Gut microbiota: a new avenue to reveal pathological mechanisms of constipation DOI
Lei Yang, Yu Wang, Yun Zhang

et al.

Applied Microbiology and Biotechnology, Journal Year: 2022, Volume and Issue: 106(21), P. 6899 - 6913

Published: Oct. 3, 2022

Language: Английский

A Randomized Clinical Trial to Evaluate the Efficacy of an Oral Probiotic in Acne Vulgaris DOI Creative Commons

C. Eguren,

Ariadna Navarro-Blasco,

Marina Corral‐Forteza

et al.

Acta Dermato Venereologica, Journal Year: 2024, Volume and Issue: 104, P. adv33206 - adv33206

Published: May 15, 2024

The relevance of the gut microbiota in some skin inflammatory diseases, including acne vulgaris, has been emphasized. Probiotics could play a role modulation microbiota, improving clinical course this disease. A 12-week randomized, double-blind, placebo-controlled, trial with patients aged 12 to 30 years vulgaris was conducted. study product capsule composed probiotic Lacticaseibacillus rhamnosus (CECT 30031) and cyanobacterium Arthrospira platensis (BEA_IDA_0074B). Patients improvement Acne Global Severity Scale were 10/34 (29.41%) placebo group compared 20/40 (50%) (p = 0.03). significant reduction 0.03) number non-inflammatory lesions observed (–18.60 [–24.38 –12.82]) vs (–10.54 [–17.43 –3.66]). Regarding total lesions, almost reaching statistical significance 0.06) (–27.94 [–36.35 –19.53]) (–18.31 [–28.21 –8.41]). In addition, attending Grading System 7/34 (20.58%) 17/40 (42.50%) 0.02). adverse events similar both groups. used effective well tolerated, it should be considered for patients.

Language: Английский

Citations

8
State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus DOI Creative Commons
Julie Rodriguez,

Zahra Hassani,

Carolina Alves Costa Silva

et al.

The Lancet Microbe, Journal Year: 2024, Volume and Issue: unknown, P. 100948 - 100948

Published: Sept. 1, 2024

Language: Английский

Citations

8
Influence of selected dosages of plastic microparticles on the porcine fecal microbiome DOI Creative Commons
Ismena Gałęcka, Andrzej Rychlik, Jarosław Całka

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 8, 2025

Abstract Studies conducted so far have shown that nano- and microplastic may disturb the intestinal microenvironment by interacting with epithelium gut microbiota. Depending on research model used, effect microbiome is different—an increase or decrease in selected taxa resulting development of dysbiosis. Dysbiosis be associated inflammation, mental disorders diabetes. The aim study was to analyze 15 gilts divided into 3 groups (n = 5; control group, receiving micropartices at a dose 0.1 g/day (LD) 1 (HD)). Feaces were collected before after 28 days exposure PET microplastics. analysis performed using next-generation sequencing. Alpha beta diversity indices compared, showing, repetition affected only abundance LD groups, but not HD group. relationships between number reads phylum, genus species level calculated statistical methods ( r -Pearson correlation, generalized regression model, variance). revealed, populations Family XIII AD3011 group , Coprococcus V9D2013 UCG-010 Sphaerochaeta increased increasing MP-PET dose. above-mentioned are mainly responsible for production short-chain fatty acids (SCFA). It assumed, SCFA one mechanisms involved response oral MP-PET.

Language: Английский

Citations

1
A Consensus Statement on establishing causality, therapeutic applications and the use of preclinical models in microbiome research DOI
Amira Metwaly, Aïcha Kriaa,

Zahra Hassani

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Language: Английский

Citations

1
Gut microbiota: a new avenue to reveal pathological mechanisms of constipation DOI
Lei Yang, Yu Wang, Yun Zhang

et al.

Applied Microbiology and Biotechnology, Journal Year: 2022, Volume and Issue: 106(21), P. 6899 - 6913

Published: Oct. 3, 2022

Language: Английский

Citations

34