BMC Biology,
Journal Year:
2022,
Volume and Issue:
20(1)
Published: June 15, 2022
Abstract
Background
Circadian
rhythms
are
important
for
all
aspects
of
biology;
virtually
every
aspect
biological
function
varies
according
to
time
day.
Although
this
is
well
known,
variation
across
the
day
also
often
ignored
in
design
and
reporting
research.
For
review,
we
analyzed
top
50
cited
papers
10
major
domains
sciences
calendar
year
2015.
We
repeated
analysis
2019,
hypothesizing
that
awarding
a
Nobel
Prize
2017
achievements
field
circadian
biology
would
highlight
importance
scientists
many
disciplines,
improve
time-of-day
reporting.
Results
Our
analyses
these
1000
empirical
papers,
however,
revealed
most
failed
include
sufficient
temporal
details
when
describing
experimental
methods
few
systematic
differences
existed
between
2015
2019.
Overall,
only
6.1%
reports
included
information
about
measures
manipulations
permit
replication.
Conclusions
defining
feature
systems,
knowing
systems
evaluated
fundamentally
information.
Failing
account
hampers
reproducibility
laboratories,
complicates
interpretation
results,
reduces
value
data
based
predominantly
on
nocturnal
animals
extrapolating
diurnal
humans.
Journal of science and medicine in sport,
Journal Year:
2020,
Volume and Issue:
23(7), P. 670 - 679
Published: May 19, 2020
To
describe
the
perceptions
of
South
African
elite
and
semi-elite
athletes
on
return
to
sport
(RTS);
maintenance
physical
conditioning
other
activities;
sleep;
nutrition;
mental
health;
healthcare
access;
knowledge
coronavirus
disease
2019
(COVID-19).
Journal of Neuroscience,
Journal Year:
2021,
Volume and Issue:
41(37), P. 7698 - 7711
Published: Sept. 15, 2021
Throughout
the
body,
lymphatic
fluid
movement
supports
critical
functions
including
clearance
of
excess
and
metabolic
waste.
The
glymphatic
system
is
analog
in
CNS.
As
such,
plays
a
key
role
regulating
directional
interstitial
movement,
waste
clearance,
and,
potentially,
brain
immunity.
enables
bulk
CSF
from
subarachnoid
space
along
periarterial
spaces,
where
it
mixes
with
within
parenchyma
before
ultimately
exiting
via
perivenous
spaces.
This
review
focuses
on
important
questions
about
structure
this
system,
why
needs
transport
unexplored
aspects
transport.
We
provide
evidence
that
astrocytes
blood
vessels
determine
shape
perivascular
space,
controlling
fluid.
Glymphatic
has
potential
to
alter
local
as
well
global
signaling
molecules
metabolites.
also
highlight
for
cross
talk
among
cardiovascular
gastrointestinal
tract,
system.
Much
remains
be
studied,
but
we
propose
glymphatic/lymphatic
acts
cornerstone
between
body.
The Lancet Public Health,
Journal Year:
2023,
Volume and Issue:
8(10), P. e820 - e826
Published: Sept. 28, 2023
Healthy
sleep
is
essential
for
physical
and
mental
health,
social
wellbeing;
however,
across
the
globe,
particularly
in
developing
countries,
national
public
health
agendas
rarely
consider
health.
Sleep
should
be
promoted
as
an
pillar
of
equivalent
to
nutrition
activity.
To
improve
a
focus
on
education
awareness,
research,
targeted
policies
are
needed.
We
recommend
educational
programmes
awareness
campaigns;
increasing,
standardising,
centralising
data
quantity
quality
every
country
globe;
implementing
sectors
society.
Efforts
needed
ensure
equity
inclusivity
all
people,
those
who
most
socially
economically
vulnerable,
historically
excluded.
Chronobiology International,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 14
Published: Jan. 6, 2025
Seven-day
actigraphy
was
performed
within
1
month
in
122
community-dwelling
adults
(mean
age
24.40
y,
31
(25.4%)
men)
the
same
city
of
Tyumen,
Russia.
Groups
with
different
COVID-19
status
(present,
COVID-19(+),
Naunyn-Schmiedeberg s Archives of Pharmacology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 10, 2025
Abstract
One
of
the
goals
clinical
pharmacology
is
to
optimize
patient
treatment
by
adopting
new
strategies
which
will
increase
efficacy
and
decrease
adverse
effects
drugs.
In
literature,
it
has
shown
that
effectiveness
toxicity
medications
can
vary
significantly
based
on
when
they
are
administered,
making
timing
a
crucial
factor
in
plans.
Chronopharmacology
relatively
branch
focuses
adjusting
drug
administration
times
enhance
outcomes.
largely
influenced
an
individual’s
circadian
rhythm
refers
periodic
changes
biological
processes
depending
time
day.
The
chronopharmacology
influences
practice,
accumulating
knowledge
this
field
likely
lead
healthcare
providers
adopt
for
regimens.
This
review
aims
summarize
impact
particularly
current
practices
highlight
latest
findings
related
chronophysiological
mechanisms.
British Journal Of Nutrition,
Journal Year:
2020,
Volume and Issue:
125(8), P. 851 - 862
Published: Aug. 26, 2020
Abstract
COVID-19,
caused
by
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2),
was
recognised
the
WHO
as
a
pandemic
in
2020.
Host
preparation
to
combat
virus
is
an
important
strategy
avoid
COVID-19
severity.
Thus,
relationship
between
eating
habits,
nutritional
status
and
their
effects
on
immune
response
further
implications
viral
infections
topic
discussed
this
review.
Malnutrition
causes
most
diverse
alterations
system,
suppressing
of
increasing
susceptibility
such
SARS-CoV-2.
On
other
hand,
obesity
induces
low-grade
chronic
inflammation
excess
adiposity,
which
increases
angiotensin-converting
enzyme
2.
It
decreases
favouring
SARS-CoV-2
virulence
promoting
distress
syndrome.
The
present
review
highlights
importance
food
choices
considering
inflammatory
effects,
consequently
observed
malnutrition
obesity.
Healthy
micronutrients,
bioactive
compounds
probiotics
are
strategies
for
prevention.
Therefore,
diversified
balanced
diet
can
contribute
improvement
COVID-19.
Journal of Translational Medicine,
Journal Year:
2020,
Volume and Issue:
18(1)
Published: Aug. 18, 2020
Abstract
Background
COVID
19
-
related
quarantine
led
to
a
sudden
and
radical
lifestyle
changes,
in
particular
eating
habits.
Objectives
of
the
study
were
investigate
effect
on
sleep
quality
(SQ)
body
mass
index
(BMI),
if
change
SQ
was
working
modalities.
Materials
We
enrolled
121
adults
(age
44.9
±
13.3
years
35.5%
males).
Anthropometric
parameters,
modalities
physical
activity
studied.
Sleep
evaluated
by
Pittsburgh
Quality
Index
(PSQI)
questionnaire.
At
baseline,
subjects
assessed
outpatient
clinic
after
40
days
quarantine/lockdown
phone
interview.
Results
Overall,
49.6%
good
sleepers
(PSQI
<
5)
at
baseline
significantly
decreased
(
p
0.001).
In
detail,
onset
latency
0.001),
efficiency
=
0.03),
disturbances
daytime
dysfunction
0.001)
worsened.
There
also
significant
increase
BMI
values
normal
weight
0.023),
grade
I
0.027)
II
obesity
0.020).
all
cohort,
0.004).
However,
analyzing
data
according
gender
difference,
males
as
well
females
which
there
only
trend
without
reaching
statistical
significance
(53.5%
vs
25.6%;
0.015
50.0%
35.9%,
0.106;
females,
respectively).
addition,
smart
resulted
worsening
SQ,
particularly
Conclusions
Quarantine
associated
doing
working,
an
values.
Frontiers in Nutrition,
Journal Year:
2020,
Volume and Issue:
7
Published: Nov. 19, 2020
Background:
COVID-19
is
a
global
challenge
to
healthcare.
Obesity
common
in
patients
with
and
seems
aggravate
disease
prognosis.
In
this
review
we
explore
the
link
between
obesity,
chronic
disease,
lifestyle
factors
immune
system,
propose
societal
interventions
enhance
immunity.
Search
Strategy
Selection
Criteria:
We
performed
three
literature
searches
using
keywords
(1)
coronavirus
AND
comorbidities,
(2)
comorbidities
(3)
system.
Results
were
screened
for
relevance
by
main
author
total
of
215
articles
thoroughly
analyzed.
Results:
The
relationship
obesity
unfavorable
prognosis
discussed
light
impact
on
Several
modifiable
render
us
susceptible
viral
infections.
context,
make
case
fostering
healthy
scale.
Conclusions:
Obesity,
additional
an
unhealthy
interactively
impair
function
increase
risk
severe
infectious
disease.
adverse
metabolic
endocrine
conditions,
system
geared
toward
inflammation.
Collective
effort
needed
ameliorate
scale
resistance
viruses
like
SARS-CoV-2.
