efficacy, effectiveness safety an emphasis select categories individuals new strains. The shows highly effective in protecting from severe disease death, but there issues concerning adverse effects. Further, booster shots variant-specific would also be required.

Language: Английский

Citations

59
Incidence of gestational diabetes mellitus before and after the Covid‐19 lockdown: A retrospective cohort study DOI Creative Commons
Marco La Verde, Marco Torella, Gaetano Riemma

et al.

Journal of Obstetrics and Gynaecology Research, Journal Year: 2022, Volume and Issue: 48(5), P. 1126 - 1131

Published: Feb. 23, 2022

To evaluate whether the first Covid-19 lockdown for Italian citizens (March to July 2021) might have altered incidence of gestational diabetes mellitus (GDM).A retrospective single-center study in a tertiary referral center. Primary outcome was GDM among pregnant women. incidence, from June 11, 2019 December 4, 2020, compared by dividing time as follows: beginning before (from 2019, March 9, 2020) and period 10, 2020). diagnosed with 75-g, 2-h oral glucose tolerance test (OGTT) at 24-28 weeks.Concerning 1295 women, increased during (9.3% vs. 3.4%, p < 0.001). Higher pregnancy weight gain an body mass index (BMI) delivery reported (31.3 28.4 kg/m2 , = 0.02 mean 9.3 6.6 kg, 0.007). There no difference other comorbidity OGTT values between two groups.Pregnant women experienced higher BMI diagnoses. This may be related physical limitations emotional distress lockdown. However, evidence is limited due restricted duration random variations outcomes across time. More studies are needed understand dietary patterns activity changes its impact on fetal outcomes.

Language: Английский

Citations

49
COVID‐19: A systematic review and update on prevention, diagnosis, and treatment DOI
Hooman Aghamirza Moghim Aliabadi,

Reza Eivazzadeh‐Keihan,

Arezoo Beig Parikhani

et al.

MedComm, Journal Year: 2022, Volume and Issue: 3(1)

Published: Feb. 17, 2022

Abstract Since the rapid onset of COVID‐19 or SARS‐CoV‐2 pandemic in world 2019, extensive studies have been conducted to unveil behavior and emission pattern virus order determine best ways diagnosis thereof formulate effective drugs vaccines combat disease. The emergence novel diagnostic therapeutic techniques considering multiplicity reports from one side contradictions assessments other necessitates instantaneous updates on progress clinical investigations. There is also growing public anxiety time mutation COVID‐19, as reflected considerable mortality transmission, respectively, delta Omicron variants. We comprehensively review summarize different aspects prevention, diagnosis, treatment COVID‐19. First, biological characteristics were explained standpoint. Thereafter, preclinical animal models discussed frame symptoms effects patient with strategies in‐silico/computational biology. Finally, opportunities challenges nanoscience/nanotechnology identification, discussed. This covers almost all SARS‐CoV‐2‐related topics extensively deepen understanding latest achievements (last updated January 11, 2022).

Language: Английский

Citations

44
Serum 25(OH) Vitamin D Levels in Pregnant Women with Coronavirus Disease 2019 (COVID-19): A Case-Control Study DOI Open Access
Nazaret Ferrer-Sánchez,

Marina Díaz-Goicoechea,

Victoria Mayoral-Cesar

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(7), P. 3965 - 3965

Published: March 26, 2022

The physiological changes during pregnancy may increase the risk of complications in pregnant women with coronavirus disease 2019 (COVID-19). Vitamin D is a fat-soluble secosteroid hormone and its role immunity appears to be particular importance this recent pandemic. Nevertheless, there little research about vitamin levels regarding COVID-19 date. This study aimed establish relationship between serum 25-hydroxyvitamin (25(OH)D) COVID-19. A comparative case-control was performed population 256 (82 infection 174 control group). Serum 25(OH)D were significantly lower than those without infection. In addition, 89% COVID-19-positive had deficiency, while group percentage 75.30%, finding statistically significant differences (ORa = 2.68; 95% CI 1.19-6.06; p 0.01). Our results find deficiency could relevant for actual clinical practice. Thus, more needed field.

Language: Английский

Citations

44
Sex and Gender Multidimensionality in Epidemiologic Research DOI Creative Commons
Greta R. Bauer

American Journal of Epidemiology, Journal Year: 2022, Volume and Issue: 192(1), P. 122 - 132

Published: Oct. 1, 2022

Along with age and race, sex has historically been a core stratification control variable in epidemiologic research. While recent decades research guidelines institutionalized requirements have incorporated an approach differentiating biological from social gender, neither nor gender is itself unidimensional construct. The conflation of dimensions within between presents validity issue wherein proxy measures are used for interest, often without explicit acknowledgement or evaluation. Here, individual-level outlined as guide epidemiologists, 2 case studies presented. first study demonstrates how unacknowledged use sex/gender sexed dimension interest (uterine status) resulted cancer misestimating risks, racial disparities, trends. second illustrates multidimensional framework may be applied to strengthen on coronavirus disease 2019 incidence, diagnosis, morbidity, mortality. Considerations outlined, including: 1) addressing the match theory, explicitly acknowledging evaluating use; 2) improving measurement across ecological levels; 3) incorporating multidimensionality into objectives; 4) interpreting sex, their effects biopsychosocial.

Language: Английский

Citations

44