Journal of Biomedical Nanotechnology,
Journal Year:
2023,
Volume and Issue:
19(5), P. 689 - 705
Published: May 1, 2023
Targeted
ultrasound
molecular
probes
are
the
core
technology
of
imaging,
which
connect
specific
antibodies
or
ligands
target
tissue
to
surface
contrast
agents,
enabling
microbubbles
actively
bind
tissue,
thereby
observing
imaging
at
cellular
level,
reflecting
changes
in
diseased
level.
Ultrasound
has
rapidly
developed
and
applied
diagnosis
treatment
breast,
thyroid,
cardiovascular
other
diseases,
as
well
targeted
drug
delivery
physical
therapy
tumors.
This
article
focuses
on
theoretical
innovation
technological
progress
micro/nano
probes,
key
technologies
new
technologies,
application
bubbles
recent
years.
The
integration
multifunctional
multimodal
treatment,
is
development
trend
probes.
Artificial
intelligence
will
serve
a
basic
tool
provide
technical
support
for
intelligent
imaging.
Applied Sciences,
Journal Year:
2023,
Volume and Issue:
13(13), P. 7623 - 7623
Published: June 28, 2023
Background:
Screening
for
elbow
osteochondritis
dissecans
(OCD)
using
ultrasound
(US)
is
essential
early
detection
and
successful
conservative
treatment.
The
aim
of
the
study
to
determine
diagnostic
accuracy
YOLOv8,
a
deep-learning-based
artificial
intelligence
model,
US
images
OCD
or
normal
elbow-joint
images.
Methods:
A
total
2430
were
used.
Using
YOLOv8
image
classification
object
performed
recognize
lesions
standard
views
joints.
Results:
In
binary
lesions,
values
from
confusion
matrix
following:
Accuracy
=
0.998,
Recall
0.9975,
Precision
1.000,
F-measure
0.9987.
mean
average
precision
(mAP)
comparing
bounding
box
detected
by
trained
model
with
true-label
was
0.994
in
YOLOv8n
0.995
YOLOv8m
model.
Conclusions:
joints
lesions.
Both
tasks
able
be
achieved
high
may
useful
mass
screening
at
medical
check-ups
baseball
elbow.
Sports Health A Multidisciplinary Approach,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 1, 2025
Background:
Large
language
model
(LLM)-based
artificial
intelligence
(AI)
chatbots,
such
as
ChatGPT
and
Gemini,
have
become
widespread
sources
of
information.
Few
studies
evaluated
LLM
responses
to
questions
about
orthopaedic
conditions,
especially
osteochondritis
dissecans
(OCD).
Hypothesis:
Gemini
will
generate
accurate
that
align
with
American
Academy
Orthopaedic
Surgeons
(AAOS)
clinical
practice
guidelines.
Study
Design:
Cohort
study.
Level
Evidence:
2.
Methods:
prompts
were
created
based
on
AAOS
guidelines
OCD
diagnosis
treatment,
from
collected.
Seven
fellowship-trained
surgeons
a
5-point
Likert
scale,
6
categories:
relevance,
accuracy,
clarity,
completeness,
evidence-based,
consistency.
Results:
exhibited
strong
performance
across
all
criteria.
mean
scores
highest
for
clarity
(4.771
±
0.141
[mean
SD]).
scored
relevance
accuracy
(4.286
0.296,
4.286
0.273).
For
both
LLMs,
the
lowest
evidence-based
(ChatGPT,
3.857
0.352;
3.743
0.353).
other
categories,
higher
than
scores.
The
consistency
between
2
LLMs
was
rated
at
an
overall
3.486
0.371.
Inter-rater
reliability
ranged
0.4
0.67
(mean,
0.59)
(0.67)
in
category
(0.4)
category.
Conclusion:
emphasizes
potential
gathering
clinically
relevant
answers
regarding
treatment
suggests
may
be
better
this
purpose
model.
Further
evaluation
information
procedures
conditions
necessary
before
can
recommended
source
Clinical
Relevance:
Little
is
known
ability
AI
provide
OCD.
International Journal of Computer Assisted Radiology and Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 17, 2024
Abstract
Purpose
Osteochondritis
dissecans
(OCD)
of
the
humeral
capitellum
is
a
common
cause
elbow
disorders,
particularly
among
young
throwing
athletes.
Conservative
treatment
preferred
for
managing
OCD,
and
early
intervention
significantly
influences
possibility
complete
disease
resolution.
The
purpose
this
study
to
develop
deep
learning-based
classification
model
in
ultrasound
images
computer-aided
diagnosis.
Methods
This
paper
proposes
OCD
method
images.
proposed
first
detects
detection
using
YOLO
then
estimates
probability
detected
region
VGG16.
We
hypothesis
that
performance
will
be
improved
by
eliminating
unnecessary
regions.
To
validate
method,
it
was
applied
158
subjects
(OCD:
67,
Normal:
91)
five-fold-cross-validation.
Results
demonstrated
achieved
mean
average
precision
(mAP)
over
0.95,
while
estimation
an
accuracy
0.890,
0.888,
recall
0.927,
F1
score
0.894,
area
under
curve
(AUC)
0.962.
On
other
hand,
when
constructed
entire
image,
accuracy,
precision,
recall,
score,
AUC
were
0.806,
0.932,
0.843,
0.928,
respectively.
findings
suggest
high-performance
potential
ultrasonic
Conclusion
introduces
method.
experimental
results
emphasize
effectiveness
focusing
on
Future
work
should
involve
evaluating
employing
physicians
during
medical
check-ups
OCD.
Applied Sciences,
Journal Year:
2023,
Volume and Issue:
13(24), P. 13256 - 13256
Published: Dec. 14, 2023
Carpal
tunnel
syndrome
(CTS)
is
caused
by
subsynovial
connective
tissue
fibrosis,
resulting
in
median
nerve
(MN)
mobility.
The
standard
evaluation
method
the
measurement
of
MN
cross-sectional
area
using
static
images,
and
dynamic
images
are
not
widely
used.
In
recent
years,
remarkable
progress
has
been
made
field
deep
learning
(DL)
medical
image
processing.
aim
present
study
was
to
evaluate
dynamics
CTS
hands
YOLOv5
model,
which
one
object
detection
models
DL.
We
included
20
normal
(control
group)
(CTS
group).
obtained
ultrasonographic
short-axis
carpal
recorded
motion
during
finger
flexion–extension,
evaluated
displacement
velocity.
model
showed
a
score
0.953
for
precision
0.956
recall.
radial–ulnar
3.56
mm
control
group
2.04
group,
velocity
4.22
mm/s
3.14
group.
scores
were
significantly
reduced
This
demonstrates
potential
DL-based
analysis
as
powerful
diagnostic
tool
CTS.
Journal of Bone and Joint Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 14, 2024
Background:
Ultrasonography
is
used
to
diagnose
osteochondritis
dissecans
(OCD)
of
the
humerus;
however,
its
reliability
depends
on
technical
proficiency
examiner.
Recently,
computer-aided
diagnosis
(CAD)
using
deep
learning
has
been
applied
in
field
medical
science,
and
high
diagnostic
accuracy
reported.
We
aimed
develop
a
learning-based
CAD
system
for
OCD
detection
ultrasound
images
evaluate
system.
Methods:
The
process
comprises
2
steps:
humeral
capitellum
an
object-detection
algorithm
classification
image
network.
Four-directional
elbow
throwing
arm
196
baseball
players
(mean
age,
11.2
years),
including
104
with
normal
findings
92
OCD,
were
training
validation.
An
external
dataset
20
(10
10
OCD)
was
A
confusion
matrix
area
under
receiver
operating
characteristic
curve
(AUC)
Results:
Clinical
evaluation
resulted
AUCs
all
4
directions:
0.969
anterior
long
axis,
0.966
short
0.996
posterior
0.993
axis.
thus
exceeded
0.9
directions.
Conclusions:
propose
detect
lesions
images.
achieved
directions
elbow.
This
model
may
be
useful
screening
during
checkups
reduce
probability
missing
lesion.
Level
Evidence:
Diagnostic
II
.
See
Instructions
Authors
complete
description
levels
evidence.
Diagnostics,
Journal Year:
2024,
Volume and Issue:
14(18), P. 2008 - 2008
Published: Sept. 11, 2024
Ultrasound
imaging
is
a
vital
tool
in
musculoskeletal
medicine,
with
the
number
of
publications
on
ultrasound-guided
surgery
increasing
recent
years,
especially
minimally
invasive
procedures
sports,
foot
and
ankle,
hand
surgery.
However,
ultrasound
has
drawbacks,
such
as
operator
dependency
image
obscurity.
Artificial
intelligence
(AI)
deep
learning
(DL),
subset
AI,
can
address
these
issues.
AI/DL
enhance
screening
practices
for
hip
dysplasia
osteochondritis
dissecans
(OCD)
humeral
capitellum,
improve
diagnostic
accuracy
carpal
tunnel
syndrome
(CTS),
provide
physicians
better
prognostic
prediction
tools
patients
knee
osteoarthritis.
Building
advancements,
DL
methods,
including
segmentation,
detection,
localization
target
tissues
medical
instruments,
also
have
potential
to
allow
surgeons
perform
more
accurately
efficiently.
This
review
summarizes
advances
diseases
provides
comprehensive
overview
utilization
particularly
focusing
Journal of Orthopaedic Research®,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 23, 2024
Abstract
This
study
emphasizes
the
importance
of
early
detection
osteonecrosis
femoral
head
(ONFH)
in
young
patients
on
long‐term
glucocorticoid
therapy,
including
those
with
acute
lymphoblastic
leukemia,
lupus,
and
other
diagnoses.
While
X‐ray
magnetic
resonance
imaging
(MRI)
are
standard
methods
for
staging
ONFH,
MRI
can
be
costly
time‐consuming.
The
research
focuses
utilizing
artificial
intelligence
(AI)
to
enhance
evaluation
radiographic
images
ONFH
detection.
involved
analyzing
from
102
control
hips
104
ONFH‐affected
at
Association
Research
Circulation
Osseous
(ARCO)
Stage
II
IIIa.
We
employed
transfer
learning
YOLOv8
model
object
detection,
using
80%
data
training
20%
validation,
then
assessed
accuracy
through
mean
average
precision
(mAP)
a
precision‐recall
curve.
Additionally,
AI
generated
synthetic
(sMRI)
Generative
Adversarial
Network
(GAN)
evaluated
their
similarity
original
MRI.
Results
showed
that
mAP
was
0.923
YOLOv8n
0.951
YOLOv8x.
GAN‐generated
sMRI
exhibited
lower
image
quality
compared
originals
but
maintained
potential
lesion
assessment.
Intrarater
reliability
among
evaluators
high.
findings
indicate
techniques,
particularly
GAN
generation,
effectively
assist
screening,
despite
some
limitations
quality.
Journal of Biomedical Materials Research Part B Applied Biomaterials,
Journal Year:
2024,
Volume and Issue:
112(12)
Published: Dec. 1, 2024
ABSTRACT
Histomorphometry
is
an
important
technique
in
the
evaluation
of
non‐traumatic
osteonecrosis
femoral
head
(ONFH).
Quantification
empty
lacunae
and
pyknotic
cells
on
histological
images
most
reliable
measure
ONFH
pathology,
yet
it
time
manpower
consuming.
This
study
focused
application
artificial
intelligence
(AI)
technology
to
tissue
image
evaluation.
The
aim
this
establish
automated
cell
counting
platform
using
YOLOv8
as
object
detection
model
evaluate
validate
its
accuracy.
From
30
rabbits,
270
were
prepared;
based
evaluations
by
three
researchers,
ground
truth
labels
created
classify
each
into
two
classes
(osteocytes
lacunae)
or
(osteocytes,
cells,
lacunae).
Two
then
annotated
image.
Transfer
learning
data
(80%
for
training
20%
validation)
was
performed
YOLOv8n
YOLOv8x
with
different
parameters.
To
accuracy
model,
mean
average
precision
(mAP
(50))
precision‐recall
curve
identified.
In
addition,
reliability
relative
manual
evaluated
linear
regression
analysis
five
unused
previous
experiments.
mAP
(50)
0.868
0.883
YOLOv8x.
0.735
0.750
model.
quantification
obtained
highly
correlated
data.
development
AI‐applied
will
significantly
reduce
effort
analysis.