Mechanisms of heart valve development and disease DOI Open Access
Anna O’Donnell, Katherine E. Yutzey

Development, Journal Year: 2020, Volume and Issue: 147(13)

Published: July 1, 2020

The valves of the heart are crucial for ensuring that blood flows in one direction from heart, through lungs and back to rest body. Heart valve development is regulated by complex interactions between different cardiac cell types subject flow-driven forces. Recent work has begun elucidate important roles developmental pathways, heterogeneity hemodynamics determining structure function developing valves. Furthermore, this revealed many key genetic pathways involved also implicated diseased Here, we review recent discoveries have furthered our understanding molecular, cellular mechanosensitive mechanisms development, highlight new insights into congenital acquired disease.

Language: Английский

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association DOI Creative Commons
Emelia J. Benjamin, Paul Muntner, Álvaro Alonso

et al.

Circulation, Journal Year: 2019, Volume and Issue: 139(10)

Published: Jan. 31, 2019

Language: Английский

Citations

8010
Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association DOI Creative Commons
Salim S. Virani, Álvaro Alonso, Emelia J. Benjamin

et al.

Circulation, Journal Year: 2020, Volume and Issue: 141(9)

Published: Jan. 29, 2020

The American Heart Association, in conjunction with the National Institutes of Health, annually reports on most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).The through its Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual Update. 2020 is product full year's worth effort by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. This edition includes monitoring benefits population, metrics assess monitor healthy diets, an enhanced focus social determinants health, global burden further evidence-based approaches changing behaviors, implementation strategies, implications Association's Impact Goals.Each 26 chapters focuses different topic statistics.The represents critical resource for lay public, policy makers, media clinicians, healthcare administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

Citations

7738
Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association DOI Creative Commons
Emelia J. Benjamin, Salim S. Virani, Clifton W. Callaway

et al.

Circulation, Journal Year: 2018, Volume and Issue: 137(12)

Published: Jan. 31, 2018

Each chapter listed in the Table of Contents (see next page) is a hyperlink to that chapter. The reader clicks name access chapter. Each here hyperlink. Click on be taken Each year, American Heart Association (AHA), conjunction with Centers for Disease Control and Prevention, National Institutes Health, other government agencies, brings together single document most up-to-date statistics related heart disease, stroke, cardiovascular risk factors AHA’s My Life Check - Life’s Simple 7 (Figure1), which include core health behaviors (smoking, physical activity, diet, weight) (cholesterol, blood pressure [BP], glucose control) contribute health. Statistical Update represents …

Language: Английский

Citations

6728
Heart Disease and Stroke Statistics—2021 Update DOI Creative Commons
Salim S. Virani, Álvaro Alonso, Hugo J. Aparicio

et al.

Circulation, Journal Year: 2021, Volume and Issue: 143(8)

Published: Jan. 27, 2021

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).The through its Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual Update. 2021 is product full year's worth effort by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. This edition includes monitoring benefits population, an enhanced focus social determinants health, adverse pregnancy outcomes, vascular contributions brain global burden further evidence-based approaches changing disease.Each 27 chapters focuses different topic statistics.The represents critical resource for lay public, policy makers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

Citations

4712
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association DOI Creative Commons

Connie W. Tsao,

Aaron W. Aday, Zaid Almarzooq

et al.

Circulation, Journal Year: 2022, Volume and Issue: 145(8)

Published: Jan. 26, 2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).

Language: Английский

Citations

4265
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association DOI Creative Commons

Connie W. Tsao,

Aaron W. Aday, Zaid Almarzooq

et al.

Circulation, Journal Year: 2023, Volume and Issue: 147(8)

Published: Jan. 25, 2023

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs). Methods: through its Epidemiology Prevention Statistics Committee, continuously monitors evaluates sources stroke United States provide current information available annual review published literature year before writing. 2023 is product full year’s worth effort 2022 by dedicated volunteer clinicians scientists, committed government professionals, Association staff members. strives further understand help heal problems inflicted structural racism, public crisis can significantly damage mental perpetuate disparities access education, income, housing, several other vital healthy lives. This edition includes additional COVID-19 (coronavirus 2019) publications, as well monitoring benefits population, an enhanced focus equity across key domains. Results: Each chapters focuses different topic statistics. Conclusions: represents critical resource for lay public, policymakers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

Citations

4232
Handbook of Religion and Health DOI
Harold G. Koenig, Tyler J. VanderWeele, John R. Peteet

et al.

Oxford University Press eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 23, 2023

Abstract The 2001 (first) edition of this Handbook was a comprehensive review history, research, and discussions on religion health through the year 2000. Appendix listed 1,200 separate quantitative studies each rated in quality 0–10 scale, followed by about 2,000 references an extensive index for rapid topic identification. 2012 (second) systematically updated research from 2000 to 2010, with number then reaching thousands. This 2023 (third) is most scientifically rigorous date, covering best published 2021 emphasis prospective randomized controlled trials. Beginning Foreword Dr. Howard K. Koh, former US Assistant Secretary Health Department Human Services, nearly 600,000-word volume examines almost every aspect health, reviewing past more recent relationship between outcomes. Furthermore, all its 34 chapters conclude clinical community applications, making text relevant both healthcare professionals (physicians, nurses, social workers, rehabilitation therapists, counselors, psychologists, sociologists, etc.) clergy (community clergy, chaplains, pastoral etc.). book’s focuses studies, describing study single line, allowing researchers quickly locate existing research. It should not be surprising that two decades has been cited health.

Language: Английский

Citations

1065
Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies DOI Creative Commons
Yingjuan Liu,

Sen Chen,

Liesl Zühlke

et al.

International Journal of Epidemiology, Journal Year: 2019, Volume and Issue: 48(2), P. 455 - 463

Published: Jan. 29, 2019

Globally, access to healthcare and diagnostic technologies are known substantially impact the reported birth prevalence of congenital heart disease (CHD). Previous studies have shown marked heterogeneity between different regions, with a suggestion that CHD is rising globally, but degree which this reflects differences due environmental or genetic risk factors, as opposed improved detection, uncertain. We performed an updated systematic review address these issues.Studies reporting years 1970-2017 were identified from searches PubMed, EMBASE, Web Science Google Scholar. Data on total 27 anatomical subtypes collected. combined using random-effect models. Subgroup meta-regression analyses conducted, focused geographical regions levels national income.Two hundred sixty met inclusion criteria, encompassing 130 758 851 live births. The progressively increased maximum in period 2010-17 9.410/1000 [95% CI (confidence interval) 8.602-10.253]. This represented significant increase over fifteen prior (P = 0.031). change mild lesions (ventricular septal defect, atrial defect patent ductus arteriosus) together explained 93.4% overall prevalence, consistent major role postnatal detection less severe lesions. In contrast grouped left ventricular outflow tract obstruction (which includes hypoplastic syndrome) decreased 0.689/1000 (95% 0.607-0.776) 1995-99, 0.475/1000 0.392-0.565; P 0.004) 2010-17, would be prenatal consequent termination pregnancy when very discovered. There was among Africa lowest [2.315/1000 0.429-5.696)] Asia highest [9.342/1000 8.072-10.704)].The globally continues increase, evidence unmet need Africa. recent for first time appears higher than Europe America, where ascertainment likely near-complete, suggesting susceptibility Asian people.

Language: Английский

Citations

999
2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association DOI Creative Commons
Seth S. Martin, Aaron W. Aday, Zaid Almarzooq

et al.

Circulation, Journal Year: 2024, Volume and Issue: 149(8)

Published: Jan. 24, 2024

BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, obesity) factors (cholesterol, blood pressure, glucose control, metabolic syndrome) that contribute health. AHA Disease Stroke Statistical Update presents latest data on a range major clinical circulatory disease conditions (including brain health, complications pregnancy, kidney congenital rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary cardiomyopathy, failure, valvular venous thromboembolism, peripheral artery disease) associated outcomes quality care, procedures, economic costs). METHODS: AHA, through its Epidemiology Prevention Statistics Committee, continuously monitors evaluates sources stroke United States globally provide current information available annual review published literature year before writing. 2024 is product full year’s worth effort 2023 by dedicated volunteer clinicians scientists, committed government professionals, staff members. strives further understand help heal problems inflicted structural racism, public crisis can significantly damage mental perpetuate disparities access education, income, housing, several other vital healthy lives. This edition includes additional global data, as well monitoring benefits population, an enhanced focus equity across key domains. RESULTS: Each chapters focuses different topic statistics. CONCLUSIONS: represents critical resource for lay public, policymakers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

Citations

914
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands DOI
Sheng Chih Jin,

Jason Homsy,

Samir Zaidi

et al.

Nature Genetics, Journal Year: 2017, Volume and Issue: 49(11), P. 1593 - 1601

Published: Oct. 9, 2017

Language: Английский

Citations

763