Experimental Neurology, Journal Year: 2012, Volume and Issue: 243, P. 4 - 20
Published: July 2, 2012
Language: Английский
Experimental Neurology, Journal Year: 2012, Volume and Issue: 243, P. 4 - 20
Published: July 2, 2012
Language: Английский
Trends in Endocrinology and Metabolism, Journal Year: 2006, Volume and Issue: 17(3), P. 110 - 116
Published: March 7, 2006
Language: Английский
Citations
321Journal of Neuroendocrinology, Journal Year: 2008, Volume and Issue: 20(6), P. 752 - 763
Published: June 1, 2008
The neuroendocrine control of prolactin secretion is unlike that any other pituitary hormone. It predominantly inhibited by the hypothalamus and, in absence a regulatory feedback hormone, it acts directly brain to suppress its own secretion. In addition this short‐loop action brain, has been reported influence wide range functions. There have few attempts rationalise why single hormone might exert such distinct and seemingly unrelated review, we highlight some original studies first characterised unusual features neuroendocrinology, then attempt identify areas new progress and/or controversy. Finally, discuss hypothesis provides unifying explanation for pleiotrophic actions brain.
Language: Английский
Citations
302Journal of Endocrinology, Journal Year: 2015, Volume and Issue: 226(2), P. T101 - T122
Published: June 22, 2015
The hypothalamic control of prolactin secretion is different from other anterior pituitary hormones, in that it predominantly inhibitory, by means dopamine the tuberoinfundibular neurons. In addition, does not have an endocrine target tissue, and therefore lacks classical feedback pathway to regulate its secretion. Instead, regulated short loop feedback, whereby itself acts brain stimulate production thereby inhibit own Finally, despite relatively simple name, has a broad range functions body, addition defining role promoting lactation. As such, hypothalamo-prolactin axis many characteristics are quite distinct hypothalamo-pituitary systems. This review will provide brief overview our current understanding neuroendocrine secretion, particular focusing on plasticity evident this system, which keeps at low levels most time, but enables extended periods hyperprolactinemia when necessary for Key beyond milk be discussed, particularly inducing adaptive responses multiple systems facilitate lactation, consequences if action impaired. A feature pleiotropic activity may lactating state might maladaptive elevated inappropriately. Overall, my goal give flavour both history field neuroendocrinology, identify some exciting new areas research development.
Language: Английский
Citations
301Frontiers in Neuroendocrinology, Journal Year: 2009, Volume and Issue: 30(3), P. 343 - 357
Published: April 9, 2009
Language: Английский
Citations
293Experimental Neurology, Journal Year: 2012, Volume and Issue: 243, P. 4 - 20
Published: July 2, 2012
Language: Английский
Citations
289