A review of thoracolumbar vertebrae number variation in sheep breeding DOI
Mesut Yıldırır,

Malmakov Nurlan,

Mussayeva Aizhan Seilkanovna

et al.

Small Ruminant Research, Journal Year: 2024, Volume and Issue: unknown, P. 107405 - 107405

Published: Nov. 1, 2024

Language: Английский

Unravelling the pangenomic signatures of selection for climate adaptation in sheep DOI

K.A. Saravanan,

J. L. Tiwari,

Kashif Khan

et al.

Authorea (Authorea), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 26, 2024

Climate change poses significant challenges to global livestock systems, necessitating a deeper understanding of how sheep adapt diverse environmental conditions. This study aimed identify genomic regions associated with hot and cold climate adaptation in 3066 from 90 breeds worldwide using medium-density SNP data. The were categorized into cold-adapted groups based on their origins. Through PCAdapt, we identified 132 under selection across all breeds, distinct signatures observed (53 regions) (49 adapted groups. These encompassed genes crucial for thermoregulation (DNAJB5, SYCP2, TCF7, TSHR, NPR1, MSRB3), coat colour (MITF, DCTN2) immune response (CCL26, CDH1, TNFSF12). Functional enrichment analysis revealed biological processes pathways adaptation, including keratin filament organization cytokine receptor binding calcium ion breeds. Protein-protein interaction networks highlighted key hub like TP53 S100A16, implicating roles mechanisms. Overlapping signals datasets, several corroborated by previous studies. Our findings contribute the resilience provide genetic markers future breeding strategies at enhancing sustainability productivity changing climatic

Language: Английский

Citations

1
Genome‐wide scans for signatures of selection in North African sheep reveals differentially selected regions between fat‐ and thin‐tailed breeds DOI
Slim Ben Jemaa,

Ghazi Yahyaoui,

Samia Kdidi

et al.

Animal Genetics, Journal Year: 2024, Volume and Issue: 56(1)

Published: Nov. 21, 2024

Abstract North Africa counts several sheep breeds that can be categorized as fat‐ and thin‐tailed. The former are well adapted to dryland environments. In this study, we used 50K genome‐wide single nucleotide polymorphism profiles from 462 animals representing nine fat‐tailed 13 thin‐tailed across localize genomic regions putatively under differential selective pressures between the two types of breeds. We observed genetic clines east west north south. east–west cline separates breeds, with exception Algerian Barbarine, which is closely related a genetically homogeneous cluster Moroccan Using combination three extended haplotype homozygosity tests, detected seven candidate divergent selection sheep. strongest signals reside on chromosomes 1 13, latter spanning BMP2 gene, known associated fat‐tail phenotype. Overall, in overlap genes adaptation desert‐like environments including adipogenesis, heat drought tolerance. Our results confirm previously reported target but also reveal novel specifically African populations.

Language: Английский

Citations

1
Examination of homozygosity runs and selection signatures in native goat breeds of Henan, China DOI Creative Commons

Weifeng Peng,

Yiyuan Zhang, Lei Gao

et al.

BMC Genomics, Journal Year: 2024, Volume and Issue: 25(1)

Published: Dec. 6, 2024

Language: Английский

Citations

1
A review of thoracolumbar vertebrae number variation in sheep breeding DOI
Mesut Yıldırır,

Malmakov Nurlan,

Mussayeva Aizhan Seilkanovna

et al.

Small Ruminant Research, Journal Year: 2024, Volume and Issue: unknown, P. 107405 - 107405

Published: Nov. 1, 2024

Language: Английский

Citations

0