Childhood Maltreatment and Depression: The Role of Emotion Regulation and Irrational Beliefs DOI Open Access
Aslı Burçak TAŞÖREN

OPUS Toplum Araştırmaları Dergisi, Journal Year: 2025, Volume and Issue: 22(1), P. 46 - 63

Published: Feb. 16, 2025

Numerous factors contribute to the relationship between childhood maltreatment and depressive symptoms in later life, with emotion dysregulation being a key component. This study explored mediating role of difficulties regulation irrational beliefs symptoms. The Childhood Trauma Questionnaire (CTQ), Beck Depression Inventory (BDI), Difficulties Emotion Regulation Scale (DERS-16), Shortened General Attitude Belief (SGABS) were administered total 354 participants aged 18-61. Structural equation modeling (SEM) was employed test several models. initial model proposed that link depression would be mediated by beliefs. results indicated did not fit data showed no significant depression, leading its removal from model. In subsequent models, subscales CTQ examined. found fully mediate emotional abuse, sexual physical while partially neglect subscales. Results highlight importance understanding multiple mechanisms involved adult symptomatology.

Language: Английский

Adverse Childhood Experiences and Adult Mental Health Outcomes DOI Creative Commons
Hilda Björk Daníelsdóttir, Thor Aspelund, Qing Shen

et al.

JAMA Psychiatry, Journal Year: 2024, Volume and Issue: 81(6), P. 586 - 586

Published: March 6, 2024

Exposure to adverse childhood experiences (ACEs) has consistently been associated with multiple negative mental health outcomes extending into adulthood. However, given that ACEs and psychiatric disorders cluster within families, it remains be comprehensively assessed what extent familial confounding contributes associations between clinically confirmed adult disorders.

Language: Английский

Citations

73
Prospective and Retrospective Measures of Child Maltreatment and Their Association With Psychopathology DOI
Jessie R. Baldwin, Oonagh Coleman, Emma Francis

et al.

JAMA Psychiatry, Journal Year: 2024, Volume and Issue: 81(8), P. 769 - 769

Published: May 1, 2024

Importance Prospective and retrospective measures of childhood maltreatment identify largely different groups individuals. However, it is unclear if these are differentially associated with psychopathology. Objective To analyze the associations prospective Data Sources Based on a preregistered protocol, Embase, PsycInfo, MEDLINE were searched for peer-reviewed studies published by January 1, 2023, that measured child Study Selection Titles abstracts all articles captured search full texts potentially eligible independently screened 2 authors. Observational association psychopathology included. Extraction Synthesis Multiple investigators extracted data. Multilevel random-effects meta-analyses used to pool results test predictors heterogeneity. Main Outcome Measures Associations between or psychopathology, both unadjusted adjusted (ie, measures, vice versa), moderation preselected variables. Results The based 24 including 15 485 individuals (51.0% female; mean age, 21.3 years at report). Retrospective showed stronger relative in analyses (retrospective measures: odds ratio [OR], 2.21; 95%, 1.94-2.42 vs OR, 1.56; 95% CI, 1.39-1.76) 2.14; 1.90-2.42 1.27; 1.13-1.41). There was no statistically significant when assessment self-reports focused internalizing emotional disorders. Conclusions Relevance Psychopathology more strongly measures—which capture first-person, subjective appraisal events reflected memory recall—compared essentially third-person accounts such events. Maltreatment-related may be driven interpretations experiences, distressing memories, schemas, which could targeted cognitive interventions.

Language: Английский

Citations

36
Burden of Mental Disorders and Suicide Attributable to Childhood Maltreatment DOI
Lucinda Grummitt, Jessie R. Baldwin,

Johanna Lafoa’i

et al.

JAMA Psychiatry, Journal Year: 2024, Volume and Issue: 81(8), P. 782 - 782

Published: May 8, 2024

The proportion of mental disorders and burden causally attributable to childhood maltreatment is unknown.

Language: Английский

Citations

25
Tools for assessing quality and risk of bias in Mendelian randomization studies: a systematic review DOI Creative Commons
Francesca Spiga, Mark Gibson, Sarah Dawson

et al.

International Journal of Epidemiology, Journal Year: 2022, Volume and Issue: 52(1), P. 227 - 249

Published: July 28, 2022

Abstract Background The use of Mendelian randomization (MR) in epidemiology has increased considerably recent years, with a subsequent increase systematic reviews MR studies. We conducted review tools designed for assessing risk bias and/or quality evidence studies and Methods systematically searched MEDLINE, Embase, the Web Science, preprints servers Google Scholar articles containing assessing, conducting reporting also protocols From eligible we collected data on tool characteristics content, as well details narrative description assessment. Results Our searches retrieved 2464 records to screen, from which 14 tools, 35 38 were included our review. Seven bias/quality evaluation their content revealed that all seven addressed three core assumptions instrumental variable analysis, violation can potentially introduce analysis estimates. Conclusion present an overview methods assess analysis. Issues commonly relate standard variables analyses, choice genetic instrument(s) features population(s) are (particularly two-sample MR), addition more traditional non-MR-specific epidemiological biases. identified should be tested validated general before recommendations made widespread use. findings raise awareness about importance related provide information is useful assessment context reviews.

Language: Английский

Citations

53
A genetically informed Registered Report on adverse childhood experiences and mental health DOI
Jessie R. Baldwin, Hannah Sallis, Tabea Schoeler

et al.

Nature Human Behaviour, Journal Year: 2022, Volume and Issue: 7(2), P. 269 - 290

Published: Dec. 8, 2022

Language: Английский

Citations

46
Adverse Life Experiences and Brain Function DOI Creative Commons
Niki Hosseini-Kamkar,

Mahdieh Varvani Farahani,

Maja Nikolic

et al.

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(11), P. e2340018 - e2340018

Published: Nov. 1, 2023

Importance Adverse life experiences have been proposed to contribute diverse mental health problems through an association with corticolimbic functioning. Despite compelling evidence from animal models, findings studies in humans mixed; activation likelihood estimation (ALE) meta-analyses failed identify a consistent of adverse events brain function. Objective To investigate the adversity exposure altered reactivity using multilevel kernel density analyses (MKDA), meta-analytic approach considered more robust than ALE small sample sizes and methodological differences between studies. Data Sources Searches were conducted PsycInfo, Medline, EMBASE, Web Science inception May 4, 2022. The following search term combinations used for each database: trauma , posttraumatic stress disorder ( PTSD ), abuse maltreatment poverty or ; functional magnetic resonance imaging fMRI ) neuroimaging; emotion regulation memory processing inhibitory control executive functioning reward . Study Selection Task-based within 4 domains (emotion processing, control, processing) that included measure whole-brain coordinate results reported Talairach Montreal Neurological Institute space included. Conference abstracts, books, reviews, meta-analyses, opinions, studies, articles not English, fewer 5 participants excluded. Extraction Synthesis Using Preferred Reporting Items Systematic Reviews Meta-Analyses reporting guideline, 2 independent reviewers assessed abstracts full-text entry criteria. A third reviewer resolved conflicts errors data extraction. pooled random-effects model analysis occurred August November Main Outcomes Measures Peak x-axis (left-right), y-axis (posterior-anterior), z-axis (inferior-superior) coordinates extracted all submitted MKDA meta-analyses. Results total 83 meta-analysis, yielding combined 5242 801 coordinates. Adversity was associated higher amygdala (familywise error rate corrected at P < .001; = 22; −4; −17) lower prefrontal cortical 10; 60; 10) across range task domains. These responses only observed adult clearest among those who had exposed severe threat trauma. Conclusions Relevance In this meta-analysis function, prior challenges. might better how diminishes ability cope later stressors produces enduring susceptibility problems.

Language: Английский

Citations

31
The future of neuroscience in developmental psychopathology DOI Creative Commons
Luke W. Hyde, Jessica L. Bezek, Cleanthis Michael

et al.

Development and Psychopathology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: March 6, 2024

Abstract Developmental psychopathology started as an intersection of fields and is now a field itself. As we contemplate the future this field, consider ways in which newer, interdisciplinary – human developmental neuroscience can inform, be informed by, psychopathology. To do so, outline principles how they are and/or implemented neuroscience. In turn, highlight collaboration between these lead to richer models more impactful translation. doing describe from enrich directions for

Language: Английский

Citations

10
Psychiatric and neurological morbidity predicts sexual offending: A nationwide, population-based, case-control study DOI
Kelly M. Babchishin, Michael C. Seto, Niklas Långström

et al.

Journal of Criminal Justice, Journal Year: 2025, Volume and Issue: 96, P. 102355 - 102355

Published: Jan. 1, 2025

Language: Английский

Citations

1
A Systematic Review and Meta‐Analysis of the Association Between Childhood Maltreatment and Adult Depression DOI Creative Commons
Charles G. Watson, Christopher F. Sharpley, Vicki Bitsika

et al.

Acta Psychiatrica Scandinavica, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

ABSTRACT Introduction Childhood maltreatment (CM) and depression are serious global issues with high prevalence lifelong impacts on physical mental health. CM has been proposed as a modifiable risk factor for that, if prevented, may contribute to reduction in the incidence of depressive disorders. Despite this, there is paucity reviews examining strength association between these variables. The aim this systematic review meta‐analysis was evaluate empirical evidence determine supported preventable depression. Methods A search performed July 2024 all peer‐reviewed journal articles written English relationship adult electronic databases EBSCOhost , Proquest Embase . Studies were included they measured before 18 years age independent variable dependent variable. excluded outcome grouped comorbidity did not report primary quantitative data. total 77 studies 516,302 participants met inclusion criteria review. Results random‐effects used generate pooled odds ratio from 87 effect estimates demonstrated that individuals history any 2.5 times more likely experience ( OR = 2.49 [95% CI: 2.25–2.76]). This increase remained regardless how screened Conclusions These findings confirmed strong High heterogeneity meta‐analytic results also suggested further research required applies consistent adjustments comorbidities confounding factors examines temporal variables establish causality.

Language: Английский

Citations

1
Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study DOI Creative Commons
Luísa Sório Flor, Caroline Stein,

Gabriela Gil

et al.

Nature Human Behaviour, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Language: Английский

Citations

1