Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(11), P. 8990 - 9006
Published: Sept. 15, 2024
Abstract
This
study
evaluates
the
antioxidant
activity
and
total
phenolic,
flavonoid,
flavonol,
tannin
contents
of
extracts
obtained
from
flower
parts
Salvia
sclarea
using
different
extraction
methods,
such
as
maceration
rotavapor
(RE).
The
results
indicate
that
method
yields
with
higher
compared
to
(DPPH
IC
50
:
260.70
±
65.41
mg/mL
vs.
345.48
27.91
mg/mL).
Additionally,
produces
values
in
terms
phenolic
(26.4
7.78
mg
GAE/g
extract),
flavonoid
(10.44
0.21
QE/g
flavonol
(9.20
0.84
(8.36
0.39
whereas
RE
shows
lower
(phenolics:
19.8
3.31
extract,
flavonoids:
10.35
0.35
flavanol's:
5.45
0.01
tannins:
7.72
0.10
extract).
gas
chromatography–mass
spectrometry
(GC–MS)
analysis
identified
various
bioactive
compounds.
Molecular
docking
studies
revealed
Terpinen‐4‐ol
through
exhibits
a
strong
binding
affinity
specific
protein
target,
indicating
potential
biological
activity.
predicted
pharmacokinetic
(ADME
(absorption,
distribution,
metabolism,
excretion))
parameters
for
suggest
favorable
absorption
central
nervous
system
(CNS)
penetration,
while
Squalene
properties.
S.
highlights
significant
provides
insight
into
compounds
methods.
To
further
investigate
interactions
arising
these
differences,
molecular
were
conducted.
Frontiers in Chemistry,
Journal Year:
2024,
Volume and Issue:
12
Published: March 13, 2024
In
recent
years,
there
has
been
a
considerable
rise
in
the
production
of
novel
metabolites
derived
from
fungi
compared
to
ones
originating
bacteria.
These
organic
substances
are
utilized
various
sectors
such
as
farming,
healthcare,
and
pharmaceutical.
Since
all
dividing
living
cells
contain
primary
metabolites,
secondary
synthesized
by
utilizing
intermediate
compounds
or
by-products
generated
metabolic
pathways.
Secondary
not
critical
for
growth
development
an
organism;
however,
they
exhibit
variety
distinct
biological
characteristics.
White-rot
only
microorganisms
able
decompose
wood
components.
Hence,
play
important
role
both
carbon
nitrogen
cycles
decomposing
non-living
substrates.
They
ubiquitous
nature,
particularly
hardwood
(e.g.,
birch
aspen)
forests.
fungi,
besides
ligninolytic
enzymes,
produce
different
bioactive
during
their
metabolism
including
some
with
antimicrobial
anticancer
properties.
Such
properties
could
be
potential
interest
pharmaceutical
industries.
Considering
importance
untapped
biologically
active
white-rot
present
paper
reviews
produced
interesting
bioactivities.
ECS Journal of Solid State Science and Technology,
Journal Year:
2024,
Volume and Issue:
13(8), P. 087003 - 087003
Published: July 22, 2024
This
research
explores
the
eco-friendly
creation
of
functional,
biocompatible
nanomaterials
through
green
chemistry,
utilizing
natural
extracts
over
chemicals
to
produce
metal
and
oxide
nanoparticles.
The
study
focuses
on
iron
nanoparticles
synthesized
with
Volvariella
volvacea
(GIONP)
evaluates
their
physical,
chemical,
biological
traits,
including
anticancer
capabilities,
against
traditionally
made
IONPs
(CIONP).
GIONPs,
confirmed
by
UV-visible
spectroscopy
dynamic
light
scattering,
showed
enhanced
stability
consistent
size
distribution.
They
also
demonstrated
smaller
sizes
via
-Field
Emission
scanning
electron
microscopy
analysis,
X-ray
diffraction
Fourier
transform
infrared
studies
verified
crystalline
structure
organic
functional
groups.
Notably,
GIONPs
exhibited
strong
antioxidant
properties,
low
toxicity
blood
cells,
promising
for
intravenous
use,
greater
antimicrobial
antibiofilm
activities
various
bacterial
strains
than
CIONPs.
revealed
that
both
CIONPs
exhibit
a
similar
degree
towards
MDA-MB
231
cancer
cells.
internalization
within
these
cells
was
Prussian
blue
assay
further
supported
concentration-dependent
increase
in
intracellular
levels
post-treatment.
These
findings
underscore
successful
formulation
are
not
only
but
capped
bioactive
compounds,
highlighting
applications
field
biomedicine.
International Journal of Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
2023, P. 1 - 20
Published: Sept. 22, 2023
Secondary
metabolites
are
hidden
gems
in
mushrooms.
Understanding
these
secondary
metabolites'
biological
and
pharmacological
effects
can
be
aided
by
identifying
them.
The
purpose
of
this
work
was
to
profile
the
mycochemical
components
extracts
Auricularia
auricula
judae,
Microporus
xanthopus,
Termitomyces
umkowaani,
Trametes
elegans,
versicolor
comprehend
their
capabilities.
Mushroom
samples
were
collected
from
Kenya's
Arabuko-Sokoke
Kakamega
National
Reserved
Forests
identified
using
morphological
molecular
techniques.
Chloroform,
70%
ethanol,
hot
water
solvents
used
extract
components.
Gas
chromatography
mass
spectrometry
(GC-MS)
analyze
chloroform,
all
species
examined.
A
total
51
compounds
isolated
classified
as
carboxylic
acids,
esters,
phenols,
fatty
alcohol,
epoxides,
aldehydes,
isoprenoid
lipids,
steroids.
Tetracosamethyl-cyclododecasiloxane
(18.90%),
oleic
acid
(72.90%),
phenol,
2,
6-bis
(1,
1-dimethylethyl)-4-methyl-,
methylcarbamate
(26.56%)
found
high
concentrations
A.
auricular
M.
T.
versicolor,
respectively.
Fatty
acids
make
up
majority
elegans
chloroform
umkowaani
ethanol
extract,
Particularly,
play
crucial
roles
anti-inflammatory,
hypocholesterolemic,
anticancer,
antibiofilm
formation
activities.
These
bioactive
elements
indicate
that
five
wild
mushrooms
may
reliable
sources
for
therapeutic
development.
Therefore,
additional
research
is
required
usefulness
chemicals
many
functional
areas
improve
present
understanding
macrofungi.
International Journal of Life Sciences,
Journal Year:
2025,
Volume and Issue:
9(1), P. 1 - 15
Published: April 15, 2025
Considering
the
current
situation,
relatively
little
research
has
been
conducted
on
wild
mushrooms
to
date.
Many
species
of
are
found
in
nature.
Discovering
new
these
hidden
mushrooms,
properly
identifying
them,
exploring
compounds
and
writing
literature
would
be
novel
future.
In
this
way,
properties
diversity
can
further
explored.
Wild
a
valuable
source
pharmacologically
active
substances,
nutraceuticals,
cosmeceuticals,
which
could
exploited
for
diverse
medical
applications
future,
particularly
those
requiring
accurate
pharmacogenetic
fingerprints.
The
purpose
present
review
study
is
compile
information
discovered
by
our
scientists
researchers
from
different
places
discuss
their
medicinal
nutraceutical
properties.
So
data
guidance
obtained
future
work.
Journal of Food Biochemistry,
Journal Year:
2023,
Volume and Issue:
2023, P. 1 - 26
Published: Dec. 12, 2023
Mushrooms
have
long
been
revered
not
only
as
a
staple
food
source
but
also
for
their
potential
medicinal
properties.
Their
role
natural
repository
of
bioactive
compounds
positions
them
uniquely
in
the
pharmaceutical
domain,
with
particular
relevance
to
cosmeceuticals
and
nutricosmetics.
The
global
ethnobotanical
ethnopharmacological
chronicles
highlight
traditional
application
mushrooms
against
many
diseases,
even
finding
way
into
cosmetic
formulations.
This
review
aims
consolidate
existing
knowledge
regarding
efficaciousness
mushroom-derived
bioactives
realm
skin
disorders
diseases.
In
addition,
it
sheds
light
on
instances
where
certain
mushroom
species
implicated
causing
dermatological
reactions,
underscoring
dual
nature
these
fungal
entities.
A
comprehensive
assessment
was
undertaken
involving
databases
relevant
scientific
literature
identify
used
traditionally
treating
conditions.
contemporary
research
elucidating
biological
activities
mushrooms,
specifically
antioxidant,
anti-inflammatory,
antimicrobial,
wound-healing
capabilities,
scrutinized.
Special
attention
accorded
contact
dermatitis
induced
by
notably
shiitake
fungus.
Preliminary
findings
reinforce
therapeutic
managing
ailments,
attributed
primarily
antimicrobial
Conversely,
some
species,
prominently
shiitake,
emerged
potent
triggers.
undeniably
harbor
an
array
that
can
be
instrumental
various
conditions,
thereby
applications.
However,
understanding
nature,
acting
both
remedy
trigger
is
essential
judicious
care.
Further
mandated
unravel
pharmacological
spectrum
treasures.
Journal of Asian Natural Products Research,
Journal Year:
2024,
Volume and Issue:
26(12), P. 1551 - 1556
Published: June 28, 2024
The
undescribed
phosphatidylcholine
(1),
along
with
twelve
known
compounds,
was
isolated
from
the
cultures
of
white
rot
fungus
Microporus
xanthropus
PP17-20.
In
this
work
cultivated
in
Yeast-Malt
extract
medium
to
explore
active
compound
production.
chemical
structures
were
elucidated
on
basis
spectroscopic
and
HRESIMS
data.
Several
compounds
evaluated
for
anti-proliferative
activity
against
A549
MCF-7
cancer
cell
lines.
