Overcoming COVID-19 vaccine hesitancy among ethnic minorities: A systematic review of UK studies

Vaccine, Journal Year: 2022, Volume and Issue: 40(25), P. 3413 - 3432

Published: April 28, 2022

Language: Английский

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Mitigating Vaccine Hesitancy and Building Trust to Prevent Future Measles Outbreaks in England

Vaccines, Journal Year: 2023, Volume and Issue: 11(2), P. 288 - 288

Published: Jan. 28, 2023

Measles, a highly infectious respiratory viral infection associated with severe morbidity and mortality, is preventable when coverage the effective measles, mumps rubella vaccine (MMR) ≥95%. Vaccine hesitancy responsible for measles outbreaks in countries where had previously been eliminated, including England, one of ten threats to global public health identified by World Health Organization (WHO). Official administrative 2012–2021 data on incidence MMR England were reviewed alongside scoping literature review factors uptake England. Whilst has reduced significantly since 2012, sporadic have occurred geographic disparities variations coverage. Over last decade, fallen across all regions no area currently reaching WHO target 95% both doses necessary herd immunity. Factors overlap 3C (convenience, complacency confidence) model hesitancy. The COVID-19 pandemic reinforced pre-existing Increasing reducing requires allocated funding area-based targeted domiciliary community-specific immunisation services interventions, catch-up campaigns web-based decision aid tools.

Language: Английский

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Perceived threat of COVID‐19, attitudes towards vaccination, and vaccine hesitancy: A prospective longitudinal study in the UK

British Journal of Health Psychology, Journal Year: 2022, Volume and Issue: 27(4), P. 1354 - 1381

Published: June 1, 2022

Using the Health Belief Model as a conceptual framework, we investigated association between attitudes towards COVID-19, COVID-19 vaccinations, and vaccine hesitancy change in these variables over 9-month period UK cohort.

Language: Английский

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Jinhua Qinggan granules for non-hospitalized COVID-19 patients: A double-blind, placebo-controlled, and randomized controlled trial

Frontiers in Medicine, Journal Year: 2022, Volume and Issue: 9

Published: Aug. 1, 2022

Background Key findings from the World Health Organization Expert Meeting on Evaluation of Traditional Chinese Medicine (TCM) in treating coronavirus disease 2019 (COVID-19) reported that TCMs are beneficial, particularly for mild-to-moderate cases. The efficacy Jinhua Qinggan granules (JHQG) COVID-19 patients with mild symptoms has yet to be clearly defined. Methods We conducted a phase 2/3, double-blind, randomized, placebo-controlled trial evaluate and safety treatment JHQG mild, non-hospitalized, laboratory-confirmed patients. Participants were randomly assigned receive 5 g/sacket or placebo orally thrice daily 10 days. primary outcomes improvement clinical proportion tested negative viral polymerase chain reaction (PCR) after treatment. Secondary time recover changes white blood cells (WBC) acute reactants (C-reactive protein (CRP) ferritin) 10th day initiation. Results A total 300 (150 patients) patients). Baseline characteristics similar two groups. In modified intention-to-treat analysis, showed greater (82.67%) compared group (10.74%; rate difference: 71.93%; 95% CI 64.09–79.76). PCR was comparable (rate −4.67%; −15.76 6.42). contrast, all WBC, ferritin, CRP levels statistically significant decline ( P ≤ 0.044) treatment, but not latter = 0.077). median recovery COVID-19-related including cough, sputum, sore throat, dyspnea, headache, nasal obstruction, fatigue, myalgia shorter < 0.001 all). Three experienced adverse events (AEs) duringthe period group. Findings between per-protocol analysis included only who 100% adherence regimen. Conclusion Based AEs, it is concluded safe effective TCM symptomatic relief COVID-19. observed use would have important public health implications such Clinical Trial Registration prospectively registered www.clinicaltrials.gov registration number: NCT04723524.

Language: Английский

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Digital health literacy for COVID-19 vaccination and intention to be immunized: A cross sectional multi-country study among the general adult population

Frontiers in Public Health, Journal Year: 2022, Volume and Issue: 10

Published: Sept. 16, 2022

It is clear that medical science has advanced much in the past few decades with development of vaccines and this even true for novel coronavirus outbreak. By late 2020, COVID-19 were starting to be approved by national global regulators, across 2021, there was a rollout several vaccines. Despite rolling out vaccination programs successfully, been cause concern regarding uptake vaccine due hesitancy. In tackling hesitancy improving overall rates, digital health literacy (DHL) could play major role. Therefore, aim study assess its relevance vaccination.

Language: Английский

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COVID-19 vaccine hesitancy: a systematic review of barriers to the uptake of COVID-19 vaccine among adults in Nigeria

Bulletin of the National Research Centre/Bulletin of the National Research Center, Journal Year: 2023, Volume and Issue: 47(1)

Published: March 21, 2023

Abstract Background Since the outbreak of coronavirus (COVID-19) disease was reported in 2019, huge human and material resources have been expended globally to combat spread disease. Achieving herd immunity through mass vaccination remains an important strategy adopt war against this since it is practically impossible for 60–70% population achieve natural infection alone. Unfortunately, there widespread reports COVID-19 vaccine hesitancy. This study aims systematically review literature provide up-to-date assessment acceptance rates also explore factors impacting hesitancy among adults Nigeria. Main body abstract A systematic search indexed electronic peer-reviewed published from 2019 onwards conducted Science Direct, PubMed, ProQuest, EBSCOhost databases according PRISMA checklist Synthesis without meta-analysis (SWiM) reporting guidelines. Fifteen out 148 studies retrieved, met inclusion criteria these were critically appraised using Centre Evidence-Based Medicine Critical Appraisal Mixed Methods Tool, version 2018. Basic descriptive statistic (percentage) employed analysis various subgroups Nigeria, while a thematic facilitators barriers uptake Nigeria conducted. Acceptance ranging 24.3% 49.5% observed across four high-risk populations low-risk ranged 26.0% 86.2%. Themes such as socio-demographic factors, perception risk concerns about vaccine's safety efficacy act interchangeably vaccines, whereas political conspiracy theories, cost primarily uptake. Short conclusion Substantial heterogeneity More than half reviewed below 60.0%. multidisciplinary approach recommended engaging stakeholders, effectively address

Language: Английский

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COVID-19 vaccination coverage in Egypt: a large-scale national survey – to help achieving vaccination target, March-May, 2022

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Feb. 27, 2023

Abstract Background Only 57 countries have vaccinated 70% of their population against COVID-19, most them in high-income countries, whereas almost one billion people low-income remained unvaccinated. In March–May 2022, Egypt's Ministry Health and Population (MoHP) conducted a nationwide community-based survey to determine COVID-19 vaccine coverage people's perceptions vaccination order improve uptake confidence among Egyptians, as well prioritize interventions. Methods A cross-sectional population-based household Egyptians ≥ 18 years age was implemented two phases using multistage random sampling technique all Egypt’s 27 governorates. sample 18,000 subjects divided into 450 clusters 20 households each calculated proportion governorate the main occupation population. Participants were interviewed semistructured questionnaire that included demographics, information from card, history infection, reasons for refusal unvaccinated, experience subjects. Vaccination rates by dividing numbers total number participants. Bivariate multivariate analyses performed comparing unvaccinated identify risk factors low uptake. Results Overall 18,107 interviewed, mean 42 ± 16 58.8% females. Of them, 8,742 (48.3%) had 8,020 (44.3%) fully vaccinated. Factors associated with analysis included: groups (18–29 30–39) (ORs 2.0 (95% C.I. 1.8–2.2) 1.3 C.I.1.2–1.4), respectively), residences urban or frontier governorates 1.6 1.5–1.8) 1.2 1.1–1.4), housewives self-employed 1.2–1.4) married 1.2–1.4), primary secondary educated 1.1 1.01–1.2) 1.1(1.04–1.2) respectively). Vaccine hesitancy due fear adverse events (17.5%), mistrust (10.2%), concern over safety during pregnancy lactation (6.9%), chronic diseases (5.0%). Conclusions Survey identified lower Egypt compared WHO target. Communication programs targeting are needed eliminate barriers related convenience, side effects, effectively promote Findings could contribute significantly promotion guiding decision-making efforts on risky preventing hesitancy.

Language: Английский

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COVID-19 vaccine hesitancy among health workers in rural Uganda: A mixed methods study

Vaccine X, Journal Year: 2023, Volume and Issue: 13, P. 100260 - 100260

Published: Jan. 7, 2023

COVID-19 vaccination is the latest preventive intervention strategy in an attempt to control global pandemic. Its efficacy has come under scrutiny because of break through infections among vaccinated and need for booster doses. Besides, although health workers were prioritized vaccine most countries, anecdotal evidence points high levels reluctance take workers. We assessed hesitancy Dokolo district, northern Uganda.This was a mixed-method, cross-sectional descriptive study. A customised self-administered data collection tool used collect quantitative on characteristics, status factors or rejection uptake. conducted multivariable logistic regression assess association between selected exposures using Stata version 15. Conversely, qualitative collected key informant interviews (KIIs) 15 participants that purposively selected. Data analysed thematic content analysis with help NVivo 12.0.Of 346 enrolled, (13.3% [46/346]) hesitant. Factors associated included fear side effects (Adjusted Odds Ratio [AOR]: 2.55; 95% Confidence Interval [95%CI]: 1.00, 6.49) workers' lack trust information provided by authorities (AOR: 6.74; CI: 2.43, 18.72). Similar when we score. Fear effects, distrust stakeholders, barriers workers.A small proportion found be hesitant this The paucity safety information, which eroded they received vaccine, responsible up Uganda.

Language: Английский

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Better Late Than Never: Predictors of Delayed COVID-19 Vaccine Uptake in Poland

Vaccines, Journal Year: 2022, Volume and Issue: 10(4), P. 528 - 528

Published: March 29, 2022

In this study, regression models were created to explain the increase of COVID-19 vaccination rates in 378 Polish sub-regions. order trace factors that could willingness delay vaccination, compared for age groups 20 years and more 30 June 2020 31 January 2021. Initially high rates, rather than leading gradual exhaustion pool those wishing get vaccinated, a very good predictor share remainder willing do so, which increased divergence between sub-regions nominal rates. Support Eurosceptic anti-establishment parties was strong persistent vaccine hesitancy. Ideological from mainstream appeared reinforce hesitancy, relationship remained highly relevant even when controlling possible time or spatial lag. Markers social inclusion capital-voter turnout employment rate-remained statistically significant lag, thus implying clear relevance trust public message. The population with higher education factor as well, though 20-39 bracket it predicted rate, while all older brackets negative predictor-this implies people had already made up their minds. Delaying seems predominantly explainable by political views, well exclusion historical specificity On regional level, there actually paradoxical Spearmans Rho correlation (0.641) refusing mandatory kids percentage receiving vaccine, further undermines idea overall observed hesitancy any meaningful way affected anti-vaccine movements.

Language: Английский

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Relationship between mental health and substance abuse on COVID-19 vaccine hesitancy in youth: A mixed methods longitudinal cohort study

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0313157 - e0313157

Published: Jan. 8, 2025

Background Mental health and substance use challenges are highly correlated in youth have been speculated to be associated with COVID-19 vaccine hesitancy. Literature has also suggested that mental increased during the pandemic. However, longitudinal relationship between hesitancy is not well established. Objective We examined health, Methods Youth ages 14 29-years participated a survey study. Participants provided sociodemographic, data, as qualitative quantitative information on their perspectives every two months February 2021 August 2021, 2022. Generalized estimating equation logistic regression models were used analyze effect of over time. Qualitative content area analyses identify trends attitudes. Results frequency hesitancy, significantly odds Additionally, decreases (OR: 0.80 (95% CI 0.66, 0.97)) when vaccines first began emerge, but increases 1.72 1.32, 2.26)) one year later. reported perceptions regarding safety efficacy primary determinants influencing hesitant, uncertain, acceptant changes attitudes time for some participants, health. Conclusions Increases Health policy agencies should aware potential impact youth, developing programs.

Language: Английский

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