Current Microbiology, Journal Year: 2025, Volume and Issue: 82(2)
Published: Jan. 3, 2025
Language: Английский
EFSA Journal, Journal Year: 2024, Volume and Issue: 22(1)
Published: Jan. 1, 2024
Abstract Listeria monocytogenes (in the meat, fish and seafood, dairy fruit vegetable sectors), Salmonella enterica feed, egg low moisture food sectors) Cronobacter sakazakii sector) were identified as bacterial safety hazards most relevant to public health that are associated with persistence in feed processing environment (FFPE). There is a wide range of subtypes these involved FFPE. While some specific more commonly reported persistent, it currently not possible identify universal markers (i.e. genetic determinants) for this trait. Common risk factors FFPE inadequate zoning hygiene barriers; lack hygienic design equipment machines; cleaning disinfection. A well-designed environmental sampling testing programme effective strategy contamination sources detect potentially persistent hazards. The establishment barriers measures within management system, during implementation hazard analysis critical control points, key prevent and/or Once suspected plant, 'seek-and-destroy' approach frequently recommended, including intensified monitoring, introduction continuation monitoring. Successful actions triggered by L. described, well interventions direct bactericidal activity. These could be efficient if properly validated, correctly applied verified under industrial conditions. Perspectives provided performing assessment combinations sector assess relative can persistence, based on bottom-up top-down approaches. Knowledge gaps related priorities future research provided.
Language: Английский
Citations
36
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Journal Year: 2024, Volume and Issue: 15(1)
Published: March 13, 2024
Abstract Staphylococcus aureus ( S. ) is a common pathogenic bacterium in animal husbandry that can cause diseases such as mastitis, skin infections, arthritis, and other ailments. The formation of biofilms threatens exacerbates infection by allowing the bacteria to adhere pathological areas livestock product surfaces, thus triggering health crises safety issues with products. To solve this problem, review, we provide brief overview harm caused its on byproducts (meat dairy products). We also describe ways which spreads animals threats it poses industry. processes molecular mechanisms involved biofilm are then explained. Finally, discuss strategies for removal eradication husbandry, including use antimicrobial peptides, plant extracts, nanoparticles, phages, antibodies. These reduce spread help maintain improve productivity ensure ecologically sustainable development
Language: Английский
Citations
14
Antibiotics, Journal Year: 2024, Volume and Issue: 13(7), P. 634 - 634
Published: July 9, 2024
The emergence of antimicrobial resistance (AMR) is a significant threat to global food security, human health, and the future livestock production. Higher rates use in dairy farming sheer lack new antimicrobials available for focused attention on question how production sector contributed development AMR paved path toward taking action curtail it targeted type farms. This paper aims provide an introduction phenomenon that has gained considerable recent past due its ever-increasing impact, drugs, farms, seeks discuss possibilities approaches such as digital health monitoring precision farming. Using sensors, data, knowledge, automation, etc., monitoring, well Precision Livestock Farming (PLF), expected enhance control minimize disease usage. work presents literature review current status trends understanding concept PLF, presentation usefulness PLF preventing AMR. study also analyses strengths weaknesses adopting incorporating technologies artificial intelligence areas further level use.
Language: Английский
Citations
12
Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11
Published: May 28, 2024
Bovine mastitis is one of the most common diseases dairy cattle. Even though different infectious microorganisms and mechanical injury can cause mastitis, bacteria are in cows. Staphylococci, streptococci, coliforms frequently diagnosed etiological agents Staphylococci that broadly divided into Staphylococcus aureus non-aureus staphylococci (NAS). NAS mainly comprised coagulase-negative species (CNS) some coagulase-positive coagulase-variable staphylococci. Current staphylococcal control measures ineffective, dependence on antimicrobial drugs not sustainable because low cure rate with treatment development resistance. Non-antimicrobial effective tools critically needed. This review describes current status S. cows flags areas knowledge gaps.
Language: Английский
Citations
9
Research in Veterinary Science, Journal Year: 2025, Volume and Issue: 185, P. 105547 - 105547
Published: Jan. 21, 2025
Language: Английский
Citations
1
Veterinary Quarterly, Journal Year: 2025, Volume and Issue: 45(1), P. 1 - 14
Published: Feb. 8, 2025
Bovine mammosphere-derived epithelial cell (MDEC) cultures are heterogeneous and enriched for stem progenitor cells. We previously reported that the bovine MDEC secretome, comprised of all bioactive factors secreted by cells, displays regenerative properties, exerts antimicrobial effects, modulates neutrophil activity, positioning it as a promising non-antibiotic biologic therapy infectious diseases important to dairy industry, like mastitis. Mastitis is defined inflammation udder, typically caused bacterial infection. The effect secretome on macrophages, first line defense against infections in unknown could impact utility To address this, we isolated monocytes from peripheral blood maintained them an unpolarized (M0) population or polarized into M1 M2 phenotypes. Macrophages cultured with MDECs were assessed their ability phagocytose labeled particles accumulate reactive oxygen species (ROS). used single-cell RNA sequencing (scRNA-seq) fluorescence-activated sorting (FACS) isolate subpopulation exert enhanced effects macrophages. found do not express cluster differentiation (CD) 73, surface enzyme marker mesenchymal stromal most strongly increased macrophage phagocytosis ROS accumulation. These findings will help optimize generation suitable treatment option
Language: Английский
Citations
1
Journal of Virology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 14, 2025
ABSTRACT Bovine mastitis, primarily caused by Staphylococcus aureus , significantly affects the dairy industry reducing milk production and quality. The rise of antibiotic-resistant bacteria has prompted need for alternative treatments. three newly isolated bacteriophages, OPT-SA02, OPT-SC01, OPT-SX11, were from chicken fecal sewage samples in South Korea. These bacteriophages characterized via physiological genomic analyses, identifying their therapeutic potential against S. -induced mastitis. identified as members Herelleviridae family, exhibiting stability across broad pH (2–12) temperature (37–70°C) ranges, well strong antibacterial activity at low multiplicity infection (MOI) levels. Genomic analysis revealed that conservation lysis-related genes (holin endolysin) is responsible lytic capabilities. Additionally, protein structural predictions multi-domain structures endolysins, enhancing potential. findings suggest OPT-SX11 show significant promise treatments bovine IMPORTANCE pathogens such xylosus remains a major challenge farming, leading to economic losses reduced increasing prevalence strains further complicates treatment, emphasizing strategies. This study identifies with effective these provides comprehensive insights into mechanisms. characterization conserved cassettes genetic diversity within related offering deeper understanding evolutionary relationships applications. Furthermore, structure endolysin derived architectures preserved catalytic cores, underscoring efficacy bacterial cell walls. advance mechanisms bacteriophage-mediated lysis highlight sustainable tools managing mastitis improving quality farming.
Language: Английский
Citations
1
Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2023, Volume and Issue: 23(1)
Published: Dec. 13, 2023
Abstract Staphylococcal enterotoxins (SEs), the major virulence factors of Staphylococcus aureus , cause a wide range food poisoning and seriously threaten human health by infiltrating supply chain at different phases manufacture, processes, distribution, market. The significant prevalence calls for efficient, fast, sensitive methods early detection SEs. Here, we provide comprehensive review hazards SEs in contaminated food, characteristic worldwide regulations SEs, various with extensive comparison discussion benefits drawbacks, mainly including biological detection, genetic mass spectrometry biosensors. We highlight biosensors screening purpose which are classified according to recognition elements such as antibodies, aptamers, molecularly imprinted polymers, T‐cell receptors, transducers optical, electrochemical, piezoelectric analyzed challenges monitoring conclude trends development novel should pay attention improve samples pretreatment efficiency, employ innovative nanomaterials, develop portable instruments. This provides new information insightful commentary, important innovation further samples.
Language: Английский
Citations
21
Veterinary Sciences, Journal Year: 2023, Volume and Issue: 10(7), P. 449 - 449
Published: July 8, 2023
Mastitis causes huge economic losses to dairy farmers worldwide, which largely negatively affects the quality and quantity of milk. decreases overall milk production, degrades quality, increases because being discarded, production costs due higher treatment labour premature culling. This review article discusses mastitis with respect its clinical epidemiology, pathogens involved, losses, basic advanced diagnostic tools that have been used in recent times diagnose effectively. There is an increasing focus on application novel therapeutic approaches as alternative conventional antibiotic therapy decreasing effectiveness antibiotics, emergence antibiotic-resistant bacteria, issue residues food chain, safety issues, environmental impacts. also discussed nanoparticles’/chitosan’s roles strains ethno-veterinary practices for cattle.
Language: Английский
Citations
18
FEMS Microbiology Reviews, Journal Year: 2024, Volume and Issue: 48(4)
Published: June 20, 2024
The emergence of new infectious diseases poses a major threat to humans, animals, and broader ecosystems. Defining factors that govern the ability pathogens adapt host species is therefore crucial research imperative. Pathogenic bacteria are particular concern, given dwindling treatment options amid continued expansion antimicrobial resistance. In this review, we summarize recent advancements in understanding bacterial adaptation, with an emphasis on humans related mammals. We focus particularly molecular mechanisms underlying key steps adaptation including colonization, nutrient acquisition, immune evasion, as well suggest areas for future investigation. By developing greater pathogenic bacteria, may uncover strategies target these microbes prevention environment.
Language: Английский
Citations
7