Effect of salinity stress on plants and its tolerance strategies: a review

Environmental Science and Pollution Research, Journal Year: 2014, Volume and Issue: 22(6), P. 4056 - 4075

Published: Nov. 15, 2014

Language: Английский

---

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

Cancer Letters, Journal Year: 2013, Volume and Issue: 344(2), P. 174 - 179

Published: Dec. 11, 2013

Language: Английский

---

The Oxytocin Receptor: From Intracellular Signaling to Behavior

Physiological Reviews, Journal Year: 2018, Volume and Issue: 98(3), P. 1805 - 1908

Published: June 14, 2018

The many facets of the oxytocin (OXT) system brain and periphery elicited nearly 25,000 publications since 1930 (see FIGURE 1 , as listed in PubMed), which revealed central roles for OXT its receptor (OXTR) reproduction, social emotional behaviors animal human studies focusing on mental physical health disease. In this review, we discuss mechanisms expression release, binding OXTR periphery, OXTR-coupled signaling cascades, their involvement behavioral outcomes to assemble a comprehensive picture peripheral system. Traditionally known role milk let-down uterine contraction during labor, also has implications physiological, behavioral, aspects such sexual maternal pair bonding, but anxiety, trust, sociability, food intake, or even drug abuse. are, molecular basis, brought about by single receptor. OXTR, 7-transmembrane G protein-coupled capable either Gα i q proteins, activates set MAPK, PKC, PLC, CaMK pathways, converge transcription factors like CREB MEF-2. cellular response includes regulation neurite outgrowth, viability, increased survival. OXTergic projections represent anxiety stress-regulating circuits connecting paraventricular nucleus hypothalamus, amygdala, bed stria terminalis, medial prefrontal cortex. Which OXT-induced patterns finally alter behavior an being is still poorly understood, studying those cascades one initial step toward better understanding background effects.

Language: Английский

---

TNF and MAP kinase signalling pathways

Seminars in Immunology, Journal Year: 2014, Volume and Issue: 26(3), P. 237 - 245

Published: March 20, 2014

Language: Английский

---

Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention

Nutrition Research, Journal Year: 2014, Volume and Issue: 34(11), P. 907 - 929

Published: July 18, 2014

Language: Английский

---

Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems

Chemical Reviews, Journal Year: 2014, Volume and Issue: 114(15), P. 7740 - 7781

Published: June 13, 2014

ADVERTISEMENT RETURN TO ISSUEPREVReviewChemical Basis of Interactions Between Engineered Nanoparticles and Biological SystemsQingxin Mu†, Guibin Jiang§, Lingxin Chen∥, Hongyu Zhou†⊥, Denis Fourches, Alexander Tropsha#, Bing Yan*†View Author Information† School Chemistry Chemical Engineering, Shandong University, Jinan 250100, China§ State Key Laboratory Environmental Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy Beijing, 100085, China∥ Yantai Institute Coastal Zone Research, 264003, China⊥ Department Surgery, Emory University Medicine, Atlanta, Georgia 30322, United States# Molecular Modeling, UNC Eshelman Pharmacy, North Carolina, Chapel Hill, Carolina 27599, States*Phone: +86-531-88380019. Fax: +86-531-88380029. E-mail: [email protected]Cite this: Chem. Rev. 2014, 114, 15, 7740–7781Publication Date (Web):June 13, 2014Publication History Received29 May 2013Published online13 June 2014Published inissue 13 August 2014https://pubs.acs.org/doi/10.1021/cr400295ahttps://doi.org/10.1021/cr400295areview-articleACS PublicationsCopyright © 2014 American SocietyRequest reuse permissionsArticle Views12613Altmetric-Citations466LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated by Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Carbon nanotubes,Genetics,Metal oxide nanoparticles,Molecules,Nanoparticles Get e-Alerts

Language: Английский

---

Mitogen-activated protein kinase cascades in signaling plant growth and development

Trends in Plant Science, Journal Year: 2014, Volume and Issue: 20(1), P. 56 - 64

Published: Oct. 22, 2014

Language: Английский

---

Dual‐specificity MAP kinase phosphatases (MKPs)

FEBS Journal, Journal Year: 2012, Volume and Issue: 280(2), P. 489 - 504

Published: July 20, 2012

Dual‐specificity MAP kinase phosphatases (MKPs) provide a complex negative regulatory network that acts to shape the duration, magnitude and spatiotemporal profile of activities in response both physiological pathological stimuli. Individual MKPs may exhibit either exquisite specificity towards single mitogen‐activated protein (MAPK) isoform or be able regulate multiple MAPK pathways cell tissue. They can act as feedback regulators activity, but also mechanisms crosstalk between distinct signalling other intracellular modules. In this review, we explore current state knowledge with respect regulation MKP expression levels activities, by which individual recognize interact different isoforms their role signalling.

Language: Английский

---

Molecular Biology of Atherosclerosis

Physiological Reviews, Journal Year: 2013, Volume and Issue: 93(3), P. 1317 - 1542

Published: July 1, 2013

At least 468 individual genes have been manipulated by molecular methods to study their effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians many investigators, even in related disciplines, find these pathways entirely foreign. Medical schools generally do not attempt incorporate relevant biology into curriculum. A number key signaling are highly atherogenesis presented provide a context for gene manipulations summarized herein. The include following: insulin receptor (and other tyrosine kinases); Ras MAPK activation; TNF-α family members leading activation NF-κB; reactive oxygen species (ROS) signaling; endothelial adaptations flow including G protein-coupled (GPCR) integrin-related cells modified lipoproteins; purinergic control leukocyte adhesion endothelium, migration, further foam cell formation; macrophage vascular smooth muscle proliferation, efferocytosis, apoptosis. This review is intended primarily as an introduction pathways. They become focus modern atherosclerosis research will undoubtedly rich resource future innovation toward intervention prevention one cause death world.

Language: Английский

---

Diversity and versatility of p38 kinase signalling in health and disease

Nature Reviews Molecular Cell Biology, Journal Year: 2021, Volume and Issue: 22(5), P. 346 - 366

Published: Jan. 27, 2021

Language: Английский

---