Knowledge, attitudes, and perceptions of COVID-19 vaccine and refusal to receive COVID-19 vaccine among healthcare workers in northeastern Ethiopia

BMC Public Health, Journal Year: 2022, Volume and Issue: 22(1)

Published: Jan. 18, 2022

Abstract Background Major efforts are being made to control the spread and impacts of coronavirus pandemic using vaccines. Ethiopia began on March 13, 2021, vaccinate healthcare workers (HCWs) for COVID-19 with AstraZeneca vaccine. However, willingness be vaccinated depends a large extent factors beyond availability This study aimed determine rate intention refuse vaccination associated among HCWs in northeastern Ethiopia. northeastern, Method An institution-based cross-sectional was employed 404 Dessie City, May, 2021. Data were collected, checked, coded, entered into EpiData Version 4.6 exported Statistical Package Social Sciences (SPSS) 25.0 cleaning analysis. The dependent variable receive independent variables included socio-demographic factors, knowledge, attitudes perceptions. A Binary logistic regression model used association between vaccine refusal variables. From bivariate analysis, p -values < 0.25 retained multivariable adjusted odds ratio (AOR), <0.05 at 95% confidence interval (CI) declared as significantly Results proportion overall good perception, positive about 62.5%, 60.5%, 52.3%, respectively; 64.0% wanted while 36.0% said that they would do so. Multivariable analysis identified negative (AOR: 3.057; 95%CI [1.860 - 5.026]) poor perceptions 4.73; [2.911 7.684]) vaccines COVID-19. Nearly half (46.9%) stated could worsen any pre-existing medical conditions 39.5% them thought cause infections. Conclusion get against relatively high HCWs. Negative towards anticipated significant vaccinated. Our findings may provide information management authorities stakeholders promote improve attitudes, knowledge uptake

Language: Английский

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Phytobioactive compounds as therapeutic agents for human diseases: A review

Food Science & Nutrition, Journal Year: 2023, Volume and Issue: 11(6), P. 2500 - 2529

Published: April 17, 2023

Phytobioactive compounds are plant secondary metabolites and bioactive abundantly present in medicinal plants have remarkable therapeutic potential. Oxidative stress antibiotic resistance major causes of present-day ailments such as diabetes, atherosclerosis, cardiovascular disorders, cancer, inflammation. The data for this review were collected from Google Scholar, PubMed, Directory Open Access Journals (DOAJ), Science Direct by using keywords: "Medicinal plants, compounds, Polyphenols, Alkaloids, Carotenoids etc." Several studies reported the pharmacological potential phytobioactives. alkaloids, terpenes, polysaccharides isolated showed antioxidant, anticancer, cytotoxic, anti-inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, antidiabetic activities. This literature was planned to provide comprehensive insight into biopharmacological phytobioactive compounds. techniques used extraction isolation bioassays required their biological activities antimicrobial, cytotoxic activities, been discussed. Characterization structural elucidation HPLC, TLC, FTIR, GC-MS/MS, NMR also concludes that may be alternative synthetic agents treatment various diseases.

Language: Английский

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Use of medicinal plants for COVID-19 prevention and respiratory symptom treatment during the pandemic in Cusco, Peru: A cross-sectional survey

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(9), P. e0257165 - e0257165

Published: Sept. 22, 2021

The burden of the COVID-19 pandemic in Peru has led to people seeking alternative treatments as preventives and treatment options such medicinal plants. This study aimed assess factors associated with use plants preventive or respiratory symptom related during Cusco, Peru.

Language: Английский

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Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria

European Journal of Integrative Medicine, Journal Year: 2021, Volume and Issue: 49, P. 102094 - 102094

Published: Nov. 28, 2021

Language: Английский

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A Review on Curcumin-Loaded Electrospun Nanofibers and their Application in Modern Medicine

JOM, Journal Year: 2022, Volume and Issue: 74(9), P. 3392 - 3407

Published: Feb. 24, 2022

Herbal drugs are safe and show significantly fewer side effects than their synthetic counterparts. Curcumin (an active ingredient primarily found in turmeric) shows therapeutic properties, but its commercial use as a medication is unrealized, because of doubts about potency. The literature reveals that electrospun nanofibers simplicity, efficiency, cost, reproducibility compared to other fabricating techniques. Forcespinning new technique minimizes limitations provides additional advantages electrospinning. Polymer-based nanofibers-whose lie stability, solubility, drug storage-overcome problems related delivery, like instability hydrophobicity. Curcumin-loaded polymer potency healing diabetic wounds vitro vivo. release profiles, cell viability, proliferation assays substantiate efficacy bone tissue repair delivery against lung, breast, colorectal, squamous, glioma, endometrial cancer cells. This review mainly discusses how interact with curcumin medical efficacy.

Language: Английский

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Medicinal plant sources and traditional healthcare practices of forest-dependent communities in and around Chunati Wildlife Sanctuary in southeastern Bangladesh

Environmental Sustainability, Journal Year: 2022, Volume and Issue: 5(2), P. 207 - 241

Published: June 1, 2022

Language: Английский

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Global Dietary and Herbal Supplement Use during COVID-19—A Scoping Review

Nutrients, Journal Year: 2023, Volume and Issue: 15(3), P. 771 - 771

Published: Feb. 2, 2023

During the first year of COVID-19 pandemic, lack cure and intensity global spread raised a common awareness health. The aim this scoping review is to summarize dietary supplement use globally during two years pandemic. A systematic search was conducted in December 2021 following PRISMA guidelines. PubMed, ERIC, Scopus databases were searched, 956 results screened for eligibility. Fourteen cross-sectional studies from 11 countries 3 continents examined. All large population surveys investigating healthy eating COVID-19. Vitamin C, vitamin D, zinc multivitamins most widely reported, as well natural/herbal products such ginger honey. reason cited supplements strengthen immune system prevent infection These reported that populations are relying on healthcare providers, family, friends, social media learn about use. Future treatment should include more evidence

Language: Английский

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Phyto-derived metal nanoparticles: Prominent tool for biomedical applications

OpenNano, Journal Year: 2023, Volume and Issue: 14, P. 100192 - 100192

Published: Oct. 13, 2023

Nanoparticles (NPs), despite of very small in size have extraordinary power and functional ability, forms the backbone nanomaterials science, utilizes it diverse fields. Many conventional methods can be employed for fabrication NPs, but required either high energy with producing toxic byproducts that degrades an environment. Therefore, a green approach is needed to save Green provide simple, straightforward, cost-effective environmentally-safe NPs synthesis. Plant derived one best supreme sustainable routes preparation NPs. As plant metal gains more attention due their synthesis significant biomedical appliances. In present review, we concentrated on (Ag, Au, Cu, Ni, Zn Ti) morphologies applications. Also discussed therapeutic applications future perspective

Language: Английский

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Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(16), P. 8792 - 8792

Published: Aug. 13, 2024

Phytochemicals have a long and successful history in drug discovery. With recent advancements analytical techniques methodologies, discovering bioactive leads from natural compounds has become easier. Computational like molecular docking, QSAR modelling machine learning, network pharmacology are among the most promising new tools that allow researchers to make predictions concerning products’ potential targets, thereby guiding experimental validation efforts. Additionally, approaches LC-MS or LC-NMR speed up compound identification by streamlining processes. Integrating structural computational biology aids lead identification, thus providing invaluable information understand how phytochemicals interact with targets body. An emerging approach is learning involving deep neural networks interrelate phytochemical properties diverse physiological activities such as antimicrobial anticancer effects.

Language: Английский

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Prevalence of Complementary and Alternative Medicine Use and Its Associated Factors among Iranian Diabetic Patients: A Cross-Sectional Study

Current Therapeutic Research, Journal Year: 2024, Volume and Issue: 100, P. 100746 - 100746

Published: Jan. 1, 2024

This cross-sectional study aimed to assess the prevalence and factors associated with use of complementary alternative medicine (CAM) among diabetic patients in Fasa, a city southern Iran. Data were collected from who visited endocrinology clinics at Fasa University Medical Science. A structured questionnaire was administered gather information on CAM use, including types modalities used, reasons for use. The patients' demographic clinical characteristics, such as age, gender, duration diabetes, glycosylated hemoglobin (HbA1c) levels, quality life (QoL) also recorded. Descriptive statistics used determine while logistic regression analysis employed identify total 376 participated study, more than 89% reporting within past year. Herbal preparations most commonly type CAM, rate 99.4%. Factors included psychological health, attitude towards safety belief synergistic effects combining routine medications previous positive experiences CAM. high highlight importance considering it diabetes management need healthcare professionals' engagement open discussions about their practices. Understanding influencing can inform providers policymakers developing appropriate strategies integrating approaches into conventional care.

Language: Английский

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